ALESSANDRO PAIARDINI

Professore associato


email: alessandro.paiardini@uniroma1.it
telefono: 06/7027114
edificio: Dip Scienze Biochimiche
stanza: T01

CONTATTI
Telefono studio: 0649917700
Indirizzo email: alessandro.paiardini@uniroma1.it

TITOLI DI STUDIO (laurea e post-laurea)
• 2001 – Laurea cum laude in Biologia
• 2005 – PhD Thesis “Molecular Evolution of fold-type-I, PLP-dependent enzymes”.
• 2006 – Post Doctoral Fellowship (2 anni)

CARRIERA PROFESSIONALE
• 2006 – Ricercatore (Permanent Position) SSD BIO/10 (05/E1)
• 2007 – IT Administration of Biological Sciences and Biochemistry websites
• 2015 – Abilitazione Scientifica Nazionale PA Bio10 (05/E1)
• 2015 – Abilitazione Scientifica Nazionale PA Bio11 (05/E2)
• 2017 – Professore Associato (Permanent Position) SSD BIO/10 (05/E1)
• 2017 – Abilitazione Scientifica Nazionale PO Bio10 (05/E1)
• 2024 – Presidente Corso di Laurea in Bioinformatics

ATTIVITA’ DIDATTICA ATTUALE (anno 2018/19)
2015 To date Sapienza University of Rome Modulo BIOINFORMATICA (SSD BIO/10; CFU:6)
for the integrated course of BIOINFORMATICA E FARMACOLOGIA
(1041756) SSD BIO/10, BIO/14. CFU: 12 14456-Biotecnologie [L (DM 270/04)
- Ordin. 2010] - L-2 - Interfacoltà Farmacia e Medicina Scienze
Matematiche, Fisiche e Naturali Medicina e Psicologia - (Chair of the Integrated
Course (CFU:12) in 2015)
2016 To date Sapienza University of Rome STRUCTURE BIOSYNTHESIS AND ANALYSIS OF PROTEINS SSD BIO/10.
CFU: 6 28700- Genetica e Biologia Molecolare [L (DM 270/04)] - LM-6 -
Scienze Matematiche, Fisiche e Naturali - (Chair of the Course in English
CFU:6)
2017 - Sapienza University of Rome BIOCHEMISTRY I SSD BIO/10. CFU: 6 28613- Bioinformatics (L-2) Facoltà
di Farmacia e Medicina – Ingegneria dell’informazione, informatica e
statistica – Medicina e Odontoiatria - (Chair of the Course in English CFU:6)

RICONOSCIMENTI, PREMI E BORSE DI STUDIO
Year Title
2017 Awarded with the “Eccellenza per la didattica” by the Faculty of Sciences at Sapienza University, appointed to the top 5% teachers of the Faculty, Rome
2010 Awarded with the “medaglia di rappresentanza” by the President of the Italian Republic, as Outstanding Young Researcher at Sapienza University, during the Young International Forum (YIF), Rome
2001 Awarded by the Interdepartmental Research Centre for Models and Information Analysis in Biomedical Systems for the best 2000/2001 Thesis


DATI BIBLIOMETRICI

ORCID ID: https://orcid.org/0000-0001-9078-7545
(SCOPUS database)
Pubblicazioni totali: 125
Citazioni totali: 3000
H-index: 33

Produzione scientifica

11573/1707348 - 2024 - Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctions
Amormino, C.; Russo, E.; Tedeschi, V.; Fiorillo, M. T.; Paiardini, A.; Spallotta, F.; Rosano, L.; Tuosto, L.; Kunkl, M. - 01a Articolo in rivista
rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:001187533300001 (0) - scopus: 2-s2.0-85188131451 (0)

11573/1701072 - 2024 - Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase
Barile, Anna; Graziani, Claudio; Antonelli, Lorenzo; Parroni, Alessia; Fiorillo, Annarita; Di Salvo, Martino Luigi; Ilari, Andrea; Giorgi, Alessandra; Rosignoli, Serena; Paiardini, Alessandro; Contestabile, Roberto; Tramonti, Angela - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:001146773300001 (2) - scopus: 2-s2.0-85182849034 (2)

11573/1720191 - 2024 - An inherited TBX3 alteration in a prenatal case of ulnar‐mammary syndrome: Clinical assessment and functional characterization in Drosophila melanogaster
Bottillo, Irene; D'alessandro, Andrea; Ciccone, Maria Pia; Cestra, Gianluca; Di Giacomo, Gianluca; Silvestri, Evelina; Castori, Marco; Brancati, Francesco; Lenzi, Andrea; Paiardini, Alessandro; Majore, Silvia; Cenci, Giovanni; Grammatico, Paola - 01a Articolo in rivista
rivista: JOURNAL OF CELLULAR PHYSIOLOGY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-14 - issn: 0021-9541 - wos: WOS:001319932900001 (0) - scopus: 2-s2.0-85205253072 (0)

11573/1719569 - 2024 - The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target
Graziani, Claudio; Barile, Anna; Antonelli, Lorenzo; Fiorillo, Annarita; Ilari, Andrea; Vetica, Fabrizio; Di Salvo, Martino Luigi; Paiardini, Alessandro; Tramonti, Angela; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4984-5001 - issn: 1742-464X - wos: WOS:001314568800001 (0) - scopus: 2-s2.0-85204241869 (0)

11573/1711262 - 2024 - AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach
Rosignoli, Serena; Lustrino, Elisa; Conci, Alessio; Fabrizi, Alessandra; Rinaldo, Serena; Latella, Mariacarmela; Enzo, Elena; Prosseda, Gianni; De Rosa, Laura; De Luca, Michele; Paiardini, Alessandro - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. W29-W38 - issn: 0305-1048 - wos: WOS:001230689400001 (0) - scopus: 2-s2.0-85197797884 (1)

11573/1707220 - 2024 - Making Use of Averaging Methods in MODELLER for Protein Structure Prediction
Rosignoli, Serena; Lustrino, Elisa; Di Silverio, Iris; Paiardini, Alessandro - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-20 - issn: 1422-0067 - wos: WOS:001160493200001 (1) - scopus: 2-s2.0-85184717314 (1)

11573/1720302 - 2024 - An outlook on structural biology after AlphaFold: tools, limits and perspectives
Rosignoli, Serena; Pacelli, Maddalena; Manganiello, Francesca; Paiardini, Alessandro - 01g Articolo di rassegna (Review)
rivista: FEBS OPEN BIO (Hoboken NJ: Wiley & Sons Amsterdam : Elsevier) pp. 1-21 - issn: 2211-5463 - wos: WOS:001318796000001 (0) - scopus: 2-s2.0-85204642946 (0)

11573/1725671 - 2024 - Design and synthesis of novel compounds targeting both AURKA and HDAC enzymes.
Ruggieri, G.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Saccoliti, F; Arpacioglu, M.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R. - 04f Poster
congresso: EFMC-ISMC 2024 XXVIII EFMC International Symposium on Medicinal Chemistry (Rome, Italy)
libro: EFMC-ISMC 2024 XXVIII EFMC International Symposium on Medicinal Chemistry - ()

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 2682-2697 - issn: 1097-2765 - wos: WOS:001281962900001 (0) - scopus: 2-s2.0-85198588581 (0)

11573/1670827 - 2023 - Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1
Abdelbaki, Ahmed; Ascanelli, Camilla; Okoye, Cynthia N; Akman, H Begum; Janson, Giacomo; Min, Mingwei; Marcozzi, Chiara; Hagting, Anja; Grant, Rhys; De Luca, Maria; Asteriti, Italia Anna; Guarguaglini, Giulia; Paiardini, Alessandro; Lindon, Catherine - 01a Articolo in rivista
rivista: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:000892556700005 (2) - scopus: 2-s2.0-85143112003 (2)

11573/1670054 - 2023 - AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation
Anna Asteriti, Italia; Polverino, Federica; Stagni, Venturina; Sterbini, Valentina; Ascanelli, Camilla; Davide Naso, Francesco; Mastrangelo, Anna; Rosa, Alessandro; Paiardini, Alessandro; Lindon, Catherine; Guarguaglini, Giulia - 01a Articolo in rivista
rivista: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:000935019100001 (6) - scopus: 2-s2.0-85148256341 (6)

11573/1681779 - 2023 - When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases
Boi, Dalila; Rubini, Elisabetta; Breccia, Sara; Guarguaglini, Giulia; Paiardini, Alessandro - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000947160200001 (5) - scopus: 2-s2.0-85149819415 (5)

11573/1679516 - 2023 - Centaurea triumfetii essential oil chemical composition, comparative analysis, and antimicrobial activity of selected compounds
Carev, I; Gelemanović, A; Glumac, M; Tutek, K; Dželalija, M; Paiardini, A; Prosseda, G - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 7475- - issn: 2045-2322 - wos: WOS:001001538500012 (12) - scopus: 2-s2.0-85158121457 (13)

