ALESSANDRO PAIARDINI

Associate professor


email: alessandro.paiardini@uniroma1.it
phone: 06/7027114
building: Dip Scienze Biochimiche
room: T01

Email Address: alessandro.paiardini@uniroma1.it

EDUCATION

2001 – Bachelor's degree with honors in Biology
2005 – PhD Thesis "Molecular Evolution of fold-type-I, PLP-dependent enzymes."
2006 – Post-Doctoral Fellowship (2 years)

PROFESSIONAL CAREER

2006 – Researcher (Permanent Position) SSD BIO/10 (05/E1)
2007 – IT Administration of Biological Sciences and Biochemistry websites
2015 – National Scientific Qualification PA Bio10 (05/E1)
2015 – National Scientific Qualification PA Bio11 (05/E2)
2017 – Associate Professor (Permanent Position) SSD BIO/10 (05/E1)
2017 – National Scientific Qualification PO Bio10 (05/E1)
2024 – President of the Degree Course in Bioinformatics

CURRENT TEACHING ACTIVITIES (2018/19)

2015 to date: Sapienza University of Rome - Module BIOINFORMATICS (SSD BIO/10; CFU:6) for the integrated course of BIOINFORMATICS AND PHARMACOLOGY (1041756) SSD BIO/10, BIO/14. CFU: 12 14456-Biotechnology [L (DM 270/04) - Ordin. 2010] - L-2 - Interfaculty Pharmacy and Medicine Sciences Mathematical, Physical, and Natural Sciences Medicine and Psychology - (Chair of the Integrated Course (CFU:12) in 2015)
2016 to date: Sapienza University of Rome - STRUCTURE BIOSYNTHESIS AND ANALYSIS OF PROTEINS SSD BIO/10. CFU: 6 28700- Genetics and Molecular Biology [L (DM 270/04)] - LM-6 - Mathematical, Physical, and Natural Sciences - (Chair of the Course in English CFU:6)
2017: Sapienza University of Rome - BIOCHEMISTRY I SSD BIO/10. CFU: 6 28613- Bioinformatics (L-2) Faculty of Pharmacy and Medicine – Information engineering, computer science, and statistics – Medicine and Dentistry - (Chair of the Course in English CFU:6)

AWARDS, HONORS, AND SCHOLARSHIPS

2017: Awarded with the "Eccellenza per la didattica" by the Faculty of Sciences at Sapienza University, appointed to the top 5% teachers of the Faculty, Rome
2010: Awarded with the "medaglia di rappresentanza" by the President of the Italian Republic, as Outstanding Young Researcher at Sapienza University, during the Young International Forum (YIF), Rome
2001: Awarded by the Interdepartmental Research Centre for Models and Information Analysis in Biomedical Systems for the best 2000/2001 Thesis

BIBLIOMETRIC DATA

ORCID ID: https://orcid.org/0000-0001-9078-7545 (SCOPUS database)
Total Publications: 125
Total Citations: 3000
H-index: 33

Research products

11573/1707348 - 2024 - Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctions
Amormino, C.; Russo, E.; Tedeschi, V.; Fiorillo, M. T.; Paiardini, A.; Spallotta, F.; Rosano, L.; Tuosto, L.; Kunkl, M. - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:001187533300001 (0) - scopus: 2-s2.0-85188131451 (0)

11573/1701072 - 2024 - Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase
Barile, Anna; Graziani, Claudio; Antonelli, Lorenzo; Parroni, Alessia; Fiorillo, Annarita; Di Salvo, Martino Luigi; Ilari, Andrea; Giorgi, Alessandra; Rosignoli, Serena; Paiardini, Alessandro; Contestabile, Roberto; Tramonti, Angela - 01a Articolo in rivista
paper: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:001146773300001 (2) - scopus: 2-s2.0-85182849034 (2)

