ALESSANDRO ROSA

Associate professor

email: alessandro.rosa@uniroma1.it
phone: 0649912096
building: CU026
room: 32

RESEARCHER IDENTIFIERS

ORCID ID: 0000-0001-9999-7223
Scopus Author ID: 9638433400
Researcher ID: A-3860-2012

EDUCATION/QUALIFICATIONS

Since Jan. 2020: National Scientific Qualification for Full Professor (Abilitazione Scientifica Nazionale per la Prima Fascia). S.C. 05/E2 Biologia Molecolare (sector: Molecular Biology)

Since Nov. 2019: Associate Professor. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.

Since 2017 Affiliated researcher. Istituto Italiano di Tecnologia IIT@Sapienza. Center for Life Nanoscience - CLNS

Since 2014: Member of the Adjunct Faculty (2014-2019) and Guest Investigator (since 2019). The Rockefeller University, New York, USA.

Dec. 2011-Oct. 2019: Assistant Professor. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.

Nov. 2010-Nov. 2011: Postdoctoral Fellow. Department of Biology and Biotechnology “Charles Darwin”, Sapienza University, Rome, Italy.

June 2009-Oct 2010: Director of the Rockefeller University Stem Cell Derivation Core. Center for the derivation of human embryonic stem cell (hESC) and human induced pluripotent stem cell (hiPS) lines with a normal as well as diseased genetic background.

April 2008-Nov. 2011: Long term Human Frontier Science Program (HFSP) fellowship.

May 2007-Oct 2010: Postdoctoral Associate. Laboratory of Stem Cell Biology and Molecular Embryology (Brivanlou Lab). The Rockefeller University, New York, USA.

Jan.-April 2007: Short term Institute Pasteur - Fondazione Cenci-Bolognetti fellowship. Department of Genetics and Molecular Biology, Sapienza University, Rome, Italy.

Feb. 28, 2007: PhD Degree in Genetics and Molecular Biology with the thesis: “Rescue of dystrophin synthesis and body-wide muscle function in mdx dystrophic mice by antisense-snRNA mediated exon-skipping”.

Nov. 2003-Feb. 2007: PhD Course in Genetics and Molecular Biology. Department of Genetics and Molecular Biology, Sapienza University, Rome, Italy.

July 17, 2003 Graduated with honours (110/110 cum laude) in Biological Sciences with the Thesis “RNA interference in cellule di mammifero: costruzione di nuovi vettori per l'espressione stabile di siRNA” (“RNA interference in mammalian cells: construction of new vectors for the stable expression of siRNAs”).

Nov. 1998-July 2003: Sciences Faculty, Sapienza University, Rome, Italy.Course in Biological Sciences (Molecular Biology section).

PROFESSIONAL AND RESEARCH EXPERIENCE

Awards

• Acknowledgement for the excellence in University teaching 2017-18 and 2020-21. Awarded by the Faculty of Sciences of the Sapienza University to the top 5% of the teachers.
• PNI (National Prize for Innovation, Italy) 2017: special award for Best Project for Equal Opportunities - startup project HoMoLoG.
• 1st Award at the business plan competition StartCup Lazio 2017 - startup project HoMoLoG.
• Winner of the Bioeconomy Rome 2012 Award “For the most innovative Italian intuitions of 2011 in the field of biomedical sciences”. Awarded by CNCCS (Collezione Nazionale di Composti Chimici e Centro Screening).
• Winner of the RNA Society 2008 poster award in the category “Genetics and Development”.
• Winner of a post-doctoral fellowship “Long term 2008 Human Frontier Science Program (HFSP)”.
• Winner of a post-doctoral fellowship “The New York Stem Cell Foundation (NYSCF)” (2008). The fellowship was declined by the candidate in favor of the “Long term 2008 Human Frontier Science Program (HFSP)”.
• Winner of the 2006 SIBBM (Italian Society of Biophysics and Molecular Biology) Award.

Full list of Publications available in ORCID: https://orcid.org/0000-0001-9999-7223

65 papers indexed in Scopus and/or WOS

Hirsch Index (H-Index): 24 (Scopus)

Patents

RM2007A000595
Title: Use of miRNA and siRNA in therapy
Inventors: Irene Bozzoni, Alessandro Fatica, Alessandro Rosa
Dep. 15-11-2007

RM2003A000335 (Foreign Ext. PCT/IT04/00038)
Title: Construction of a new vector for siRNA in vivo expression
Inventors: Irene Bozzoni, Michela Denti, Alessandro Rosa
Dep. 9-7-2003
Patent licensed to Promega Corporation for the commercialization of the product GeneClip™ U1 Hairpin Cloning Systems.

Grants as PI
2021-2022 Regione Lazio - POR FESR LAZIO 2014-2020 “PROGETTI DI GRUPPI DI RICERCA 2020”. Soluzione Integrata di Microscopia Brillouin Avanzata (SIMBA) (project number: A0375-2020-36389)
2019-2021 Istituto Pasteur Italia - Fondazione Cenci Bolognetti. Call for projects 2019. Study of the role of RNA-binding proteins in the neurodegenerative disease Amyotrophic Lateral Sclerosis
2019-2021 Sapienza University “Progetto di Ateneo” 2018. Identification and characterization of RNA binding proteins and non-coding RNAs with a role in human neural specification and neurodegenerative diseases.
2017-2018 AriSLA Pilot Grant 2016. StressFUS - Impairment of the stress response by mutant FUS in iPSC-derived human ALS motoneurons.
2015-2016 Sapienza University “Progetto di Ateneo” 2015. Study of pathways affected by mutations in the FUS gene in an iPSC-based ALS model system.
2014-2015 Sapienza University “Progetto di Ateneo” 2014. Identification of interactors of long non-coding RNAs involved in cell differentiation.