11573/1691212 - 2023 - A deep neural network for G-quadruplexes binding proteins classification
Di Luzio, F.; Paiardini, A.; Colonnese, F.; Rosato, A.; Panella, M. - 04b Atto di convegno in volume
congresso: 17th International Work-Conference on Artificial Neural Networks, IWANN 2023 (Ponta Delgada; Portugal)
libro: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) - (978-3-031-43084-8; 978-3-031-43085-5)

11573/1667930 - 2023 - A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression
Di Nisio, Elena; Licursi, Valerio; Mannironi, Cecilia; Buglioni, Valentina; Paiardini, Alessandro; Robusti, Giulia; Noberini, Roberta; Bonaldi, Tiziana; Negri, Rodolfo - 01a Articolo in rivista
rivista: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 0929-1903 - wos: WOS:000918402800001 (5) - scopus: 2-s2.0-85146853977 (5)

11573/1681512 - 2023 - First-in-class selective inhibitors of the lysine acetyltransferase KAT8
Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (5) - scopus: 2-s2.0-85159627845 (5)

11573/1681026 - 2023 - Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells
Kunkl, Martina; Amormino, Carola; Spallotta, Francesco; Caristi, Silvana; Fiorillo, Maria Teresa; Paiardini, Alessandro; Kaempfer, Raymond; Tuosto, Loretta - 01a Articolo in rivista
rivista: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000988435800001 (4) - scopus: 2-s2.0-85159695596 (3)

11573/1706561 - 2023 - Protein structure prediction in drug discovery
Paiardini, Alessandro - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. - - issn: 2218-273X - wos: WOS:001057594500001 (1) - scopus: 2-s2.0-85168740259 (1)

11573/1691811 - 2023 - PyPCN: protein contact networks in PyMOL
Rosignoli, Serena; Di Paola, Luisa; Paiardini, Alessandro - 01a Articolo in rivista
rivista: BIOINFORMATICS ([Oxford] : Oxford University Press) pp. 1-3 - issn: 1367-4811 - wos: WOS:001101066800001 (2) - scopus: 2-s2.0-85176804397 (1)

11573/1689849 - 2023 - Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
rivista: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (3) - scopus: 2-s2.0-85173505521 (3)

11573/1689850 - 2023 - Exploring innovative approaches to isolate a one-component c-di-GMP transducer: A pilot study
Scribani Rossi, C; Parisi, G; Paiardini, A; Rinaldo, S - 02a Capitolo o Articolo
libro: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY - ()

11573/1689461 - 2023 - The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine
Scribani-Rossi, Chiara; Antonia Molina-Henares, María; Angeli, Simone; Cutruzzola, Francesca; Paiardini, Alessandro; Espinosa-Urgel, Manuel; Rinaldo, Serena - 01a Articolo in rivista
rivista: FEMS MICROBIOLOGY LETTERS ([S.l.] : Blackwell S.l.] : Elsevier Science) pp. 1-9 - issn: 1574-6968 - wos: WOS:001046826600003 (1) - scopus: 2-s2.0-85168750549 (2)

11573/1687358 - 2023 - Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri
Trirocco, R.; Pasqua, M.; Tramonti, A.; Colonna, B.; Paiardini, A.; Prosseda, G. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:001049367300071 (2) - scopus: 2-s2.0-85168194551 (5)

11573/1679518 - 2023 - Fatty Acids Abolish Shigella Virulence by Inhibiting Its Master Regulator, VirF
Trirocco, Rita; Pasqua, Martina; Tramonti, Angela; Grossi, Milena; Colonna, Bianca; Paiardini, Alessandro; Prosseda, Gianni - 01a Articolo in rivista
rivista: MICROBIOLOGY SPECTRUM (Washington, DC : ASM Press, 2014-) pp. - - issn: 2165-0497 - wos: WOS:000981167800001 (2) - scopus: 2-s2.0-85163914189 (3)

11573/1652973 - 2022 - SARS-CoV-2 spike does not possess intrinsic superantigen-like inflammatory activity
Amormino, Carola; Tedeschi, Valentina; Paldino, Giorgia; Arcieri, Stefano; Fiorillo, Maria Teresa; Paiardini, Alessandro; Tuosto, Loretta; Kunkl, Martina - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000846047100001 (11) - scopus: 2-s2.0-85137600259 (12)

11573/1575071 - 2022 - A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins
Cutruzzolà, Francesca; Paiardini, Alessandro; Scribani Rossi, Chiara; Spizzichino, Sharon; Paone, Alessio; Giardina, Giorgio; Rinaldo, Serena - 01g Articolo di rassegna (Review)
rivista: COORDINATION CHEMISTRY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214228- - issn: 0010-8545 - wos: WOS:000706196900003 (3) - scopus: 2-s2.0-85115933139 (3)

11573/1652497 - 2022 - A Novel Hypothesis on Choroideremia-Manifesting Female Carriers: Could CHM In-Frame Variants Exert a Dominant Negative Effect? A Case Report
Di Giosaffatte, Niccolò; Valiante, Michele; Tricarico, Stefano; Parise, Giulia; De Negri, Anna Maria; Ricciotti, Guido; Florean, Lara; Paiardini, Alessandro; Bottillo, Irene; Grammatico, Paola - 01a Articolo in rivista
rivista: GENES (Basel : Molecular Diversity Preservation International) pp. 1-15 - issn: 2073-4425 - wos: WOS:000831455900001 (3) - scopus: 2-s2.0-85135136310 (4)

11573/1625113 - 2022 - Prediction and modeling of protein–protein interactions using “Spotted” peptides with a template-based approach
Gasbarri, C.; Rosignoli, S.; Janson, G.; Boi, D.; Paiardini, A. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 201- - issn: 2218-273X - wos: WOS:000763712100001 (1) - scopus: 2-s2.0-85123311952 (3)

11573/1672677 - 2022 - A short ERAP2 that binds IRAP is expressed in macrophages independently of gene variation
Mattorre, Benedetta; Caristi, Silvana; Donato, Simona; Volpe, Emilia; Faiella, Marika; Paiardini, Alessandro; Sorrentino, Rosa; Paladini, Fabiana - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000794712100001 (4) - scopus: 2-s2.0-85129003386 (7)

11573/1670824 - 2022 - A machine learning perspective on DNA and RNA G-quadruplexes
Paiardini, Alessandro; Rossi, Fabiana - 01a Articolo in rivista
rivista: CURRENT BIOINFORMATICS (Netherlands, BENTHAM SCIENCE PUBLISHERS) pp. - - issn: 1574-8936 - wos: WOS:000851376300001 (1) - scopus: 2-s2.0-85137335339 (1)

11573/1655650 - 2022 - DockingPie: a consensus docking plugin for PyMOL
Rosignoli, Serena; Paiardini, Alessandro - 01a Articolo in rivista
rivista: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. 4233-4234 - issn: 1367-4803 - wos: WOS:000824423300001 (15) - scopus: 2-s2.0-85141892299 (15)

11573/1661534 - 2022 - Boosting the full potential of PyMOL with structural biology plugins
Rosignoli, Serena; Paiardini, Alessandro - 01g Articolo di rassegna (Review)
rivista: BIOMOLECULES (Basel: MDPI) pp. 1764- - issn: 2218-273X - wos: WOS:000902276900001 (51) - scopus: 2-s2.0-85144708388 (57)

11573/1641216 - 2022 - Nutrient sensing and biofilm modulation: the example of L-arginine in Pseudomonas
Scribani Rossi, C; Barrientos-Moreno, L.; Paone, A.; Cutruzzola', F.; Paiardini, A.; Espinosa-Urgel, M.; Rinaldo, S. - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 4386- - issn: 1661-6596 - wos: WOS:000785501700001 (25) - scopus: 2-s2.0-85128190924 (27)

11573/1584599 - 2022 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 1625-1649 - issn: 1742-464X - wos: WOS:000717476400001 (3) - scopus: 2-s2.0-85118844105 (5)

11573/1615167 - 2021 - Pha-680626 is an effective inhibitor of the interaction between aurora-a and n-myc
Boi, D.; Souvalidou, F.; Capelli, D.; Polverino, F.; Marini, G.; Montanari, R.; Pochetti, G.; Tramonti, A.; Contestabile, R.; Trisciuoglio, D.; Carpinelli, P.; Ascanelli, C.; Lindon, C.; De Leo, A.; Saviano, M.; Di Santo, R.; Costi, R.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 13122- - issn: 1661-6596 - wos: WOS:000735123900001 (10) - scopus: 2-s2.0-85120777012 (10)