11573/1720191 - 2024 - An inherited TBX3 alteration in a prenatal case of ulnar‐mammary syndrome: Clinical assessment and functional characterization in Drosophila melanogaster
Bottillo, Irene; D'alessandro, Andrea; Ciccone, Maria Pia; Cestra, Gianluca; Di Giacomo, Gianluca; Silvestri, Evelina; Castori, Marco; Brancati, Francesco; Lenzi, Andrea; Paiardini, Alessandro; Majore, Silvia; Cenci, Giovanni; Grammatico, Paola - 01a Articolo in rivista
paper: JOURNAL OF CELLULAR PHYSIOLOGY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-14 - issn: 0021-9541 - wos: WOS:001319932900001 (0) - scopus: 2-s2.0-85205253072 (0)

11573/1719569 - 2024 - The Z isomer of pyridoxilidenerhodanine 5′‐phosphate is an efficient inhibitor of human pyridoxine 5′‐phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target
Graziani, Claudio; Barile, Anna; Antonelli, Lorenzo; Fiorillo, Annarita; Ilari, Andrea; Vetica, Fabrizio; Di Salvo, Martino Luigi; Paiardini, Alessandro; Tramonti, Angela; Contestabile, Roberto - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4984-5001 - issn: 1742-464X - wos: WOS:001314568800001 (0) - scopus: 2-s2.0-85204241869 (0)

11573/1711262 - 2024 - AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach
Rosignoli, Serena; Lustrino, Elisa; Conci, Alessio; Fabrizi, Alessandra; Rinaldo, Serena; Latella, Mariacarmela; Enzo, Elena; Prosseda, Gianni; De Rosa, Laura; De Luca, Michele; Paiardini, Alessandro - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. W29-W38 - issn: 0305-1048 - wos: WOS:001230689400001 (0) - scopus: 2-s2.0-85197797884 (1)

11573/1707220 - 2024 - Making Use of Averaging Methods in MODELLER for Protein Structure Prediction
Rosignoli, Serena; Lustrino, Elisa; Di Silverio, Iris; Paiardini, Alessandro - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-20 - issn: 1422-0067 - wos: WOS:001160493200001 (1) - scopus: 2-s2.0-85184717314 (1)

11573/1720302 - 2024 - An outlook on structural biology after AlphaFold: tools, limits and perspectives
Rosignoli, Serena; Pacelli, Maddalena; Manganiello, Francesca; Paiardini, Alessandro - 01g Articolo di rassegna (Review)
paper: FEBS OPEN BIO (Hoboken NJ: Wiley & Sons Amsterdam : Elsevier) pp. 1-21 - issn: 2211-5463 - wos: WOS:001318796000001 (0) - scopus: 2-s2.0-85204642946 (0)

11573/1725671 - 2024 - Design and synthesis of novel compounds targeting both AURKA and HDAC enzymes.
Ruggieri, G.; Madia, V. N.; Patacchini, E.; Ialongo, D.; Albano, A.; Messore, A.; Saccoliti, F; Arpacioglu, M.; De Leo, A.; Scipione, L.; Rotili, D.; Fiorentino, F.; Paiardini, A.; Di Santo, R.; Costi, R. - 04f Poster
conference: EFMC-ISMC 2024 XXVIII EFMC International Symposium on Medicinal Chemistry (Rome, Italy)
book: EFMC-ISMC 2024 XXVIII EFMC International Symposium on Medicinal Chemistry - ()

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
paper: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 2682-2697 - issn: 1097-2765 - wos: WOS:001281962900001 (0) - scopus: 2-s2.0-85198588581 (0)