Organization of scientific meetings
2019-2021: International Winter School on Molecular Medicine. Sapienza University of Rome, Italy.
2012 and 2016: Coordinator of the “Stem Cells, iPS, Cancer Stem Cells” minisymposium. FISV(Italian Federation of Life Sciences) Meeting, Italy.

Editorial activity
Associate Editor of Stem Cell Research (specialty section of Frontiers in Cell and Developmental Biology, Frontiers in Genetics, Frontiers in Oncology and Frontiers in Bioengineering and Biotechnology).
Editor of Stem Cells International (Hindawi Publishing Corporation; E-ISSN:1687-9678).
Guest Editor for a special issue on “The RNA revolution in embryonic development and cell differentiation in health and disease”. Frontiers in Cell and Developmental Biology.

About 30 oral presentations in national or international conferences

Research products

11573/1704847 - 2024 - Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties

Benedetti, Maria Cristina; D'andrea, Tiziano; Colantoni, Alessio; Silachev, Denis; De Turris, Valeria; Boussadia, Zaira; Babenko, Valentina A.; Volovikov, Egor A.; Belikova, Lilia; Bogomazova, Alexandra N.; Pepponi, Rita; Whye, Dosh; Buttermore, Elizabeth D.; Tartaglia, Gian Gaetano; Lagarkova, Maria A.; Katanaev, Vladimir L.; Musayev, Ilya; Martinelli, Simone; Fucile, Sergio; Rosa, Alessandro - 01a Articolo in rivista

paper: HELIYON (Cell Press United Kingdom: Elsevier Limited) pp. - - issn: 2405-8440 - wos: WOS:001196436400001 (6) - scopus: 2-s2.0-85186464713 (5)

11573/1700969 - 2024 - Selective Reduction of Ca2+ Entry Through the Human NMDA Receptor: a Quantitative Study by Simultaneous Ca2+ and Na+ Imaging

D’Andrea, Tiziano; Benedetti, Maria Cristina; Monaco, Lucia; Rosa, Alessandro; Fucile, Sergio - 01a Articolo in rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. - - issn: 0893-7648 - wos: WOS:001145754400001 (0) - scopus: 2-s2.0-85182700650 (0)

11573/1704906 - 2024 - AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway

Naso, Francesco Davide; Polverino, Federica; Cilluffo, Danilo; Latini, Linda; Stagni, Venturina; Asteriti, Italia Anna; Rosa, Alessandro; Soddu, Silvia; Guarguaglini, Giulia - 01a Articolo in rivista

paper: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0925-4439 - wos: WOS:001209670600001 (3) - scopus: 2-s2.0-85187015134 (3)

11573/1726546 - 2024 - HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models

Silvestri, Beatrice; Mochi, Michela; Mawrie, Darilang; De Turris, Valeria; Colantoni, Alessio; Borhy, Beatrice; Medici, Margherita; Nathaniel Anderson, Eric; Giovanna Garone, Maria; Patrick Zammerilla, Christopher; Simula, Marco; Ballarino, Monica; Bhan Pandey &Amp;, Udai; Rosa, Alessandro - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:001352440200014 (0) - scopus: 2-s2.0-85208756946 (0)

11573/1670054 - 2023 - AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation

Anna Asteriti, Italia; Polverino, Federica; Stagni, Venturina; Sterbini, Valentina; Ascanelli, Camilla; Davide Naso, Francesco; Mastrangelo, Anna; Rosa, Alessandro; Paiardini, Alessandro; Lindon, Catherine; Guarguaglini, Giulia - 01a Articolo in rivista

paper: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:000935019100001 (10) - scopus: 2-s2.0-85148256341 (8)

11573/1668400 - 2023 - Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons

Garone, Maria Giovanna; Salerno, Debora; Rosa, Alessandro - 01a Articolo in rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:000920816800001 (3) - scopus: 2-s2.0-85146766524 (3)

11573/1687352 - 2023 - Collective behavior and self-organization in neural rosette morphogenesis

Miotto, M.; Rosito, M.; Paoluzzi, M.; De Turris, V.; Folli, V.; Leonetti, M.; Ruocco, G.; Rosa, A.; Gosti, G. - 01g Articolo di rassegna (Review)

paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:001053831200001 (8) - scopus: 2-s2.0-85168703260 (8)

11573/1679606 - 2023 - CRISPR/Cas9 and piggyBac Transposon-Based Conversion of a Pathogenic Biallelic TBCD Variant in a Patient-Derived iPSC Line Allows Correction of PEBAT-Related Endophenotypes

Muto, Valentina; Benigni, Federica; Magliocca, Valentina; Borghi, Rossella; Flex, Elisabetta; Pallottini, Valentina; Rosa, Alessandro; Compagnucci, Claudia; Tartaglia, Marco - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000987804600001 (1) - scopus: 2-s2.0-85159267590 (1)

11573/1692082 - 2023 - The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons

Tollis, P.; Vitiello, E.; Migliaccio, F.; D'ambra, E.; Rocchegiani, A.; Garone, M. G.; Bozzoni, I.; Rosa, A.; Carissimo, A.; Laneve, P.; Caffarelli, E. - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:001101872900003 (3) - scopus: 2-s2.0-85176472807 (3)

11573/1652462 - 2022 - Inducible motor neuron differentiation of human induced pluripotent stem cells in vivo

Chen, M.; Wang, X.; Li, C.; Lan, T.; Wei, Y.; Tang, C.; Zhou, X.; Zhou, R.; Rosa, A.; Zheng, X.; Ang, S.; Zhang, K.; Zou, Q.; Lai, L. - 01a Articolo in rivista

paper: CELL PROLIFERATION (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. - - issn: 0960-7722 - wos: WOS:000837703700001 (7) - scopus: 2-s2.0-85135558919 (7)

11573/1724545 - 2022 - Harnessing microfluidic biofabrication and cell printing to develop an in vitro bone pain model