11573/1548792 - 2021 - Bacterial oxidases of the cytochrome bd family: redox enzymes of unique structure, function, and utility as drug targets
Borisov, V. B.; Siletsky, S. A.; Paiardini, A.; Hoogewijs, D.; Forte, E.; Giuffre, A.; Poole, R. K. - 01g Articolo di rassegna (Review)
rivista: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1280-1318 - issn: 1523-0864 - wos: WOS:000590857300001 (58) - scopus: 2-s2.0-85105655418 (56)

11573/1534289 - 2021 - The archaeal elongation factor EF-2 induces the release of aIF6 from 50S ribosomal subunit
Lo Gullo, Giada; De Santis, Maria Luisa; Paiardini, Alessandro; Rosignoli, Serena; Romagnoli, Alice; La Teana, Anna; Londei, Paola; Benelli, Dario - 01a Articolo in rivista
rivista: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 631297- - issn: 1664-302X - wos: WOS:000637212200001 (3) - scopus: 2-s2.0-85103823367 (3)

11573/1492549 - 2021 - Studying ggdef domain in the act: Minimize conformational frustration to prevent artefacts
Mantoni, F.; Scribani Rossi, C.; Paiardini, A.; Di Matteo, A.; Cappellacci, L.; Petrelli, R.; Ricciutelli, M.; Paone, A.; Cutruzzola', F.; Giardina, G.; Rinaldo, S. - 01a Articolo in rivista
rivista: LIFE (Basel: MDPI) pp. 1-13 - issn: 2075-1729 - wos: WOS:000610391100001 (4) - scopus: 2-s2.0-85100221529 (5)

11573/1573946 - 2021 - Phosphorylation, mg‐adp, and inhibitors differentially shape the conformational dynamics of the a‐loop of aurora‐a
Musavizadeh, Z.; Grottesi, A.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 567- - issn: 2218-273X - wos: WOS:000642785000001 (3) - scopus: 2-s2.0-85103937885 (3)

11573/1574100 - 2021 - Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer
Naso, F. D.; Boi, D.; Ascanelli, C.; Pamfil, G.; Lindon, C.; Paiardini, A.; Guarguaglini, G. - 01g Articolo di rassegna (Review)
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3917-3928 - issn: 0950-9232 - wos: WOS:000650165600001 (28) - scopus: 2-s2.0-85105789689 (27)

11573/1600685 - 2021 - Design and development of a versatile graphical user interface for assisting consensus docking analyses on therapeutic targets for cancer treatment.
Rosignoli, Serena; Paiardini, Alessandro - 04f Poster
congresso: EMBO Workshop - Systems approaches in cancer (Split; Croatia)
libro: Systems approaches in cancer - ()

11573/1558512 - 2021 - L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation
Scribani Rossi, Chiara; Mantoni, Federico; Giardina, Giorgio; Paiardini, Alessandro; Di Matteo, Adele; Cutruzzola', Francesca; Rinaldo, Serena - 04d Abstract in atti di convegno
congresso: efb 2021 (online)
libro: efb 2021 - ()

11573/1558505 - 2021 - Signal transduction and c-di-GMP second messenger: novel tools to investigare the mechanism of nutrient sensing.
Scribani Rossi, Chiara; Parisi, Giacomo; Giardina, Giorgio; Cutruzzola', Francesca; Paiardini, Alessandro; Rinaldo, Serena - 04d Abstract in atti di convegno
congresso: WEBPRO - Proteins on the Web 2021. (online)
libro: WEBPRO - Proteins on the Web 2021. - ()

11573/1553985 - 2021 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Tramonti, Angela; Paiardini, Alessandro; Contestabile, Roberto; Pochetti, Giorgio; Rinaldo, Serena; Paone, Alessio; Giardina, Giorgio; Cutruzzola', Francesca - 04d Abstract in atti di convegno
congresso: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research (online)
libro: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research Abstracts - ()

11573/1396096 - 2020 - Artemisinin derivatives with antimelanoma activity show inhibitory effect against human dna topoisomerase 1
Botta, Lorenzo; Filippi, Silvia; Zippilli, Claudio; Cesarini, Silvia; Bizzarri, Bruno Mattia; Cirigliano, Angela; Rinaldi, Teresa; Paiardini, Alessandro; Fiorucci, Diego; Saladino, Raffaele; Negri, Rodolfo; Benedetti, Pietro - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 1035-1040 - issn: 1948-5875 - wos: WOS:000535281200064 (19) - scopus: 2-s2.0-85087985664 (19)

11573/1656619 - 2020 - A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome
Bottillo, Irene; Valiante, Michele; Menale, Lucia; Paiardini, Alessandro; Papi, Laura; Janson, Giacomo; Sestini, Roberta; Iorio, Alessandra; De Simone, Paola; Frascione, Pasquale; Grammatico, Paola - 01a Articolo in rivista
rivista: DERMATOLOGY ONLINE JOURNAL (University of California:25 Lower Freeborn:Davis, CA 95616:(916)752-0365, (916)752-0208, Fax: (916)752-0355) pp. - - issn: 1087-2108 - wos: (0) - scopus: 2-s2.0-85091193097 (2)

11573/1463758 - 2020 - Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000595956300001 (10) - scopus: 2-s2.0-85096677891 (12)

11573/1473676 - 2020 - A single center retrospective review of patients from central italy tested for melanoma predisposition genes
De Simone, P; Bottillo, I; Valiante, M; Iorio, A; De Bernardo, C; Majore, S; D'angelantonio, D; Valentini, T; Sperduti, I; Piemonte, P; Eibenschutz, L; Ferrari, A; Carbone, A; Buccini, P; Paiardini, A; Silipo, V; Frascione, P; Grammatico, P - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-17 - issn: 1661-6596 - wos: WOS:000602971200001 (2) - scopus: 2-s2.0-85097557593 (2)

11573/1473622 - 2020 - Intronic determinants coordinate charme lncRNA nuclear activity through the interaction with MATR3 and PTBP1
Desideri, F.; Cipriano, A.; Petrezselyova, S.; Buonaiuto, G.; Santini, T.; Kasparek, P.; Prochazka, J.; Janson, G.; Paiardini, A.; Calicchio, A.; Colantoni, A.; Sedlacek, R.; Bozzoni, I.; Ballarino, M. - 01a Articolo in rivista
rivista: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:000601399100024 (22) - scopus: 2-s2.0-85098200912 (23)

11573/1486557 - 2020 - PyMod 3: a complete suite for structural bioinformatics in PyMOL
Janson, Giacomo; Paiardini, Alessandro - 01a Articolo in rivista
rivista: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. - - issn: 1367-4803 - wos: WOS:000693168900019 (75) - scopus: 2-s2.0-85108387165 (77)

11573/1416609 - 2020 - SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase
Martone, J.; Mariani, D.; Santini, T.; Setti, A.; Shamloo, S.; Colantoni, A.; Capparelli, F.; Paiardini, A.; Dimartino, D.; Morlando, M.; Bozzoni, I. - 01a Articolo in rivista
rivista: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. e49942- - issn: 1469-221X - wos: WOS:000528590900001 (21) - scopus: 2-s2.0-85084118101 (21)

11573/1458055 - 2020 - Insights into pparγphosphorylation and its inhibition mechanism
Montanari, R.; Capelli, D.; Yamamoto, K.; Awaishima, H.; Nishikata, K.; Barendregt, A.; Heck, A. J. R.; Loiodice, F.; Altieri, F.; Paiardini, A.; Grottesi, A.; Pirone, L.; Pedone, E.; Peiretti, F.; Brunel, J. M.; Itoh, T.; Pochetti, G. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4811-4823 - issn: 0022-2623 - wos: WOS:000535279800026 (22) - scopus: 2-s2.0-85084694697 (22)

11573/1648069 - 2020 - Structure and function of HD-GYP phosphodiesterases
Rinaldo, S.; Paiardini, A.; Paone, A.; Cutruzzola', F.; Giardina, G. - 02a Capitolo o Articolo
libro: Microbial Cyclic Di-Nucleotide Signaling - (978-3-030-33307-2; 978-3-030-33308-9)

11573/1389775 - 2020 - From PARP1 to TNKS2 inhibition: A structure-based approach
Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (11) - scopus: 2-s2.0-85087107488 (9)

11573/1343897 - 2019 - Custom scoring Aurora-A with SMINA
Esposito, Chiara; Grottesi, Alessandro; Janson, Giacomo; Paiardini, Alessandro - 04f Poster
congresso: New Frontiers in Structure-Based Drug Discovery (Firenze)
libro: New Frontiers in Structure-Based Drug Discovery - ()