11573/1729153 - 2024 - Off-target inhibition of human dihydroorotate dehydrogenase (hDHODH) highlights challenges in the development of fat mass and obesity-associated protein (FTO) inhibitors
Tarullo, M.; Fernandez Rodriguez, G.; Iaiza, A.; Venezia, S.; Macone, A.; Incocciati, A.; Masciarelli, S.; Marchioni, M.; Giorgis, M.; Lolli, M. L.; Fornaseri, F.; Proietti, L.; Grebien, F.; Rosignoli, S.; Paiardini, A.; Rotili, D.; Mai, A.; Bochenkova, E.; Caflisch, A.; Fazi, F.; Fatica, A. - 01a Articolo in rivista
paper: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. - - issn: 2575-9108 - wos: WOS:001366197700001 (0) - scopus: 2-s2.0-85210408199 (0)

11573/1670827 - 2023 - Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1
Abdelbaki, Ahmed; Ascanelli, Camilla; Okoye, Cynthia N; Akman, H Begum; Janson, Giacomo; Min, Mingwei; Marcozzi, Chiara; Hagting, Anja; Grant, Rhys; De Luca, Maria; Asteriti, Italia Anna; Guarguaglini, Giulia; Paiardini, Alessandro; Lindon, Catherine - 01a Articolo in rivista
paper: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:000892556700005 (2) - scopus: 2-s2.0-85143112003 (2)

11573/1670054 - 2023 - AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation
Anna Asteriti, Italia; Polverino, Federica; Stagni, Venturina; Sterbini, Valentina; Ascanelli, Camilla; Davide Naso, Francesco; Mastrangelo, Anna; Rosa, Alessandro; Paiardini, Alessandro; Lindon, Catherine; Guarguaglini, Giulia - 01a Articolo in rivista
paper: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:000935019100001 (6) - scopus: 2-s2.0-85148256341 (6)

11573/1681779 - 2023 - When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases
Boi, Dalila; Rubini, Elisabetta; Breccia, Sara; Guarguaglini, Giulia; Paiardini, Alessandro - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000947160200001 (5) - scopus: 2-s2.0-85149819415 (5)

11573/1679516 - 2023 - Centaurea triumfetii essential oil chemical composition, comparative analysis, and antimicrobial activity of selected compounds
Carev, I; Gelemanović, A; Glumac, M; Tutek, K; Dželalija, M; Paiardini, A; Prosseda, G - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 7475- - issn: 2045-2322 - wos: WOS:001001538500012 (12) - scopus: 2-s2.0-85158121457 (13)

11573/1691212 - 2023 - A deep neural network for G-quadruplexes binding proteins classification
Di Luzio, F.; Paiardini, A.; Colonnese, F.; Rosato, A.; Panella, M. - 04b Atto di convegno in volume
conference: 17th International Work-Conference on Artificial Neural Networks, IWANN 2023 (Ponta Delgada; Portugal)
book: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) - (978-3-031-43084-8; 978-3-031-43085-5)

11573/1667930 - 2023 - A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression
Di Nisio, Elena; Licursi, Valerio; Mannironi, Cecilia; Buglioni, Valentina; Paiardini, Alessandro; Robusti, Giulia; Noberini, Roberta; Bonaldi, Tiziana; Negri, Rodolfo - 01a Articolo in rivista
paper: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 0929-1903 - wos: WOS:000918402800001 (5) - scopus: 2-s2.0-85146853977 (5)

11573/1681512 - 2023 - First-in-class selective inhibitors of the lysine acetyltransferase KAT8
Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, Francesca Romana; Iuzzolino, Angela; D'acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6591-6616 - issn: 1520-4804 - wos: WOS:000988858800001 (5) - scopus: 2-s2.0-85159627845 (5)

11573/1681026 - 2023 - Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells
Kunkl, Martina; Amormino, Carola; Spallotta, Francesco; Caristi, Silvana; Fiorillo, Maria Teresa; Paiardini, Alessandro; Kaempfer, Raymond; Tuosto, Loretta - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000988435800001 (4) - scopus: 2-s2.0-85159695596 (3)