Cidonio, Gianluca; Salaris, Federico; Kanczler, Janos; Soloperto, Alessandro; Scognamiglio, Chiara; Barbetta, Andrea; Dawson, Jonathan; Oreffo, Richard; Rosa, Alessandro; Ruocco, Giancarlo - 04h Atto di convegno in rivista scientifica o di classe A

paper: TISSUE ENGINEERING, PART A (New Rochelle NY: Mary Ann Liebert Inc.) pp. - - issn: 1937-3341 - wos: WOS:000821187300416 (0) - scopus: (0)

conference: Tissue Engineering and Regenerative Medicine International Society 2021 (Maastricht; Olanda)

11573/1645416 - 2022 - Culture of Human iPSC-Derived Motoneurons in Compartmentalized Microfluidic Devices and Quantitative Assays for Studying Axonal Phenotypes

Garone, M. G.; D'antoni, C.; Rosa, A. - 02a Capitolo o Articolo

book: Stem Cell Assays: Methods and Protocols - (978-1-0716-1978-0; 978-1-0716-1979-7)

11573/1651174 - 2022 - Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis

Hawkins, S.; Namboori, S. C.; Tariq, A.; Blaker, C.; Flaxman, C.; Dey, N. S.; Henley, P.; Randall, A.; Rosa, A.; Stanton, L. W.; Bhinge, A. - 01a Articolo in rivista

paper: STEM CELL REPORTS (Amsterdam : Elsevier) pp. 1650-1665 - issn: 2213-6711 - wos: WOS:000827571800003 (9) - scopus: 2-s2.0-85133974937 (11)

11573/1660709 - 2022 - Modelling skeletal pain harnessing tissue engineering

Iafrate, Lucia; Benedetti, Maria Cristina; Donsante, Samantha; Rosa, Alessandro; Corsi, Alessandro; Oreffo, Richard O. C.; Riminucci, Mara; Ruocco, Giancarlo; Scognamiglio, Chiara; Cidonio, Gianluca - 01g Articolo di rassegna (Review)

paper: IN VITRO MODELS (Cham: Springer) pp. 289-307 - issn: 2731-3433 - wos: WOS:001319771900002 (9) - scopus: (0)

11573/1662787 - 2022 - Emerging roles for the RNA-Binding protein HuD (ELAVL4) in nervous system diseases

Silvestri, Beatrice; Mochi, Michela; Garone, Maria Giovanna; Rosa, Alessandro - 01g Articolo di rassegna (Review)

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000896194600001 (10) - scopus: 2-s2.0-85143789148 (11)

11573/1564033 - 2021 - FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation

Birsa, N.; Ule, A. M.; Garone, M. G.; Tsang, B.; Mattedi, F.; Andrew Chong, P.; Humphrey, J.; Jarvis, S.; Pisiren, M.; Wilkins, O. G.; Nosella, M. L.; Devoy, A.; Bodo, C.; De La Fuente, R. F.; Fisher, E. M. C.; Rosa, A.; Viero, G.; Forman-Kay, J. D.; Schiavo, G.; Fratta, P. - 01a Articolo in rivista

paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. 1-16 - issn: 2375-2548 - wos: WOS:000675849000015 (34) - scopus: 2-s2.0-85110283030 (34)

11573/1549009 - 2021 - Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

Brighi, Carlo; Salaris, Federico; Soloperto, Alessandro; Cordella, Federica; Ghirga, Silvia; De Turris, Valeria; Rosito, Maria; Porceddu, Pier Francesca; D'antoni, Chiara; Reggiani, Angelo; Rosa, Alessandro; Di Angelantonio, Silvia - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. 1-22 - issn: 2041-4889 - wos: WOS:000656273400004 (42) - scopus: 2-s2.0-85105917597 (41)

11573/1567941 - 2021 - ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity

Garone, M. G.; Birsa, N.; Rosito, M.; Salaris, F.; Mochi, M.; De Turris, V.; Nair, R. R.; Cunningham, T. J.; Fisher, E. M. C.; Morlando, M.; Fratta, P.; Rosa, A. - 01a Articolo in rivista

paper: COMMUNICATIONS BIOLOGY ([London]: Springer Nature) pp. 1025- - issn: 2399-3642 - wos: WOS:000692407000006 (23) - scopus: 2-s2.0-85114160672 (26)

11573/1631026 - 2021 - PiggyBac vectors in pluripotent stem cell research and applications

Garone, M. G.; Rosa, A. - 02a Capitolo o Articolo

book: Methods in iPSC Technology - (9780323857666)

11573/1601513 - 2021 - A computational approach to investigate tdp-43 rna-recognition motif 2 c-terminal fragments aggregation in amyotrophic lateral sclerosis

Grassmann, G.; Miotto, M.; Di Rienzo, L.; Salaris, F.; Silvestri, B.; Zacco, E.; Rosa, A.; Tartaglia, G. G.; Ruocco, G.; Milanetti, E. - 01a Articolo in rivista

paper: BIOMOLECULES (Basel: MDPI) pp. 1905- - issn: 2218-273X - wos: WOS:000736331100001 (9) - scopus: 2-s2.0-85121301369 (9)

11573/1593905 - 2021 - Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons

Namboori, Seema C; Thomas, Patricia; Ames, Ryan; Hawkins, Sophie; Garrett, Lawrence O; Willis, Craig R G; Rosa, Alessandro; Stanton, Lawrence W; Bhinge, Akshay - 01a Articolo in rivista

paper: STEM CELL REPORTS (Amsterdam : Elsevier) pp. 3020-3035 - issn: 2213-6711 - wos: WOS:000731607400003 (15) - scopus: 2-s2.0-85120974608 (16)

11573/1575596 - 2021 - Editorial: The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease

Rosa, A.; Ciaudo, C.; Sumazin, P.; Fazi, F. - 01m Editorial/Introduzione in rivista

paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 1-3 - issn: 2296-634X - wos: WOS:000704152300001 (1) - scopus: 2-s2.0-85115924721 (1)