11573/1244108 - 2019 - The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism
Guiducci, Giulia; Paone, Alessio; Tramonti, Angela; Giardina, Giorgio; Rinaldo, Serena; Bouzidi, Amani; Magnifico, Maria C; Marani, Marina; Menendez, Javier A; Fatica, Alessandro; Macone, Alberto; Armaos, Alexandros; Tartaglia, Gian G; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 1-16 - issn: 0305-1048 - wos: WOS:000473754300036 (29) - scopus: 2-s2.0-85067847112 (29)

11573/1263074 - 2019 - N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia
Ianniello, Zaira; Paiardini, Alessandro; Fatica, Alessandro - 01a Articolo in rivista
rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000463924400001 (58) - scopus: 2-s2.0-85067465851 (57)

11573/1625118 - 2019 - Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling
Janson, G.; Grottesi, A.; Pietrosanto, M.; Ausiello, G.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
rivista: PLOS COMPUTATIONAL BIOLOGY (San Francisco, CA : Public Library of Science, [2005]-) pp. e1007219- - issn: 1553-734X - wos: WOS:000507310800032 (7) - scopus: 2-s2.0-85077404153 (11)

11573/1270703 - 2019 - A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies
Montioli, Riccardo; Battini, Roberta; Paiardini, Alessandro; Tolve, Manuela; Bertoldi, Mariarita; Carducci, Carla; Leuzzi, Vincenzo; Borri Voltattorni, Carla - 01a Articolo in rivista
rivista: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. - - issn: 1096-7192 - wos: WOS:000473555500004 (18) - scopus: 2-s2.0-85065612038 (18)

11573/1273070 - 2019 - R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features
Montioli, Riccardo; Paiardini, Alessandro; Giardina, Giorgio; Zanzoni, Serena; Cutruzzola, Francesca; Cellini, Barbara; Borri Voltattorni, Carla - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000476663500011 (8) - scopus: 2-s2.0-85064506502 (9)

11573/1349570 - 2019 - Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation.
Traversa, A; Bernardo, S; Paiardini, A; Giovannetti, A; Marchionni, E; Genovesi, Ml; Guadagnolo, D; Torres, B; Paolacci, S; Bernardini, L; Mazza, T; Carella, M; Caputo, V; Pizzuti, A - 01a Articolo in rivista
rivista: MOLECULAR GENETICS & GENOMIC MEDICINE ([Hoboken, NJ] : John Wiley & Sons, [2013]-) pp. - - issn: 2324-9269 - wos: WOS:000497878100001 (5) - scopus: 2-s2.0-85075459805 (5)

11573/1176633 - 2018 - A novel germline mutation in CDK4 codon 24 associated to familial melanoma
Bottillo, I; La Starza, Sonia Roberta; Radio, F C; Molica, C; Pedace, L; Pierini, T; De Bernardo, C; Stingeni, L; Bargiacchi, Sara; Paiardini, A; Janson, G; Mecucci, C; Grammatico, P - 01f Lettera, Nota
rivista: CLINICAL GENETICS (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 934-935 - issn: 0009-9163 - wos: WOS:000427471000027 (5) - scopus: 2-s2.0-85043995463 (5)

11573/1089335 - 2018 - Corrigendum to “Pyridoxine-5′-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g > A (P.·Arg116gln) mutation” [Mol. Genet. Metab. 122/1–2 (2017) 135–142]
Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01b Commento, Erratum, Replica e simili
rivista: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 359-359 - issn: 1096-7192 - wos: WOS:000453637800007 (2) - scopus: 2-s2.0-85043513164 (2)

11573/1143149 - 2018 - The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells
Giardina, Giorgio; Paone, Alessio; Tramonti, Angela; Lucchi, Roberta; Marani, Marina; Magnifico, Maria Chiara; Bouzidi, Amani; Pontecorvi, Valentino; Guiducci, Giulia; Zamparelli, Carlotta; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3238-3253 - issn: 1742-464X - wos: WOS:000443814200008 (27) - scopus: 2-s2.0-85052452668 (28)

11573/1176648 - 2018 - Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: A case report
Lu, J; Zhao, X; Paiardini, A; Lang, Y; Bottillo, I; Shao, L - 01a Articolo in rivista
rivista: BMC NEPHROLOGY (London: BioMed Central, 2000-) pp. 181- - issn: 1471-2369 - wos: WOS:000438997000005 (3) - scopus: 2-s2.0-85049898689 (4)

11573/1139413 - 2018 - Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa
Mantoni, Federico; Paiardini, Alessandro; Brunotti, Paolo; D'angelo, Cecilia; Cervoni, Laura; Paone, Alessio; Cappellacci, Loredana; Petrelli, Riccardo; Ricciutelli, Massimo; Leoni, Livia; Rampioni, Giordano; Arcovito, Alessandro; Rinaldo, Serena; Cutruzzolà, Francesca; Giardina, Giorgio - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3815-3834 - issn: 1742-464X - wos: WOS:000447880900011 (23) - scopus: 2-s2.0-85052825956 (26)

11573/1176644 - 2018 - Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii
Maresi, E; Janson, G; Fruncillo, S; Paiardini, A; Vallone, Roberto; Dominici, P; Astegno, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 2111- - issn: 1661-6596 - wos: WOS:000442807400290 (10) - scopus: 2-s2.0-85050592702 (10)

11573/1115382 - 2018 - Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations
Montioli, Riccardo; Janson, Giacomo; Paiardini, Alessandro; Bertoldi, Mariarita; Borri Voltattorni, Carla - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 215-223 - issn: 1521-6543 - wos: WOS:000426066800005 (9) - scopus: 2-s2.0-85042453702 (9)

11573/1151881 - 2018 - A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa
Paiardini, A.; Mantoni, F.; Giardina, G.; Paone, A.; Janson, G.; Leoni, L.; Rampioni, G.; Cutruzzolà, F.; Rinaldo, S. - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0887-3585 - wos: WOS:000450353600008 (26) - scopus: 2-s2.0-85052809619 (28)

11573/1176640 - 2018 - Cysteine 180 is a redox sensor modulating activity of human pyridoxal 5'-phosphate histidine decarboxylase
Rossignoli, G; Grottesi, A; Bisello, G; Montioli, R; Borri Voltattorni, C; Paiardini, A; Bertoldi, M. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. - - issn: 0006-2960 - wos: WOS:000449722300009 (4) - scopus: 2-s2.0-85056239838 (4)

11573/1131469 - 2018 - Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes
Tramonti, Angela; Paiardini, Alessandro; Paone, Alessio; Bouzidi, Amani; Giardina, Giorgio; Guiducci, Giulia; Magnifico, Maria Chiara; Rinaldo, Serena; Mcdermott, Lee; Menendez, Javier A.; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 71-79 - issn: 0003-9861 - wos: WOS:000442192500007 (14) - scopus: 2-s2.0-85049429016 (13)

11573/952945 - 2017 - Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii
Astegno, Alessandra; Maresi, Elena; Bertoldi, Mariarita; La Verde, Valentina; Paiardini, Alessandro; Dominici, Paola - 01a Articolo in rivista
rivista: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 939-955 - issn: 0264-6021 - wos: WOS:000395819600006 (19) - scopus: 2-s2.0-85016139429 (19)

11573/952949 - 2017 - Identification of small molecule inhibitors of the aurora-A/TPX2 complex
Asteriti, Italia Anna; Daidone, F; Colotti, G; Rinaldo, Serena; Lavia, P; Guarguaglini, Giulia; Paiardini, Alessandro - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. - - issn: 1949-2553 - wos: WOS:000401003200118 (21) - scopus: 2-s2.0-85019153604 (22)

11573/1015066 - 2017 - Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis
Brusotti, Gloria; Montanari, Roberta; Capelli, Davide; Cattaneo, Giulia; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Peiretti, Franck; Bonardo, Bernadette; Paiardini, Alessandro; Calleri, Enrica; Pochetti, Giorgio - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 5777- - issn: 2045-2322 - wos: WOS:000405746500088 (58) - scopus: 2-s2.0-85024485998 (63)

11573/954375 - 2017 - Glucose metabolism in the progression of prostate cancer
Cutruzzola', Francesca; Giardina, Giorgio; Marani, Marina; Macone, Alberto; Paiardini, Alessandro; Rinaldo, Serena; Paone, Alessio - 01a Articolo in rivista
rivista: FRONTIERS IN PHYSIOLOGY (Lausanne: Frontiers Research Foundation, 2010-) pp. 97- - issn: 1664-042X - wos: WOS:000394487500001 (97) - scopus: 2-s2.0-85014162527 (105)

11573/1023679 - 2017 - Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ
Di Matteo, A; Franceschini, M; Paiardini, A; Grottesi, A; Chiarella, S; Rocchio, S; Di Natale, C; Marasco, D; Vitagliano, L; Travaglini-Allocatelli, C; Federici, L. - 01a Articolo in rivista
rivista: ONCOGENESIS (London Nature Publishing Group) pp. e379- - issn: 2157-9024 - wos: WOS:000415010100004 (14) - scopus: 2-s2.0-85032725431 (15)