11573/1706561 - 2023 - Protein structure prediction in drug discovery
Paiardini, Alessandro - 01a Articolo in rivista
paper: BIOMOLECULES (Basel: MDPI) pp. - - issn: 2218-273X - wos: WOS:001057594500001 (1) - scopus: 2-s2.0-85168740259 (1)

11573/1691811 - 2023 - PyPCN: protein contact networks in PyMOL
Rosignoli, Serena; Di Paola, Luisa; Paiardini, Alessandro - 01a Articolo in rivista
paper: BIOINFORMATICS ([Oxford] : Oxford University Press) pp. 1-3 - issn: 1367-4811 - wos: WOS:001101066800001 (2) - scopus: 2-s2.0-85176804397 (1)

11573/1689849 - 2023 - Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
paper: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (4) - scopus: 2-s2.0-85173505521 (4)

11573/1689850 - 2023 - Exploring innovative approaches to isolate a one-component c-di-GMP transducer: A pilot study
Scribani Rossi, C; Parisi, G; Paiardini, A; Rinaldo, S - 02a Capitolo o Articolo
book: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY - ()

11573/1689461 - 2023 - The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine
Scribani-Rossi, Chiara; Antonia Molina-Henares, María; Angeli, Simone; Cutruzzola, Francesca; Paiardini, Alessandro; Espinosa-Urgel, Manuel; Rinaldo, Serena - 01a Articolo in rivista
paper: FEMS MICROBIOLOGY LETTERS ([S.l.] : Blackwell S.l.] : Elsevier Science) pp. 1-9 - issn: 1574-6968 - wos: WOS:001046826600003 (1) - scopus: 2-s2.0-85168750549 (2)

11573/1687358 - 2023 - Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri
Trirocco, R.; Pasqua, M.; Tramonti, A.; Colonna, B.; Paiardini, A.; Prosseda, G. - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:001049367300071 (4) - scopus: 2-s2.0-85168194551 (4)

11573/1679518 - 2023 - Fatty Acids Abolish Shigella Virulence by Inhibiting Its Master Regulator, VirF
Trirocco, Rita; Pasqua, Martina; Tramonti, Angela; Grossi, Milena; Colonna, Bianca; Paiardini, Alessandro; Prosseda, Gianni - 01a Articolo in rivista
paper: MICROBIOLOGY SPECTRUM (Washington, DC : ASM Press, 2014-) pp. - - issn: 2165-0497 - wos: WOS:000981167800001 (2) - scopus: 2-s2.0-85163914189 (3)

11573/1652973 - 2022 - SARS-CoV-2 spike does not possess intrinsic superantigen-like inflammatory activity
Amormino, Carola; Tedeschi, Valentina; Paldino, Giorgia; Arcieri, Stefano; Fiorillo, Maria Teresa; Paiardini, Alessandro; Tuosto, Loretta; Kunkl, Martina - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000846047100001 (11) - scopus: 2-s2.0-85137600259 (12)

11573/1575071 - 2022 - A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins
Cutruzzolà, Francesca; Paiardini, Alessandro; Scribani Rossi, Chiara; Spizzichino, Sharon; Paone, Alessio; Giardina, Giorgio; Rinaldo, Serena - 01g Articolo di rassegna (Review)
paper: COORDINATION CHEMISTRY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214228- - issn: 0010-8545 - wos: WOS:000706196900003 (3) - scopus: 2-s2.0-85115933139 (3)

11573/1652497 - 2022 - A Novel Hypothesis on Choroideremia-Manifesting Female Carriers: Could CHM In-Frame Variants Exert a Dominant Negative Effect? A Case Report
Di Giosaffatte, Niccolò; Valiante, Michele; Tricarico, Stefano; Parise, Giulia; De Negri, Anna Maria; Ricciotti, Guido; Florean, Lara; Paiardini, Alessandro; Bottillo, Irene; Grammatico, Paola - 01a Articolo in rivista
paper: GENES (Basel : Molecular Diversity Preservation International) pp. 1-15 - issn: 2073-4425 - wos: WOS:000831455900001 (3) - scopus: 2-s2.0-85135136310 (4)