11573/1549404 - 2021 - Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

Tiago, T.; Hummel, B.; Morelli, F. F.; Basile, V.; Vinet, J.; Galli, V.; Mediani, L.; Antoniani, F.; Pomella, S.; Cassandri, M.; Garone, M. G.; Silvestri, B.; Cimino, M.; Cenacchi, G.; Costa, R.; Mouly, V.; Poser, I.; Yeger-Lotem, E.; Rosa, A.; Alberti, S.; Rota, R.; Ben-Zvi, A.; Sawarkar, R.; Carra, S. - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. 1-19 - issn: 2041-4889 - wos: WOS:000656257000003 (15) - scopus: 2-s2.0-85105454628 (17)

11573/1391093 - 2020 - Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling

Caputo, Luca; Granados, Alice; Lenzi, Jessica; Rosa, Alessandro; Ait-Si-Ali, Slimane; Puri, Pier Lorenzo; Albini, Sonia - 01a Articolo in rivista

paper: SKELETAL MUSCLE (London : BioMed Central) pp. - - issn: 2044-5040 - wos: WOS:000531624500001 (24) - scopus: 2-s2.0-85084308600 (24)

11573/1462047 - 2020 - High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons

Cavallo, F.; Troglio, F.; Faga, G.; Fancelli, D.; Shyti, R.; Trattaro, S.; Zanella, M.; D'agostino, G.; Hughes, J. M.; Cera, M. R.; Pasi, M.; Gabriele, M.; Lazzarin, M.; Mihailovich, M.; Kooy, F.; Rosa, A.; Mercurio, C.; Varasi, M.; Testa, G. - 01a Articolo in rivista

paper: MOLECULAR AUTISM (USA: BioMed Central Ltd) pp. - - issn: 2040-2392 - wos: WOS:000590512800001 (19) - scopus: 2-s2.0-85096225474 (20)

11573/1387940 - 2020 - Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System

Di Marco, Annalise Di; Vignone, Domenico; Gonzalez Paz, Odalys Gonzalez; Fini, Ivan; Battista, Maria Rosaria; Cellucci, Antonella; Bracacel, Elena; Auciello, Giulio; Veneziano, Maria; Khetarpal, Vinod; Rose, Mark; Rosa, Alessandro; Gloaguen, Isabelle; Monteagudo, Edith; Herbst, Todd; Dominguez, Celia; Muñoz-Sanjuán, Ignacio - 01a Articolo in rivista

paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000535559500205 (26) - scopus: 2-s2.0-85083871349 (29)

11573/1430664 - 2020 - Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3′UTR binding

Garone, Maria Giovanna; Alfano, Vincenzo; Salvatori, Beatrice; Braccia, Clarissa; Peruzzi, Giovanna; Colantoni, Alessio; Bozzoni, Irene; Armirotti, Andrea; Rosa, Alessandro - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000550057200140 (15) - scopus: 2-s2.0-85087975715 (17)

11573/1405967 - 2020 - FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention

Humphrey, Jack; Birsa, Nicol; Milioto, Carmelo; Mclaughlin, Martha; Ule, Agnieszka M; Robaldo, David; Eberle, Andrea B; Kräuchi, Rahel; Bentham, Matthew; Brown, Anna-Leigh; Jarvis, Seth; Bodo, Cristian; Garone, Maria G; Devoy, Anny; Soraru, Gianni; Rosa, Alessandro; Bozzoni, Irene; Fisher, Elizabeth M C; Mühlemann, Oliver; Schiavo, Giampietro; Ruepp, Marc-David; Isaacs, Adrian M; Plagnol, Vincent; Fratta, Pietro - 01a Articolo in rivista

paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:000574288800041 (63) - scopus: 2-s2.0-85088208506 (68)

11573/1427982 - 2020 - Trans-generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy

Martone, J.; Lisi, M.; Castagnetti, F.; Rosa, A.; Di Carlo, V.; Blanco, E.; Setti, A.; Mariani, D.; Colantoni, A.; Santini, T.; Perone, L.; Di Croce, L.; Bozzoni, I. - 01a Articolo in rivista

paper: EMBO MOLECULAR MEDICINE (Chichester : Wiley-Blackwell, 2009-) pp. - - issn: 1757-4676 - wos: WOS:000543752000001 (8) - scopus: 2-s2.0-85087294308 (8)

11573/1367089 - 2020 - Excess TPX2 interferes with microtubule disassembly and nuclei reformation at mitotic exit

Naso, Francesco D; Sterbini, Valentina; Crecca, Elena; Asteriti, Italia A; Russo, Alessandra D; Giubettini, Maria; Cundari, Enrico; Lindon, Catherine; Rosa, Alessandro; Guarguaglini, Giulia - 01a Articolo in rivista

paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-21 - issn: 2073-4409 - wos: WOS:000521944900115 (20) - scopus: 2-s2.0-85087951198 (22)

11573/1467643 - 2020 - The Aurora-A/TPX2 axis directs spindle orientation in adherent human cells by regulating NuMA and microtubule stability

Polverino, Federica; Naso, Francesco D; Asteriti, Italia A; Palmerini, Valentina; Singh, Divya; Valente, Davide; Bird, Alexander W; Rosa, Alessandro; Mapelli, Marina; Guarguaglini, Giulia - 01a Articolo in rivista

paper: CURRENT BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. - - issn: 0960-9822 - wos: WOS:000634648100012 (26) - scopus: 2-s2.0-85097762248 (27)

11573/1429819 - 2020 - HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade

Rea, Jessica; Menci, Valentina; Tollis, Paolo; Santini, Tiziana; Armaos, Alexandros; Garone, Maria Giovanna; Iberite, Federica; Cipriano, Andrea; Tartaglia, Gian Gaetano; Rosa, Alessandro; Ballarino, Monica; Laneve, Pietro; Caffarelli, Elisa - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000553100400002 (33) - scopus: 2-s2.0-85087954274 (30)