11573/1014987 - 2017 - Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO)
Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01a Articolo in rivista
rivista: DATA IN BRIEF (New York : Elsevier Inc.) pp. 868-875 - issn: 2352-3409 - wos: WOS:000453415100125 (12) - scopus: 2-s2.0-85032823566 (12)

11573/1001903 - 2017 - Pyridoxine-5'-phosphate oxidase (pnpo) deficiency. clinical and biochemical alterations associated with the c.347g>a (pp. arg116gln) mutation
Di Salvo, Martino Luigi; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01a Articolo in rivista
rivista: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 1-8 - issn: 1096-7192 - wos: WOS:000413134800019 (28) - scopus: 2-s2.0-85030540261 (29)

11573/1010852 - 2017 - Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis
Giardina, Giorgio; Paiardini, Alessandro; Montioli, Riccardo; Cellini, Barbara; Voltattorni, Carla Borri; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11704- - issn: 2045-2322 - wos: WOS:000410859400036 (14) - scopus: 2-s2.0-85029469719 (14)

11573/932336 - 2017 - PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL
Janson, Giacomo; Zhang, Chengxin; Prado, Maria Giulia; Paiardini, Alessandro - 01a Articolo in rivista
rivista: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. 444-446- - issn: 1367-4803 - wos: WOS:000397260800021 (111) - scopus: 2-s2.0-85019233554 (117)

11573/952944 - 2017 - New insights emerging from recent investigations on Human Group II pyridoxal 5'-phosphate decarboxylases
Paiardini, Alessandro; Giardina, Giorgio; Rossignoli, Giada; Voltattorni, Carla Borri; Bertoldi, Mariarita - 01a Articolo in rivista
rivista: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 226-244 - issn: 0929-8673 - wos: WOS:000396017300001 (13) - scopus: 2-s2.0-85013635549 (12)

11573/1020398 - 2017 - Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases
Rinaldo, S.; Giardina, G.; Mantoni, F.; Paiardini, A.; Paone, Alessio; Cutruzzolã , Francesca - 02a Capitolo o Articolo
libro: c-di-GMP signaling - (978-1-4939-7239-5; 978-1-4939-7240-1)

11573/931868 - 2016 - Prediction and visualization data for the interpretation of sarcomeric and non-sarcomeric DNA variants found in patients with hypertrophic cardiomyopathy
Bottillo, Irene; D'angelantonio, Daniela; Caputo, Viviana; Paiardini, Alessandro; Lipari, Martina; De Bernardo, Carmelilia; Majore, Silvia; Castori, Marco; Zachara, Elisabetta; Re, Federica; Grammatico, Paola - 01a Articolo in rivista
rivista: DATA IN BRIEF (New York : Elsevier Inc.) pp. 607-613 - issn: 2352-3409 - wos: WOS:000453166200095 (0) - scopus: 2-s2.0-84962574347 (0)

11573/952939 - 2016 - Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions
Drinkwater, Nyssa; Vinh, Natalie B.; Mistry, Shailesh N.; Bamert, Rebecca S.; Ruggeri, Chiara; Holleran, John P.; Loganathan, Sasdekumar; Paiardini, Alessandro; Charman, Susan A.; Powell, Andrew K.; Avery, Vicky M.; Mcgowan, Sheena; Scammells, Peter J. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 43-64 - issn: 0223-5234 - wos: WOS:000371650900004 (42) - scopus: 2-s2.0-84955290142 (41)

11573/832010 - 2016 - In silico discovery and in vitro validation of catechol-containing sulfonohydrazide compounds as potent inhibitors of the diguanylate cyclase PleD
Fernicola, Silvia; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Leoni, Livia; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 147-156 - issn: 0021-9193 - wos: WOS:000366587800006 (30) - scopus: 2-s2.0-84953898134 (39)

11573/845279 - 2016 - A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells
Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4570-4583 - issn: 1949-2553 - wos: WOS:000369952400069 (44) - scopus: 2-s2.0-84958012663 (43)

11573/1023676 - 2016 - The novel R347G pathogenic mutation of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency
Montioli, Riccardo; Paiardini, Alessandro; Kurian, Manju A.; Dindo, Mirco; Rossignoli, Giada; Heales, Simon J. R.; Pope, Simon; Voltattorni, Carla Borri; Bertoldi, Mariarita - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 676-682 - issn: 1570-9639 - wos: WOS:000374806200004 (17) - scopus: 2-s2.0-84962074484 (16)

11573/894263 - 2016 - Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
Paiardini, Alessandro; Tramonti, Angela; Schirch, Doug; Guiducci, Giulia; Di Salvo, Martino Luigi; Fiascarelli, Alessio; Giorgi, Alessandra; Maras, Bruno; Cutruzzola', Francesca; Contestabile, Roberto - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1506-1517 - issn: 1570-9639 - wos: WOS:000383935100005 (37) - scopus: 2-s2.0-84982202451 (36)

11573/982304 - 2016 - Genotype-phenotype correlation study through protein model of 3- methylcrotonyl-CoA carboxylase
Tolve, Manuela; Paiardini, Alessandro; Janson, Giacomo; Artiola, Cristiana; Scarno, G; Giovanniello, Teresa; Pasquali, Amelia; Angeloni, Antonio; Carducci, Claudia; Leuzzi, Vincenzo; Carducci, Carla - 04c Atto di convegno in rivista
rivista: JOURNAL OF INHERITED METABOLIC DISEASE (Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 79-79 - issn: 0141-8955 - wos: (0) - scopus: (0)

11573/845848 - 2015 - Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy.
Bottillo, Irene; D'angelantonio, Daniela; Caputo, Viviana; Paiardini, Alessandro; Lipari, Martina; De Bernardo, C; Giannarelli, D; Pizzuti, Antonio; Majore, S; Castori, M; Zachara, E; Re, F; Grammatico, Paola - 01a Articolo in rivista
rivista: GENE (Amsterdam Netherlands: Elsevier BV) pp. 227-235 - issn: 0378-1119 - wos: WOS:000369191500017 (27) - scopus: 2-s2.0-84952864713 (31)

11573/808531 - 2015 - X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17
Drinkwater, Nyssa; Bamert, Rebecca S.; Sivaraman, Komagal Kannan; Paiardini, Alessandro; Mcgowan, Sheena - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 789-795 - issn: 0887-3585 - wos: WOS:000351520400018 (12) - scopus: 2-s2.0-84925332596 (12)

11573/832011 - 2015 - Synthesis of triazole-linked analogues of c-di-gmp and their interactions with diguanylate cyclase
Fernicola, Silvia; Torquati, Ilaria; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Messina, Marco; Leoni, Livia; Del Bello, Fabio; Petrelli, Riccardo; Rinaldo, Serena; Cappellacci, Loredana; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8269-8284 - issn: 0022-2623 - wos: WOS:000363915600025 (30) - scopus: 2-s2.0-84945345287 (35)

11573/780499 - 2015 - How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; Di Salvo, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000352226400005 (74) - scopus: 2-s2.0-84964265516 (79)

11573/808565 - 2015 - Screening the medicines for malaria venture "malaria box" against the Pasmodium falciparum aminopeptidases, m1, m17 and m18
Paiardini, Alessandro; Bamert, Rebecca S.; Kannan Sivaraman, Komagal; Drinkwater, Nyssa; Mistry, Shailesh N.; Scammells, Peter J.; Mcgowan, Sheena - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0115859- - issn: 1932-6203 - wos: WOS:000349789800004 (34) - scopus: 2-s2.0-84923667053 (36)

11573/780502 - 2015 - Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase
Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 490-497 - issn: 1860-7179 - wos: WOS:000350456200006 (28) - scopus: 2-s2.0-84923349870 (29)

11573/781589 - 2015 - Structural basis of functional diversification of the HD-GYP domain revealed by the pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site
Rinaldo, Serena; Paiardini, Alessandro; Stelitano, Valentina; Brunotti, Paolo; Cervoni, Laura; Fernicola, Silvia; Protano, Carmela; Vitali, Matteo; Cutruzzola', Francesca; Giardina, Giorgio - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1525-1535 - issn: 0021-9193 - wos: WOS:000351738600021 (28) - scopus: 2-s2.0-84930786571 (30)

11573/808580 - 2015 - Identification and validation of a potent dual Inhibitor of the P. falciparum M1 and M17 aminopeptidases using virtual screening
Ruggeri, Chiara; Drinkwater, Nyssa; Sivaraman, Komagal Kannan; Bamert, Rebecca S; Mcgowan, Sheena; Paiardini, Alessandro - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0138957- - issn: 1932-6203 - wos: WOS:000361800700129 (19) - scopus: 2-s2.0-84947227435 (19)