11573/1625113 - 2022 - Prediction and modeling of protein–protein interactions using “Spotted” peptides with a template-based approach
Gasbarri, C.; Rosignoli, S.; Janson, G.; Boi, D.; Paiardini, A. - 01a Articolo in rivista
paper: BIOMOLECULES (Basel: MDPI) pp. 201- - issn: 2218-273X - wos: WOS:000763712100001 (1) - scopus: 2-s2.0-85123311952 (3)

11573/1672677 - 2022 - A short ERAP2 that binds IRAP is expressed in macrophages independently of gene variation
Mattorre, Benedetta; Caristi, Silvana; Donato, Simona; Volpe, Emilia; Faiella, Marika; Paiardini, Alessandro; Sorrentino, Rosa; Paladini, Fabiana - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000794712100001 (4) - scopus: 2-s2.0-85129003386 (7)

11573/1670824 - 2022 - A machine learning perspective on DNA and RNA G-quadruplexes
Paiardini, Alessandro; Rossi, Fabiana - 01a Articolo in rivista
paper: CURRENT BIOINFORMATICS (Netherlands, BENTHAM SCIENCE PUBLISHERS) pp. - - issn: 1574-8936 - wos: WOS:000851376300001 (1) - scopus: 2-s2.0-85137335339 (1)

11573/1655650 - 2022 - DockingPie: a consensus docking plugin for PyMOL
Rosignoli, Serena; Paiardini, Alessandro - 01a Articolo in rivista
paper: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. 4233-4234 - issn: 1367-4803 - wos: WOS:000824423300001 (17) - scopus: 2-s2.0-85141892299 (15)

11573/1661534 - 2022 - Boosting the full potential of PyMOL with structural biology plugins
Rosignoli, Serena; Paiardini, Alessandro - 01g Articolo di rassegna (Review)
paper: BIOMOLECULES (Basel: MDPI) pp. 1764- - issn: 2218-273X - wos: WOS:000902276900001 (51) - scopus: 2-s2.0-85144708388 (64)

11573/1641216 - 2022 - Nutrient sensing and biofilm modulation: the example of L-arginine in Pseudomonas
Scribani Rossi, C; Barrientos-Moreno, L.; Paone, A.; Cutruzzola', F.; Paiardini, A.; Espinosa-Urgel, M.; Rinaldo, S. - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 4386- - issn: 1661-6596 - wos: WOS:000785501700001 (27) - scopus: 2-s2.0-85128190924 (29)

11573/1584599 - 2022 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 1625-1649 - issn: 1742-464X - wos: WOS:000717476400001 (4) - scopus: 2-s2.0-85118844105 (5)

11573/1615167 - 2021 - Pha-680626 is an effective inhibitor of the interaction between aurora-a and n-myc
Boi, D.; Souvalidou, F.; Capelli, D.; Polverino, F.; Marini, G.; Montanari, R.; Pochetti, G.; Tramonti, A.; Contestabile, R.; Trisciuoglio, D.; Carpinelli, P.; Ascanelli, C.; Lindon, C.; De Leo, A.; Saviano, M.; Di Santo, R.; Costi, R.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 13122- - issn: 1661-6596 - wos: WOS:000735123900001 (10) - scopus: 2-s2.0-85120777012 (10)

11573/1548792 - 2021 - Bacterial oxidases of the cytochrome bd family: redox enzymes of unique structure, function, and utility as drug targets
Borisov, V. B.; Siletsky, S. A.; Paiardini, A.; Hoogewijs, D.; Forte, E.; Giuffre, A.; Poole, R. K. - 01g Articolo di rassegna (Review)
paper: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1280-1318 - issn: 1523-0864 - wos: WOS:000590857300001 (58) - scopus: 2-s2.0-85105655418 (57)