11573/1481384 - 2020 - HOTAIRM1 regulates neuronal differentiation by controlling NEUROGENIN 2 and the downstream neurogenic cascade

Rea, Jessica; Menci, Valentina; Tollis, Paolo; Santini, Tiziana; Tartaglia, Gian Gaetano; Rosa, Alessandro; Ballarino, Monica; Laneve, Pietro; Caffarelli, Elisa - 04f Poster

conference: 25th Annual Meeting of the RNA Society (Online)

book: 25th Annual Meeting of the RNA Society - ()

11573/1441390 - 2020 - Identification of molecular signatures in neural differentiation and neurological diseases using digital color-coded molecular barcoding

Salerno, D.; Rosa, A. - 01g Articolo di rassegna (Review)

paper: STEM CELLS INTERNATIONAL (SAGE-Hindawi) pp. - - issn: 1687-9678 - wos: WOS:000574291300001 (2) - scopus: 2-s2.0-85091699176 (2)

11573/1297233 - 2019 - Mutant FUS and ELAVL4 (HuD) aberrant crosstalk in Amyotrophic Lateral Sclerosis

De Santis, R.; Alfano, V.; De Turris, V.; Colantoni, A.; Santini, L.; Garone, M. G.; Antonacci, G.; Peruzzi, G.; Sudria-Lopez, E.; Wyler, E.; Anink, J. J.; Aronica, E.; Landthaler, M.; Pasterkamp, R. J.; Bozzoni, I.; Rosa, A. - 01a Articolo in rivista

paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 3818-3831 - issn: 2211-1247 - wos: WOS:000472715000011 (43) - scopus: 2-s2.0-85067263880 (44)

11573/1276468 - 2019 - Conversion of Human Induced Pluripotent Stem Cells (iPSCs) into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors

Garone, Maria G; De Turris, Valeria; Soloperto, Alessandro; Brighi, Carlo; De Santis, Riccardo; Pagani, Francesca; Di Angelantonio, Silvia; Rosa, Alessandro - 01a Articolo in rivista

paper: JOURNAL OF VISUALIZED EXPERIMENTS ([Boston, Mass. : MYJoVE Corp., 2006]-) pp. - - issn: 1940-087X - wos: WOS:000469977600054 (17) - scopus: 2-s2.0-85066930236 (22)

11573/1356388 - 2019 - Influence of substrate stiffness on human induced pluripotent stem cells: Preliminary results

Iberite, F.; Salerno, M.; Canale, C.; Rosa, A.; Ricotti, L. - 04b Atto di convegno in volume

conference: 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 (Berlin; Germany)

book: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS - (978-1-5386-1311-5)

11573/1321703 - 2019 - Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes

Pugliese, Giusj Monia; Salaris, Federico; Palermo, Valentina; Marabitti, Veronica; Morina, Nicolò; Rosa, Alessandro; Franchitto, Annapaola; Pichierri, Pietro - 01a Articolo in rivista

paper: DISEASE MODELS & MECHANISMS (Cambridge : Company of Biologists, 2007-) pp. - - issn: 1754-8403 - wos: WOS:000494678100002 (11) - scopus: 2-s2.0-85073666516 (11)

11573/1344999 - 2019 - The long noncoding RNA HOTAIRM1 contributes to neuronal differentiation by regulating Neurogenin 2 expression

Rea, Jessica; Menci, Valentina; Santini, Tiziana; Rosa, Alessandro; Ballarino, Monica; Laneve, Pietro; Caffarelli, Elisa - 04f Poster

conference: IBPM Annual Meeting (National Research Council (CNR), Rome)

book: IBPM Annual Meeting - Abstracts - ()

11573/1345007 - 2019 - HOTAIRM1 regulates neuronal differentiation by controlling NEUROGENIN 2 and the downstream neurogenic cascade

Rea, Jessica; Menci, Valentina; Tollis, Paolo; Santini, Tiziana; Alexandros, Armaos; Garone, Maria Giovanna; Iberite, Federica; Cipriano, Andrea; Tartaglia, Gian Gaetano; Rosa, Alessandro; Ballarino, Monica; Laneve, Pietro; Caffarelli, Elisa - 04f Poster

conference: EMBO | EMBL Symposium: The Non-Coding Genome (EMBL Heidelberg, Germany)

book: EMBO | EMBL Symposium: The Non-Coding Genome - ABSTRACT BOOK - ()

11573/1318360 - 2019 - 3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells

Salaris, Federico; Colosi, Cristina; Brighi, Carlo; Soloperto, Alessandro; Turris, Valeria De; Benedetti, Maria Cristina; Ghirga, Silvia; Rosito, Maria; Di Angelantonio, Silvia; Rosa, Alessandro - 01a Articolo in rivista

paper: JOURNAL OF CLINICAL MEDICINE (MDPI Publishing, Basel, Switzerland) pp. - - issn: 2077-0383 - wos: WOS:000498398500093 (43) - scopus: 2-s2.0-85084064985 (48)

11573/1308383 - 2019 - Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities

Salaris, Federico; Rosa, Alessandro - 01g Articolo di rassegna (Review)

paper: BRAIN RESEARCH (Amsterdam; Lausanne; New York; Oxford; Shannon; Tokyo: Elsevier) pp. - - issn: 0006-8993 - wos: WOS:000490627600023 (58) - scopus: 2-s2.0-85071118504 (65)

11573/1163289 - 2018 - Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS

Antonacci, Giuseppe; De Turris, Valeria; Rosa, Alessandro; Ruocco, Giancarlo - 01a Articolo in rivista

paper: COMMUNICATIONS BIOLOGY ([London]: Springer Nature) pp. 1-8 - issn: 2399-3642 - wos: WOS:000461126500139 (50) - scopus: 2-s2.0-85062398445 (56)