11573/557449 - 2014 - On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase
Di Salvo, Martino Luigi; Remesh, Sg; Vivoli, Mirella; Ghatge, Ms; Paiardini, Alessandro; D'aguanno, S; Safo, Mk; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 129-145 - issn: 1742-464X - wos: WOS:000330591100011 (60) - scopus: 2-s2.0-84891832957 (62)

11573/556744 - 2014 - Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis
Itamar, Kass; David E., Hoke; M. G. S., Costa; Cyril F., Reboul; B. T., Porebski; N. P., Cowieson; Herve, Leh; Pennacchietti, Eugenia; J., Mccoey; Oded, Kleifeld; Carla Borri, Voltattorni; David, Langley; Brendan, Roome; Ian R., Mackay; Daniel, Christ; David, Perahia; M., Buckle; Paiardini, Alessandro; De Biase, Daniela; A. M., Buckle - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. E2524-E2529 - issn: 0027-8424 - wos: WOS:000337760600005 (32) - scopus: 2-s2.0-84903461226 (34)

11573/739204 - 2014 - Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors.
Mistry, Sn; Drinkwater, N; Ruggeri, Chiara; Sivaraman, Kk; Loganathan, S; Fletcher, S; Drag, M; Paiardini, Alessandro; Avery, Vm; Scammells, Pj; Mcgowan, S. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. - - issn: 0022-2623 - wos: WOS:000344977400035 (46) - scopus: 2-s2.0-84923775047 (47)

11573/1681788 - 2014 - PLP-dependent enzymes
Paiardini, A.; Contestabile, R.; Buckle, A. M.; Cellini, B. - 01a Articolo in rivista
rivista: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. - - issn: 2314-6133 - wos: WOS:000330527900001 (11) - scopus: 2-s2.0-84893776886 (11)

11573/557925 - 2014 - PLP-dependent enzymes.
Paiardini, Alessandro; Contestabile, Roberto; Buckle, Am; Cellini, B. - 01a Articolo in rivista
rivista: BIOMED RESEARCH INTERNATIONAL (London: Hindawi, [2001]-) pp. Article ID 856076-Article ID 856076 - issn: 2314-6141 - wos: WOS:000330527900001 (11) - scopus: 2-s2.0-84893776886 (11)

11573/542045 - 2014 - The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.
Paiardini, Alessandro; P., Aducci; Cervoni, Laura; Cutruzzola', Francesca; C. D., Lucente; Janson, Giacomo; Pascarella, Stefano; Rinaldo, Serena; S., Visconti; L., Camoni - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 52-62 - issn: 1521-6543 - wos: WOS:000331299000008 (24) - scopus: 2-s2.0-84893774983 (24)

11573/618583 - 2014 - SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. e1525- - issn: 2041-4889 - wos: WOS:000345643900019 (90) - scopus: 2-s2.0-84923383679 (91)

11573/514722 - 2013 - The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
Davide, Antoniani; Elio, Rossi; Rinaldo, Serena; Paola, Bocci; Marco, Lolicato; Paiardini, Alessandro; Nadia, Raffaelli; Cutruzzola', Francesca; Paolo, Landini - 01a Articolo in rivista
rivista: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (Germany: Springer Verlag Germany:Tiergartenstrasse) pp. 7325-7336 - issn: 0175-7598 - wos: WOS:000322408100024 (60) - scopus: 2-s2.0-84881232457 (71)

11573/513451 - 2013 - Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection
Di Salvo, Martino Luigi; Contestabile, Roberto; Paiardini, Alessandro; Maras, Bruno - 01a Articolo in rivista
rivista: MEDICAL HYPOTHESES (-CHURCHILL LIVINGSTONE, JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH, SCOTLAND, MIDLOTHIAN, EH1 3AF -Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 633-636 - issn: 0306-9877 - wos: WOS:000317995000028 (53) - scopus: 2-s2.0-84875616592 (53)

11573/501940 - 2013 - Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity
Di Salvo, Martino Luigi; Florio, Rita; Paiardini, Alessandro; Vivoli, Mirella; Simona, D'aguanno; Contestabile, Roberto - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 55-65 - issn: 0003-9861 - wos: WOS:000314388900001 (33) - scopus: 2-s2.0-84871911425 (32)

11573/525771 - 2013 - Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications
E., Oppici; K., Fodor; Paiardini, Alessandro; C., Williams; C. B., Voltattorni; M., Wilmanns; B., Cellini - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1457-1465 - issn: 0887-3585 - wos: WOS:000329220400015 (22) - scopus: 2-s2.0-84880700894 (21)

11573/534127 - 2013 - Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: Clues from the structure of the catalytic domain
Giardina, Giorgio; Paiardini, Alessandro; Fernicola, Silvia; Stefano, Franceschini; Rinaldo, Serena; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e81324- - issn: 1932-6203 - wos: WOS:000327541700059 (36) - scopus: 2-s2.0-84896718101 (40)

11573/525772 - 2013 - Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum.
Kannan Sivaraman, K; Paiardini, Alessandro; Sieńczyk, M; Ruggeri, Chiara; Oellig, Ca; Dalton, Jp; Scammells, Pj; Drag, M; Mcgowan, S. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5213-5217 - issn: 0022-2623 - wos: WOS:000321237100032 (57) - scopus: 2-s2.0-84879558016 (56)

11573/528747 - 2013 - Type I pyridoxal 5'-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines.
Milano, Teresa; Paiardini, Alessandro; Grgurina, Ingeborg; Pascarella, Stefano - 01a Articolo in rivista
rivista: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 1-31 - issn: 1472-6807 - wos: WOS:000329231800001 (16) - scopus: 2-s2.0-84885991881 (19)

11573/515471 - 2013 - Structural mimicry between SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: insights from an in silico study
Paiardini, Alessandro; Pascarella, Stefano - 01a Articolo in rivista
rivista: THEORETICAL BIOLOGY AND MEDICAL MODELLING (London : BioMed Central, 2004-) pp. 25- - issn: 1742-4682 - wos: WOS:000318074400001 (12) - scopus: 2-s2.0-84875956630 (16)

11573/434272 - 2013 - Chemogenomics of pyridoxal 5'-phosphate dependent enzymes.
Singh, R; Spyrakis, F; Cozzini, P; Paiardini, Alessandro; Pascarella, Stefano; Mozzarelli, A. - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 183-194 - issn: 1475-6366 - wos: WOS:000313663400023 (12) - scopus: 2-s2.0-84874162455 (11)

11573/525774 - 2013 - C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG
Stelitano, Valentina; Giardina, Giorgio; Paiardini, Alessandro; Castiglione, Nicoletta; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e74920- - issn: 1932-6203 - wos: WOS:000324494000139 (46) - scopus: 2-s2.0-84884194723 (50)

11573/501033 - 2012 - Rapid profiling of disease alleles using a tunable reporter of protein misfolding
A. M. C., Pittman; M. D., Lage; V., Poltoratsky; J. D., Vrana; Paiardini, Alessandro; A., Roncador; B., Cellini; R. M., Hughes; C. L., Tucker - 01a Articolo in rivista
rivista: GENETICS (Genetics Society of America:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7029, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728) pp. 831-842 - issn: 0016-6731 - wos: WOS:000310793900005 (17) - scopus: 2-s2.0-84869077214 (20)

11573/434078 - 2012 - Molecular insights into primary hyperoxaluria type i pathogenesis
Barbara, Cellini; E., Oppici; Paiardini, Alessandro; R., Montioli - 01a Articolo in rivista
rivista: FRONTIERS IN BIOSCIENCE (Frontiers in Bioscience:PO Box 160:Albertson, NY 11507:(516)484-2831, (516)484-0813, EMAIL: fbsadmin@bioscience.org, INTERNET: http://www.bioscience.org, Fax: (516)484-2831) pp. 621-634 - issn: 1093-9946 - wos: WOS:000300049600015 (25) - scopus: 2-s2.0-84860351331 (29)

11573/446775 - 2012 - PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL
Bramucci, Emanuele; Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
rivista: BMC BIOINFORMATICS ([London]: BioMed Central, [2000]-) pp. S2- - issn: 1471-2105 - wos: WOS:000303936400003 (143) - scopus: 2-s2.0-84864192056 (147)
congresso: 8th Annual Meeting of the Italian-Society-of-Bioinformatics (BITS) (Pisa, ITALY)

11573/442251 - 2012 - Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors
Daidone, Frederick; Riccardo, Montioli; Paiardini, Alessandro; Barbara, Cellini; Antonio, Macchiarulo; Giardina, Giorgio; Bossa, Francesco; Carla Borri, Voltattorni - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e31610-e31610 - issn: 1932-6203 - wos: WOS:000302916100026 (54) - scopus: 2-s2.0-84857609756 (60)