11573/1534289 - 2021 - The archaeal elongation factor EF-2 induces the release of aIF6 from 50S ribosomal subunit
Lo Gullo, Giada; De Santis, Maria Luisa; Paiardini, Alessandro; Rosignoli, Serena; Romagnoli, Alice; La Teana, Anna; Londei, Paola; Benelli, Dario - 01a Articolo in rivista
paper: FRONTIERS IN MICROBIOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 631297- - issn: 1664-302X - wos: WOS:000637212200001 (3) - scopus: 2-s2.0-85103823367 (3)

11573/1492549 - 2021 - Studying ggdef domain in the act: Minimize conformational frustration to prevent artefacts
Mantoni, F.; Scribani Rossi, C.; Paiardini, A.; Di Matteo, A.; Cappellacci, L.; Petrelli, R.; Ricciutelli, M.; Paone, A.; Cutruzzola', F.; Giardina, G.; Rinaldo, S. - 01a Articolo in rivista
paper: LIFE (Basel: MDPI) pp. 1-13 - issn: 2075-1729 - wos: WOS:000610391100001 (4) - scopus: 2-s2.0-85100221529 (5)

11573/1573946 - 2021 - Phosphorylation, mg‐adp, and inhibitors differentially shape the conformational dynamics of the a‐loop of aurora‐a
Musavizadeh, Z.; Grottesi, A.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
paper: BIOMOLECULES (Basel: MDPI) pp. 567- - issn: 2218-273X - wos: WOS:000642785000001 (3) - scopus: 2-s2.0-85103937885 (3)

11573/1574100 - 2021 - Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer
Naso, F. D.; Boi, D.; Ascanelli, C.; Pamfil, G.; Lindon, C.; Paiardini, A.; Guarguaglini, G. - 01g Articolo di rassegna (Review)
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3917-3928 - issn: 0950-9232 - wos: WOS:000650165600001 (30) - scopus: 2-s2.0-85105789689 (27)

11573/1600685 - 2021 - Design and development of a versatile graphical user interface for assisting consensus docking analyses on therapeutic targets for cancer treatment.
Rosignoli, Serena; Paiardini, Alessandro - 04f Poster
conference: EMBO Workshop - Systems approaches in cancer (Split; Croatia)
book: Systems approaches in cancer - ()

11573/1558512 - 2021 - L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation
Scribani Rossi, Chiara; Mantoni, Federico; Giardina, Giorgio; Paiardini, Alessandro; Di Matteo, Adele; Cutruzzola', Francesca; Rinaldo, Serena - 04d Abstract in atti di convegno
conference: efb 2021 (online)
book: efb 2021 - ()

11573/1558505 - 2021 - Signal transduction and c-di-GMP second messenger: novel tools to investigare the mechanism of nutrient sensing.
Scribani Rossi, Chiara; Parisi, Giacomo; Giardina, Giorgio; Cutruzzola', Francesca; Paiardini, Alessandro; Rinaldo, Serena - 04d Abstract in atti di convegno
conference: WEBPRO - Proteins on the Web 2021. (online)
book: WEBPRO - Proteins on the Web 2021. - ()

11573/1553985 - 2021 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Tramonti, Angela; Paiardini, Alessandro; Contestabile, Roberto; Pochetti, Giorgio; Rinaldo, Serena; Paone, Alessio; Giardina, Giorgio; Cutruzzola', Francesca - 04d Abstract in atti di convegno
conference: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research (online)
book: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research Abstracts - ()

11573/1396096 - 2020 - Artemisinin derivatives with antimelanoma activity show inhibitory effect against human dna topoisomerase 1
Botta, Lorenzo; Filippi, Silvia; Zippilli, Claudio; Cesarini, Silvia; Bizzarri, Bruno Mattia; Cirigliano, Angela; Rinaldi, Teresa; Paiardini, Alessandro; Fiorucci, Diego; Saladino, Raffaele; Negri, Rodolfo; Benedetti, Pietro - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 1035-1040 - issn: 1948-5875 - wos: WOS:000535281200064 (19) - scopus: 2-s2.0-85087985664 (19)