11573/1109389 - 2018 - Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector

De Santis, Riccardo; Garone, Maria Giovanna; Pagani, Francesca; De Turris, Valeria; Di Angelantonio, Silvia; Rosa, Alessandro - 01a Articolo in rivista

paper: STEM CELL RESEARCH (Amsterdam : Elsevier) pp. 189-196 - issn: 1873-5061 - wos: WOS:000434978900033 (34) - scopus: 2-s2.0-85046443648 (35)

11573/1344947 - 2018 - Neurogenin 2 expression is regulated by the long noncoding RNA HOTAIRM1 during in vitro neuronal differentiation

Menci, Valentina; Santini, Tiziana; Rea, Jessica; Rosa, Alessandro; Laneve, Pietro; Caffarelli, Elisa - 04f Poster

conference: XV FISV CONGRESS (Sapienza University of Rome, Italy)

book: Program and Abstracts of the XV FISV CONGRESS - ()

11573/1063175 - 2017 - Loss of miR-107, miR-181c and miR-29a-3p promote activation of Notch2 signaling in pediatric high-grade gliomas (pHGGs)

Catanzaro, Giuseppina; Sabato, Claudia; Russo, Michele; Rosa, Alessandro; Abballe, Luana; Besharat, Zein Mersini; Po, Agnese; Miele, Evelina; Bellavia, Diana; Chiacchiarini, Martina; Gessi, Marco; Peruzzi, Giovanna; Napolitano, Maddalena; Antonelli, Manila; Mastronuzzi, Angela; Giangaspero, Felice; Locatelli, Franco; Screpanti, Isabella; Vacca, Alessandra; Ferretti, Elisabetta - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000418896700243 (21) - scopus: 2-s2.0-85038414048 (22)

11573/1010900 - 2017 - FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis

De Santis, Riccardo; Santini, Laura; Colantoni, Alessio; Peruzzi, Giovanna; De Turris, Valeria; Alfano, Vincenzo; Bozzoni, Irene; Rosa, Alessandro - 01a Articolo in rivista

paper: STEM CELL REPORTS (Amsterdam : Elsevier) pp. ...-... - issn: 2213-6711 - wos: WOS:000415139400012 (66) - scopus: 2-s2.0-85030631001 (69)

11573/950933 - 2017 - FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

Errichelli, Lorenzo; Dini Modigliani, Stefano; Laneve, Pietro; Colantoni, Alessio; Legnini, Ivano; Capauto, Davide; Rosa, Alessandro; De Santis, Riccardo; Scarfò, Rebecca; Peruzzi, Giovanna; Lu, Lei; Caffarelli, Elisa; Shneider, Neil A.; Morlando, Mariangela; Bozzoni, Irene - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 14741- - issn: 2041-1723 - wos: WOS:000397796000001 (401) - scopus: 2-s2.0-85016645252 (415)

11573/1010898 - 2017 - Importin-beta and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function

Gilistro, Eugenia; De Turris, Valeria; Damizia, Michela; Verrico, Annalisa; Moroni, Sara; De Santis, Riccardo; Rosa, Alessandro; Lavia, Patrizia - 01a Articolo in rivista

paper: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 2564-2578 - issn: 0021-9533 - wos: WOS:000406770700013 (13) - scopus: 2-s2.0-85026638088 (13)

11573/1011169 - 2017 - Role of microRNAs in zygotic genome activation: modulation of mRNA during embryogenesis

Rosa, Alessandro; Brivanlou, Ali H. - 02a Capitolo o Articolo

book: Methods in Molecular Biology - (978-1-4939-6986-9; 978-1-4939-6988-3)

11573/867977 - 2016 - Mapping the amide I absorption in single bacteria and mammalian cells with resonant infrared nanospectroscopy

Baldassarre, Leonetta; Giliberti, Valeria; Rosa, Alessandro; Ortolani, Michele; Bonamore, Alessandra; Baiocco, Paola; Kjoller, K.; Calvani, Paolo; Nucara, Alessandro - 01a Articolo in rivista

paper: NANOTECHNOLOGY (Bristol, United Kingdom: IOP Publishing Limited) pp. 075101- - issn: 0957-4484 - wos: WOS:000368935000006 (57) - scopus: 2-s2.0-84955465361 (56)

11573/892343 - 2016 - Protein clustering in chemically stressed HeLa cells studied by infrared nanospectroscopy

Giliberti, Valeria; Baldassarre, Leonetta; Rosa, Alessandro; De Turris, Valeria; Ortolani, Michele; Calvani, Paolo; Nucara, Alessandro - 01a Articolo in rivista

paper: NANOSCALE (Cambridge,UK: RCS PUBLISHING -Royal Society of Chemistry) pp. 17560-17567 - issn: 2040-3364 - wos: WOS:000386244400022 (18) - scopus: 2-s2.0-84991573866 (18)

11573/877188 - 2016 - Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases

Lenzi, Jessica; Pagani, Francesca; De Santis, Riccardo; Limatola, Cristina; Bozzoni, Irene; Di Angelantonio, Silvia; Rosa, Alessandro - 01a Articolo in rivista

paper: STEM CELL RESEARCH (Amsterdam : Elsevier) pp. 140-147 - issn: 1873-5061 - wos: WOS:000385278000026 (29) - scopus: 2-s2.0-84974720903 (31)

11573/845821 - 2016 - Long Noncoding RNA Regulation of Pluripotency

Rosa, Alessandro; Ballarino, Monica - 01a Articolo in rivista

paper: STEM CELLS INTERNATIONAL (SAGE-Hindawi) pp. 1-9 - issn: 1687-9678 - wos: WOS:000371082500001 (46) - scopus: 2-s2.0-84949949298 (54)

11573/892273 - 2016 - Divergent lncRNAs take the lead on pluripotent cell differentiation