11573/499750 - 2012 - Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine-Thr3 from Streptomyces sp OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR
Fullone, Maria Rosaria; Paiardini, Alessandro; Miele, Rossella; Marsango, Sara; Dennis C., Gross; Satoshi, Omura; Enric Ros, Herrera; Bonaccorsi Di Patti, Maria Carmela; Lagana', Aldo; Pascarella, Stefano; Grgurina, Ingeborg - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4269-4282 - issn: 1742-464X - wos: WOS:000311432900002 (14) - scopus: 2-s2.0-84870062977 (14)

11573/406527 - 2011 - PyMod: a tool for the analysis of protein structures and sequences in PyMOL
Bramucci, Emanuele; Paiardini, Alessandro; Pascarella, Stefano - 04d Abstract in atti di convegno
congresso: BITS Annual meeting 2011 (Pisa)

11573/377566 - 2011 - In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Daidone, Frederick; Florio, Rita; Rinaldo, Serena; Contestabile, Roberto; Di Salvo, Martino Luigi; Cutruzzola', Francesca; Bossa, Francesco; Paiardini, Alessandro - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1616-1621 - issn: 0223-5234 - wos: WOS:000289655100017 (50) - scopus: 2-s2.0-79953228534 (53)

11573/389297 - 2011 - IDENTIFICATION BY VIRTUAL SCREENING AND IN VITRO TESTING OF NOVEL HUMAN DOPA DECARBOXYLASE INHIBITORS
F., Daidone; R., Montioli; Paiardini, Alessandro; B., Cellini; A., Macchiarulo; Giardina, Giorgio; Bossa, Francesco; C., Borri Voltattorni - 04d Abstract in atti di convegno
congresso: FEBS Congress 2011 (Torino)

11573/409570 - 2011 - Molecular cloning of the biosynthetic cluster involved in the production of 4-chlorothreonine in Streptomyces sp. OH-5093: insight into the structure-activity relationship of a new nonheme Fe(II) halogenase
Fullone, Maria Rosaria; Miele, Rossella; Bonaccorsi Di Patti, Maria Carmela; E., Ros Herrera; L., Pirone; L., Cattaneo; Marsango, Sara; Paiardini, Alessandro; Grgurina, Ingeborg - 04a Atto di comunicazione a congresso
congresso: Nature Aided Drug Discovery (NADD) (Napoli)

11573/410615 - 2011 - Crystal structure of the apo form of human aromatic L-amino acid decarboxylase: an open conformation unveils novel insights into the mechanism of PLP addition to the apoenzymes of group II decarboxylases
Giardina, Giorgio; Montioli, R.; Gianni, Stefano; Cellini, B.; Paiardini, Alessandro; Voltattorni, Cb; Cutruzzola', Francesca - 04d Abstract in atti di convegno
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 263-263 - issn: 1742-464X - wos: WOS:000292333102058 (0) - scopus: (0)
congresso: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/426205 - 2011 - Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
Giardina, Giorgio; R., Montioli; Gianni, Stefano; B., Cellini; Paiardini, Alessandro; C., Borri Voltattorni; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 20514-20519 - issn: 0027-8424 - wos: WOS:000298289400055 (88) - scopus: 2-s2.0-84855517335 (86)

11573/389117 - 2011 - IN SILICO AND IN VITRO VALIDATION OF SERINE HYDROXYMETHYLTRANSFERASE AS A CHEMOTHERAPEUTIC TARGET OF THE ANTIFOLATE DRUG PEMETREXED.
Paiardini, Alessandro - 04d Abstract in atti di convegno
congresso: Febs Congress 2011 (Torino)

11573/224845 - 2011 - Bioinformatica: dalla sequenza alla struttura delle proteine
Pascarella, Stefano; Paiardini, Alessandro - 03a Saggio, Trattato Scientifico

11573/406542 - 2011 - Structural adaptation of enzymes from halophilic organisms
Siglioccolo, Alessandro; Paiardini, Alessandro; M., Piscitelli; Pascarella, Stefano - 04d Abstract in atti di convegno
congresso: BITS annual meeting 2011 (Pisa)

11573/433699 - 2011 - Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface
Siglioccolo, Alessandro; Paiardini, Alessandro; Maria, Piscitelli; Pascarella, Stefano - 01a Articolo in rivista
rivista: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 50- - issn: 1472-6807 - wos: WOS:000301202900001 (113) - scopus: 2-s2.0-84055213697 (125)

11573/389443 - 2010 - MOLECULAR DEFECTS OF THE GLYCINE 41 VARIANTS OF ALANINE:GLYOXYLATE AMINOTRANSFERASE ASSOCIATED WITH PRIMARY HYPEROXALURIA TYPE I
B., Cellini; R., Montioli; Paiardini, Alessandro; A., Lorenzetto; F., Maset; T., Bellini; E., Oppici; C., Borri Voltattorni - 04d Abstract in atti di convegno
congresso: Congresso Proteine 2010 (Parma)

11573/131782 - 2010 - Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I.
Cellini, B; Montioli, R; Paiardini, Alessandro; Lorenzetto, A; Maset, F; Bellini, T; Oppici, E; Voltattorni, Cb - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 2896-2901 - issn: 0027-8424 - wos: WOS:000274599500036 (62) - scopus: 2-s2.0-77649267180 (61)

11573/389445 - 2010 - COMPUTER-AIDED DRUG DESIGN OF COMPETITIVE INHIBITORS OF L-DOPA-DECARBOXYLASE, A TARGET FOR THE TREATMENT OF PARKINSON'S DISEASE
F., Daidone; R., Montioli; Paiardini, Alessandro; A., Macchiarulo; Pascarella, Stefano; R., Pellicciari; C., Voltattorni; F., Bossa - 04d Abstract in atti di convegno
congresso: Congresso Proteine 2010 (Parma)

11573/228709 - 2010 - Expression of Bv8 in pichia pastoris to identify structural features for receptor binding
Miele, Rossella; Lattanzi, Roberta; Bonaccorsi Di Patti, Maria Carmela; Paiardini, Alessandro; Negri, Lucia; Barra, Donatella - 01a Articolo in rivista
rivista: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. 10-14 - issn: 1046-5928 - wos: WOS:000279312700002 (15) - scopus: 2-s2.0-77955428111 (15)

11573/389648 - 2010 - A CHEMOGENOMIC APPROACH TO THE DEVELOPMENT OF SPECIFIC LIGANDS FOR PLP-DEPENDENT ENZYMES
R., Singh; Paiardini, Alessandro; B., Campanini; F., Spyrakis; P., Cozzini; C., Giunta; A., Mozzarelli - 04d Abstract in atti di convegno
congresso: Congresso Proteine 2010 (Parma)

11573/145268 - 2009 - Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation.
Cellini, B; Montioli, R; Paiardini, Alessandro; Lorenzetto, A; Borri Voltattorni, C. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 8349-8358 - issn: 0021-9258 - wos: WOS:000264397800019 (51) - scopus: 2-s2.0-67649732393 (52)

11573/362128 - 2009 - Structural stability of the cofactor binding site in Escherichia coli serine hydroxymethyltransferase--the role of evolutionarily conserved hydrophobic contacts.
Florio, Rita; Chiaraluce, Roberta; Consalvi, Valerio; Paiardini, Alessandro; Catacchio, B; Bossa, Francesco; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 7319-7328 - issn: 1742-464X - wos: WOS:000272172600011 (3) - scopus: 2-s2.0-71949091428 (3)

11573/362968 - 2009 - The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
Florio, Rita; Chiaraluce, Roberta; Consalvi, Valerio; Paiardini, Alessandro; Catacchio, B; Bossa, Francesco; Contestabile, Roberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 132-143 - issn: 1742-464X - wos: WOS:000261683900012 (13) - scopus: 2-s2.0-57649153157 (13)

11573/145270 - 2009 - An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme.
Montioli, R; Cellini, B; Bertoldi, M; Paiardini, Alessandro; Voltattorni, Cb - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 301-317 - issn: 0887-3585 - wos: WOS:000262100800003 (9) - scopus: 2-s2.0-59449102837 (8)

11573/230259 - 2009 - Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): Molecular modeling and surface analysis by computational methods and limited proteolysis
V., Severino; Paiardini, Alessandro; Pascarella, Stefano; A., Parente; A., Chambery - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (-Attuale :ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE -Butterworth Heinemann Publishers:Linacre House Jordan Hill, Oxford OX2 8DP United Kingdom:011 44 1865 314569, EMAIL: bhmarketing@repp.co.uk, INTERNET: http://www.laxtonsprices.co.uk, Fax: 011 44 1865 314569) pp. 407-413 - issn: 0141-8130 - wos: WOS:000271052400014 (3) - scopus: 2-s2.0-70149106350 (3)

