RESEARCHER IDENTIFIERS
ORCID ID: 0000-0001-9999-7223
Scopus Author ID: 9638433400
Researcher ID: A-3860-2012
EDUCATION/QUALIFICATIONS
Since Jan. 2020: National Scientific Qualification for Full Professor (Abilitazione Scientifica Nazionale per la Prima Fascia). S.C. 05/E2 Biologia Molecolare (sector: Molecular Biology)
Since Nov. 2019: Associate Professor. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.
Since 2017 Affiliated researcher. Istituto Italiano di Tecnologia IIT@Sapienza. Center for Life Nanoscience - CLNS
Since 2014: Member of the Adjunct Faculty (2014-2019) and Guest Investigator (since 2019). The Rockefeller University, New York, USA.
Dec. 2011-Oct. 2019: Assistant Professor. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.
Nov. 2010-Nov. 2011: Postdoctoral Fellow. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.
June 2009-Oct 2010: Director of the Rockefeller University Stem Cell Derivation Core. Center for the derivation of human embryonic stem cell (hESC) and human induced pluripotent stem cell (hiPS) lines with a normal as well as diseased genetic background.
April 2008-Nov. 2011: Long term Human Frontier Science Program (HFSP) fellowship.
May 2007-Oct 2010: Postdoctoral Associate. Laboratory of Stem Cell Biology and Molecular Embryology (Brivanlou Lab). The Rockefeller University, New York, USA.
Jan.-April 2007: Short term Institute Pasteur - Fondazione Cenci-Bolognetti fellowship. Department of Genetics and Molecular Biology, Sapienza University, Rome, Italy.
Feb. 28, 2007: PhD Degree in Genetics and Molecular Biology with the thesis: “Rescue of dystrophin synthesis and body-wide muscle function in mdx dystrophic mice by antisense-snRNA mediated exon-skipping”.
Nov. 2003-Feb. 2007: PhD Course in Genetics and Molecular Biology. Department of Genetics and Molecular Biology, Sapienza University, Rome, Italy.
July 17, 2003 Graduated with honours (110/110 cum laude) in Biological Sciences with the Thesis “RNA interference in cellule di mammifero: costruzione di nuovi vettori per l'espressione stabile di siRNA” (“RNA interference in mammalian cells: construction of new vectors for the stable expression of siRNAs”).
Nov. 1998-July 2003: Sciences Faculty, Sapienza University, Rome, Italy.Course in Biological Sciences (Molecular Biology section).
PROFESSIONAL AND RESEARCH EXPERIENCE
Awards
• Acknowledgement for the excellence in University teaching 2017-18 and 2020-21. Awarded by the Faculty of Sciences of the Sapienza University to the top 5% of the teachers.
• PNI (National Prize for Innovation, Italy) 2017: special award for Best Project for Equal Opportunities - startup project HoMoLoG.
• 1st Award at the business plan competition StartCup Lazio 2017 - startup project HoMoLoG.
• Winner of the Bioeconomy Rome 2012 Award “For the most innovative Italian intuitions of 2011 in the field of biomedical sciences”. Awarded by CNCCS (Collezione Nazionale di Composti Chimici e Centro Screening).
• Winner of the RNA Society 2008 poster award in the category “Genetics and Development”.
• Winner of a post-doctoral fellowship “Long term 2008 Human Frontier Science Program (HFSP)”.
• Winner of a post-doctoral fellowship “The New York Stem Cell Foundation (NYSCF)” (2008). The fellowship was declined by the candidate in favor of the “Long term 2008 Human Frontier Science Program (HFSP)”.
• Winner of the 2006 SIBBM (Italian Society of Biophysics and Molecular Biology) Award.
Full list of Publications available in ORCID: https://orcid.org/0000-0001-9999-7223
65 papers indexed in Scopus and/or WOS
Hirsch Index (H-Index): 24 (Scopus)
Patents
RM2007A000595
Title: Use of miRNA and siRNA in therapy
Inventors: Irene Bozzoni, Alessandro Fatica, Alessandro Rosa
Dep. 15-11-2007
RM2003A000335 (Foreign Ext. PCT/IT04/00038)
Title: Construction of a new vector for siRNA in vivo expression
Inventors: Irene Bozzoni, Michela Denti, Alessandro Rosa
Dep. 9-7-2003
Patent licensed to Promega Corporation for the commercialization of the product GeneClip™ U1 Hairpin Cloning Systems.
Grants as PI
2021-2022 Regione Lazio - POR FESR LAZIO 2014-2020 “PROGETTI DI GRUPPI DI RICERCA 2020”. Soluzione Integrata di Microscopia Brillouin Avanzata (SIMBA) (project number: A0375-2020-36389)
2019-2021 Istituto Pasteur Italia - Fondazione Cenci Bolognetti. Call for projects 2019. Study of the role of RNA-binding proteins in the neurodegenerative disease Amyotrophic Lateral Sclerosis
2019-2021 Sapienza University “Progetto di Ateneo” 2018. Identification and characterization of RNA binding proteins and non-coding RNAs with a role in human neural specification and neurodegenerative diseases.
2017-2018 AriSLA Pilot Grant 2016. StressFUS - Impairment of the stress response by mutant FUS in iPSC-derived human ALS motoneurons.
2015-2016 Sapienza University “Progetto di Ateneo” 2015. Study of pathways affected by mutations in the FUS gene in an iPSC-based ALS model system.
2014-2015 Sapienza University “Progetto di Ateneo” 2014. Identification of interactors of long non-coding RNAs involved in cell differentiation.
Organization of scientific meetings
2019-2021: International Winter School on Molecular Medicine. Sapienza University of Rome, Italy.
2012 and 2016: Coordinator of the “Stem Cells, iPS, Cancer Stem Cells” minisymposium. FISV(Italian Federation of Life Sciences) Meeting, Italy.
Editorial activity
Associate Editor of Stem Cell Research (specialty section of Frontiers in Cell and Developmental Biology, Frontiers in Genetics, Frontiers in Oncology and Frontiers in Bioengineering and Biotechnology).
Editor of Stem Cells International (Hindawi Publishing Corporation; E-ISSN:1687-9678).
Guest Editor for a special issue on “The RNA revolution in embryonic development and cell differentiation in health and disease”. Frontiers in Cell and Developmental Biology.
About 30 oral presentations in national or international conferences