Rosa, Alessandro; Ballarino, Monica - 01a Articolo in rivista

paper: STEM CELL INVESTIGATION (Hong Kong : AME Publishing Company) pp. 1-3 - issn: 2313-0792 - wos: (0) - scopus: 2-s2.0-84995407545 (2)

11573/832744 - 2015 - Pur-alpha functionally interacts with FUS carrying ALS-associated mutations

Di Salvio, Michela; Piccinni, Violetta; Gerbino, Valeria; Mantoni, Federico; Camerini, Serena; Lenzi, Jessica; Rosa, Alessandro; Chellini, Lidia; Loreni, Fabrizio; Carrì, Maria Teresa; Bozzoni, Irene; Cozzolino, Mauro; Cestra, Gianluca - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. 1-11 - issn: 2041-4889 - wos: WOS:000209870000013 (23) - scopus: 2-s2.0-84961132825 (23)

11573/780455 - 2015 - Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice

Garofalo, Stefano; D'alessandro, Giuseppina; Chece, Giuseppina; Brau, Frederic; Maggi, Laura; Rosa, Alessandro; Porzia, Alessandra; Mainiero, Fabrizio; Esposito, Vincenzo; Lauro, Clotilde; Benigni, Giorgia; Bernardini, Giovanni; Santoni, Angela; Limatola, Cristina - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 6623-6636 - issn: 2041-1723 - wos: WOS:000353041300004 (106) - scopus: 2-s2.0-84926359060 (108)

book: Nature Communications - ()

11573/805324 - 2015 - ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons

Lenzi, Jessica; De Santis, Riccardo; Turris, Valeria De; Morlando, Mariangela; Laneve, Pietro; Calvo, Andrea; Caliendo, Virginia; Chiò, Adriano; Rosa, Alessandro; Bozzoni, Irene - 01a Articolo in rivista

paper: DISEASE MODELS & MECHANISMS (Cambridge : Company of Biologists, 2007-) pp. 755-766 - issn: 1754-8403 - wos: WOS:000356495500012 (117) - scopus: 2-s2.0-84937876670 (121)

11573/602782 - 2015 - N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics

M., Orticello; M., Fiore; P., Totta; M., Desideri; M., Barisic; D., Passeri; Lenzi, Jessica; Rosa, Alessandro; A., Orlandi; H., Maiato; D., Del Bufalo; F., Degrassi - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3325-3335 - issn: 0950-9232 - wos: WOS:000356592300011 (9) - scopus: 2-s2.0-84931576420 (12)

11573/559577 - 2014 - miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells

Rosa, Alessandro; Marilena D., Papaioannou; Joanna E., Krzyspiak; Ali H., Brivanlou - 01a Articolo in rivista

paper: DEVELOPMENTAL BIOLOGY (Elsevier B.V. Orlando, FL : Academic Press Incorporated) pp. 81-88 - issn: 0012-1606 - wos: WOS:000336347000007 (42) - scopus: 2-s2.0-84899993384 (42)

11573/526026 - 2013 - Non Coding RNA in Muscle Differentiation and Disease

Morlando, Mariangela; Rosa, Alessandro; Elisa, Caffarelli; Fatica, Alessandro; Bozzoni, Irene - 01a Articolo in rivista

paper: MICRORNA (Bentham Science Publishers) pp. 91-101 - issn: 2211-5374 - wos: (0) - scopus: 2-s2.0-85045248746 (0)

11573/523318 - 2013 - Regulatory Non-Coding RNAs in Pluripotent Stem Cells

Rosa, Alessandro; Brivanlou, Ali - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 14346-14373 - issn: 1422-0067 - wos: WOS:000322171700084 (34) - scopus: 2-s2.0-84880087880 (39)

11573/506075 - 2012 - FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

Morlando, Mariangela; Dini Modigliani, Stefano; Torrelli, Giulia; Rosa, Alessandro; Di Carlo, Valerio; Caffarelli, Elisa; Bozzoni, Irene - 01a Articolo in rivista

paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 4502-4510 - issn: 0261-4189 - wos: WOS:000312446700004 (184) - scopus: 2-s2.0-84871002507 (197)

11573/436659 - 2011 - APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis.

Alin, Vonica; Rosa, Alessandro; Brigitte L., Arduini; Ali H., Brivanlou - 01a Articolo in rivista

paper: DEVELOPMENTAL BIOLOGY (Elsevier B.V. Orlando, FL : Academic Press Incorporated) pp. 13-23 - issn: 0012-1606 - wos: WOS:000286547600002 (42) - scopus: 2-s2.0-78651227102 (41)

11573/436660 - 2011 - A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation

Rosa, Alessandro; Ali H., Brivanlou - 01a Articolo in rivista

paper: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 237-248 - issn: 0261-4189 - wos: WOS:000287179100003 (157) - scopus: 2-s2.0-78751640369 (175)

11573/436661 - 2010 - Synthetic mRNAs: Powerful tools for reprogramming and differentiation of human cells

Rosa, Alessandro; Ali H., Brivanlou - 01a Articolo in rivista

paper: CELL STEM CELL (Cambridge: Cell Press (an imprint of Elsevier)) pp. 549-550 - issn: 1934-5909 - wos: WOS:000284390500003 (17) - scopus: 2-s2.0-78049497848 (18)

11573/436662 - 2009 - microRNAs in early vertebrate development

Rosa, Alessandro; Ali H., Brivanlou - 01a Articolo in rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3513-3520 - issn: 1538-4101 - wos: WOS:000272218600022 (50) - scopus: 2-s2.0-70449707283 (54)

11573/436663 - 2009 - The miR-430/427/302 Family Controls Mesendodermal Fate Specification via Species-Specific Target Selection

Rosa, Alessandro; Francesca M., Spagnoli; Ali H., Brivanlou - 01a Articolo in rivista

paper: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 517-527 - issn: 1534-5807 - wos: WOS:000265470400008 (183) - scopus: 2-s2.0-64549094131 (190)

11573/359942 - 2008 - Role of microRNAs in myeloid differentiation.