11573/145267 - 2008 - Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: Spectroscopic and kinetic analysis
Bertoldi, M; Cellini, B; Paiardini, Alessandro; Montioli, R; Borri Voltattorni, C. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1356-1362 - issn: 1570-9639 - wos: WOS:000259388800029 (4) - scopus: 2-s2.0-53149086699 (4)

11573/145265 - 2008 - Insights into the interaction of sortilin with proneurotrophins: A computational approach
Paiardini, Alessandro; Caputo, Viviana - 01a Articolo in rivista
rivista: NEUROPEPTIDES (Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 205-214 - issn: 0143-4179 - wos: WOS:000254779400009 (17) - scopus: 2-s2.0-39849110118 (20)

11573/227624 - 2008 - "Hot cores" in proteins: Comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms
Paiardini, Alessandro; Riccardo, Sali; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
rivista: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 14-31 - issn: 1472-6807 - wos: WOS:000255177300002 (18) - scopus: 2-s2.0-42149186292 (18)

11573/145263 - 2007 - Human wild-type alanine : glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications
Barbara, Cellini; Mariarita, Bertoldi; Riccardo, Montioli; Paiardini, Alessandro; Carla, Borri Voltattorni - 01a Articolo in rivista
rivista: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 39-50 - issn: 0264-6021 - wos: WOS:000250951800005 (89) - scopus: 2-s2.0-36349021899 (91)

11573/235513 - 2007 - Mutational analysis and homology modelling of SyrC, the aminoacyltransferase in the biosynthesis of syringomycin
Fullone, Maria Rosaria; Paiardini, Alessandro; Dennis C., Gross; Shi En, Lu; Alberto, Fiore; Grgurina, Ingeborg - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 201-207 - issn: 0006-291X - wos: WOS:000251021100002 (3) - scopus: 2-s2.0-35448942727 (3)

11573/145262 - 2006 - Dimerization and folding processes of Treponema denticola cystalysin: the role of pyridoxal 5'-phosphate.
Cellini, B; Bertoldi, M; Montioli, R; Laurents D., V; Paiardini, Alessandro; Voltattorni, Cb - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 14140-14154 - issn: 0006-2960 - wos: WOS:000242179100022 (18) - scopus: 2-s2.0-33751560419 (20)

11573/389114 - 2006 - PLP-dependent enzymes: new answers to old questions
Paiardini, Alessandro - 04a Atto di comunicazione a congresso
congresso: Proteins in Rome (Roma)

11573/1314736 - 2006 - "Hot cores": comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms
Paiardini, Alessandro; Sali, Riccardo; Pascarella, Stefano - 04d Abstract in atti di convegno
congresso: Proteine 2006 (Novara)
libro: Protyeine 2006: ATTI - ()

11573/145261 - 2006 - A 3D model of Reelin subrepeat regions predicts Reelin binding to carbohydrates
Roger, Panteri; Paiardini, Alessandro; Flavio, Keller - 01a Articolo in rivista
rivista: BRAIN RESEARCH (Amsterdam; Lausanne; New York; Oxford; Shannon; Tokyo: Elsevier) pp. 222-230 - issn: 0006-8993 - wos: WOS:000241793900027 (9) - scopus: 2-s2.0-33749347872 (10)

11573/235852 - 2005 - CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 50-55 - issn: 0305-1048 - wos: WOS:000230271400008 (22) - scopus: 2-s2.0-23144434732 (22)

11573/144415 - 2004 - Site-directed mutagenesis provides insight into racemization and transamination of alanine catalyzed by Treponema denticola cystalysin
B., Cellini; M., Bertoldi; Paiardini, Alessandro; S., D'aguanno; C. B., Voltattorni - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 36898-36905 - issn: 0021-9258 - wos: WOS:000223453600092 (11) - scopus: 2-s2.0-4344706396 (12)

11573/389112 - 2004 - ENZIMI PIRIDOSSAL-5’-DIPENDENTI: UN PARADIGMA DI VERSATILITA’ STRUTTURALE
Paiardini, Alessandro - 04a Atto di comunicazione a congresso
congresso: Seminari Centro di Eccellenza di Biologia e Medicina Sperimentale (BEMM) (Roma)

11573/236607 - 2004 - Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5'-phosphate-dependent enzymes
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 2992-3005 - issn: 0961-8368 - wos: WOS:000224762800016 (34) - scopus: 2-s2.0-7244238406 (33)

11573/389987 - 2004 - Structurally conserved regions and hydrophobic contacts in the fold type I, PLP-dependent enzymes
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
rivista: ITALIAN JOURNAL OF BIOCHEMISTRY (Il Pensiero Scientifico) pp. 18-18 - issn: 0021-2938 - wos: (0) - scopus: (0)
congresso: Proteine 2004 (Viterbo)

11573/254540 - 2003 - Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications
Mariarita, Bertoldi; Barbara, Cellini; Paiardini, Alessandro; Di Salvo, Martino Luigi; Carla Borri, Voltattorni - 01a Articolo in rivista
rivista: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 473-483 - issn: 0264-6021 - wos: WOS:000182437200026 (18) - scopus: 2-s2.0-0038302704 (19)

11573/251097 - 2003 - Threonine aldolase and alanine racemase: novel examples of convergent evolution in the superfamily of vitamin B6-dependent enzymes
Paiardini, Alessandro; Contestabile, Roberto; D'aguanno, Simona; Pascarella, Stefano; Bossa, Francesco - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214-219 - issn: 0006-3002 - wos: WOS:000182549400037 (27) - scopus: 2-s2.0-0037974655 (32)

11573/406700 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferase
Paiardini, Alessandro; Gianese, G.; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 105-105 - issn: 0961-8368 - wos: (0) - scopus: (0)
congresso: Fifth European Symposium of the Protein Society (Firenze)

11573/1307047 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferases
Paiardini, Alessandro; Gianese, Giulio; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
rivista: ITALIAN JOURNAL OF BIOCHEMISTRY (Il Pensiero Scientifico) pp. 55-55 - issn: 0021-2938 - wos: (0) - scopus: 2-s2.0-0041733553 (3)
congresso: SIB-BIB 2003 (Milano)

11573/254004 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferase
Paiardini, Alessandro; Gianese, Giulio; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 122-134 - issn: 0887-3585 - wos: WOS:000180131100012 (26) - scopus: 2-s2.0-0037236096 (32)

11573/399901 - 2003 - A strategy for detection of structural conserved regions and contacts in protein superfamilies: application to the PLP-dependent enzymes
Paiardini, Alessandro; L., Di Vincenzo; Bossa, Francesco; Pascarella, Stefano - 04d Abstract in atti di convegno
congresso: European Conference on Computational Biology (Parigi)
libro: Proceeding of the European Conference on Computation Biology in conjunction with the French National Conference on Bioinformatics (JOBIM 2003) - ()

11573/410068 - 2002 - “L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functions”, in the 3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins, Southampton, United Kingdom, 14-19 April 2002.
Contestabile, Roberto; Paiardini, Alessandro; Pascarella, Stefano; Di Salvo, Martino Luigi; D'aguanno, S; Bossa, Francesco - 04a Atto di comunicazione a congresso
congresso: 3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins (Southampton, United Kingdom)

11573/1306916 - 2001 - L-threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase: structural diversity and uniformity in a subgroup of closely related enzymes catalysing different reactions
Contestabile, R.; Paiardini, A.; Pascarella, S.; Bossa, F. - 04c Atto di convegno in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 145-145 - issn: 0961-8368 - wos: (0) - scopus: (0)
congresso: Fourth European Symposium of the Protein society (Parigi)

11573/410266 - 2001 - COMUNICAZIONE ORALE A CONGRESSO SU INVITO “Studies on the evolutionary origins of pyridoxal-phosphate-dependent enzymes: catalytic promiscuity and reaction specificity”, in “Quo Vadis Proteomics”, Napoli, 26 Marzo 2001.
Contestabile, Roberto; Paiardini, Alessandro; Bossa, Francesco - 04a Atto di comunicazione a congresso

11573/248895 - 2001 - L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subsgroup of strictly related enzymes specialized for different functions
Contestabile, Roberto; Paiardini, Alessandro; Pascarella, Stefano; Di Salvo, Martino Luigi; D'aguanno, Simona; Bossa, Francesco - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 6508-6525 - issn: 0014-2956 - wos: WOS:000172788400020 (79) - scopus: 2-s2.0-0035666383 (85)

11573/399998 - 2001 - Structural adaptation of serine hydroxymethyltransferase to extreme environments
Paiardini, Alessandro; Pascarella, Stefano; Bossa, Francesco - 04d Abstract in atti di convegno
congresso: 4th International Conference on Molecular Structural Biology (Vienna)
libro: Proceeding of the 4th International Conference on Molecular Structural Biology - (9783900554323)

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