Fatica, Alessandro; Rosa, Alessandro; Ballarino, Monica; De Marchis, Maria Laura; Rasmussen, Kd; Bozzoni, Irene - 01a Articolo in rivista

paper: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 1201-1205 - issn: 0300-5127 - wos: WOS:000261749200021 (19) - scopus: 2-s2.0-59149089005 (18)

11573/41995 - 2007 - The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation.

Ballarino, Monica; Sorrentino, A; Sthandier, O; Marchioni, M; Masella, B; Guarini, Anna; Fatica, Alessandro; Peschle, C; Bozzoni, Irene; Rosa, Alessandro; De Angelis, Fernanda Gabriella - 01a Articolo in rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19849-19854 - issn: 0027-8424 - wos: WOS:000251752200038 (241) - scopus: 2-s2.0-38049146022 (261)

11573/358943 - 2007 - Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia

Fazi, Francesco; Zardo, Giuseppe; V., Gelmetti; L., Travaglini; A., Ciolfi; L., Di Croce; Rosa, Alessandro; Bozzoni, Irene; F., Grignani; F., Lo Coco; P. G., Pelicci; Nervi, Clara - 01a Articolo in rivista

paper: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 4432-4440 - issn: 0006-4971 - wos: WOS:000246609100053 (71) - scopus: 2-s2.0-34248356405 (82)

11573/234568 - 2007 - Emerging role for microRNAs in acute promyelocytic leukemia

Nervi, Clara; Fazi, Francesco; Rosa, Alessandro; Fatica, Alessandro; Bozzoni, Irene - 01a Articolo in rivista

paper: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 73-84 - issn: 0070-217X - wos: WOS:000244386500005 (20) - scopus: 2-s2.0-33847004435 (19)

book: Acute Promyelocytic Leukemia - (9783540345923)

11573/104037 - 2006 - Chimeric Adeno-Associated Virus/Antisense U1 Small Nuclear RNA Effectively Rescues Dystrophin Synthesis and Muscle Function by Local Treatment of mdx Mice.

Denti, Ma; Rosa, Alessandro; D'antona, G; Sthandier, Olga Elena; De Angelis, Fernanda Gabriella; Nicoletti, Carmine; Allocca, M; Pansarasa, O; Parente, V; Musaro', Antonio; Auricchio, A; Bottinelli, R; Bozzoni, Irene - 01a Articolo in rivista

paper: HUMAN GENE THERAPY (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 565-574 - issn: 1043-0342 - wos: WOS:000237966300009 (41) - scopus: 2-s2.0-33646930313 (43)

11573/364616 - 2006 - Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model

Denti, Michela Alessandra; Rosa, Alessandro; G., D'antona; Sthandier, Olga Elena; De Angelis, Fernanda Gabriella; Nicoletti, Carmine; M., Allocca; O., Pansarasa; V., Parente; Musaro', Antonio; A., Auricchio; R., Bottinelli; Bozzoni, Irene - 01a Articolo in rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 3758-3763 - issn: 0027-8424 - wos: WOS:000236225300047 (112) - scopus: 2-s2.0-33644857020 (118)

11573/359930 - 2006 - MicroRNAs and Hematopoietic Differentiation

Fatica, Alessandro; Rosa, Alessandro; Fazi, Francesco; Ballarino, Monica; Morlando, Mariangela; De, F. G.; Caffarelli, E; Nervi, Clara; Bozzoni, Irene - 01a Articolo in rivista

paper: COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (Cold Spring Harbor Laboratory:500 Sunnyside Boulevard:Woodbury, NY 11797:(800)843-4388, (516)422-4100, EMAIL: cshpress@cshl.org, INTERNET: http://www.cshl.org, Fax: (516)422-4097) pp. 205-210 - issn: 0091-7451 - wos: WOS:000245962800027 (14) - scopus: 2-s2.0-34250654985 (15)

11573/465550 - 2006 - AML1/ETO causes heterochromatic gene silencing of the retinoic acid signaling pathway in Acute Myeloid Leukemia

Fazi, Francesco; Zardo, Giuseppe; Gelmetti, V; Travaglini, L; Ciolfi, A; Di Croce, L; Rosa, Alessandro; Bozzoni, Irene; Grignani, F; Lo Coco, F; Pelicci, Pg; Nervi, Clara - 04c Atto di convegno in rivista

paper: HAEMATOLOGICA (Fondaz Ferrata Storti:Strada Nuova 134, 27100 Pavia Italy:011 39 0382 531182, EMAIL: office@haematologica.it, Fax: 011 39 0382 27721) pp. 40-40 - issn: 0390-6078 - wos: (0) - scopus: 2-s2.0-32544444885 (28)

conference: IX Congress of the Italian Society of Experimental Hematology (Naples, Italy)

11573/363106 - 2005 - A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis.

Fazi, Francesco; Rosa, Alessandro; Fatica, Alessandro; Gelmetti, V; De Marchis, Maria Laura; Nervi, Clara; Bozzoni, Irene - 01a Articolo in rivista

paper: CELL (Cambridge Mass.: Elsevier Cambridge, MA: Cell Press) pp. 819-831 - issn: 0092-8674 - wos: WOS:000233814100016 (828) - scopus: 2-s2.0-28344438648 (904)

11573/363082 - 2004 - A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

Denti, Michela Alessandra; Rosa, Alessandro; Sthandier, Olga Elena; De Angelis, Fernanda Gabriella; Bozzoni, Irene - 01a Articolo in rivista

paper: MOLECULAR THERAPY (New York: Elsevier Cell Press San Diego CA: Academic Press, 2000-) pp. 191-199 - issn: 1525-0016 - wos: WOS:000223106100024 (66) - scopus: 2-s2.0-3042854926 (70)