11573/1656619 - 2020 - A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome
Bottillo, Irene; Valiante, Michele; Menale, Lucia; Paiardini, Alessandro; Papi, Laura; Janson, Giacomo; Sestini, Roberta; Iorio, Alessandra; De Simone, Paola; Frascione, Pasquale; Grammatico, Paola - 01a Articolo in rivista
paper: DERMATOLOGY ONLINE JOURNAL (University of California:25 Lower Freeborn:Davis, CA 95616:(916)752-0365, (916)752-0208, Fax: (916)752-0355) pp. - - issn: 1087-2108 - wos: (0) - scopus: 2-s2.0-85091193097 (2)

11573/1463758 - 2020 - Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000595956300001 (11) - scopus: 2-s2.0-85096677891 (12)

11573/1473676 - 2020 - A single center retrospective review of patients from central italy tested for melanoma predisposition genes
De Simone, P; Bottillo, I; Valiante, M; Iorio, A; De Bernardo, C; Majore, S; D'angelantonio, D; Valentini, T; Sperduti, I; Piemonte, P; Eibenschutz, L; Ferrari, A; Carbone, A; Buccini, P; Paiardini, A; Silipo, V; Frascione, P; Grammatico, P - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-17 - issn: 1661-6596 - wos: WOS:000602971200001 (2) - scopus: 2-s2.0-85097557593 (2)

11573/1473622 - 2020 - Intronic determinants coordinate charme lncRNA nuclear activity through the interaction with MATR3 and PTBP1
Desideri, F.; Cipriano, A.; Petrezselyova, S.; Buonaiuto, G.; Santini, T.; Kasparek, P.; Prochazka, J.; Janson, G.; Paiardini, A.; Calicchio, A.; Colantoni, A.; Sedlacek, R.; Bozzoni, I.; Ballarino, M. - 01a Articolo in rivista
paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:000601399100024 (22) - scopus: 2-s2.0-85098200912 (23)

11573/1486557 - 2020 - PyMod 3: a complete suite for structural bioinformatics in PyMOL
Janson, Giacomo; Paiardini, Alessandro - 01a Articolo in rivista
paper: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. - - issn: 1367-4803 - wos: WOS:000693168900019 (76) - scopus: 2-s2.0-85108387165 (81)

11573/1416609 - 2020 - SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase
Martone, J.; Mariani, D.; Santini, T.; Setti, A.; Shamloo, S.; Colantoni, A.; Capparelli, F.; Paiardini, A.; Dimartino, D.; Morlando, M.; Bozzoni, I. - 01a Articolo in rivista
paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. e49942- - issn: 1469-221X - wos: WOS:000528590900001 (21) - scopus: 2-s2.0-85084118101 (21)

11573/1458055 - 2020 - Insights into pparγphosphorylation and its inhibition mechanism
Montanari, R.; Capelli, D.; Yamamoto, K.; Awaishima, H.; Nishikata, K.; Barendregt, A.; Heck, A. J. R.; Loiodice, F.; Altieri, F.; Paiardini, A.; Grottesi, A.; Pirone, L.; Pedone, E.; Peiretti, F.; Brunel, J. M.; Itoh, T.; Pochetti, G. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4811-4823 - issn: 0022-2623 - wos: WOS:000535279800026 (23) - scopus: 2-s2.0-85084694697 (23)

11573/1648069 - 2020 - Structure and function of HD-GYP phosphodiesterases
Rinaldo, S.; Paiardini, A.; Paone, A.; Cutruzzola', F.; Giardina, G. - 02a Capitolo o Articolo
book: Microbial Cyclic Di-Nucleotide Signaling - (978-3-030-33307-2; 978-3-030-33308-9)

11573/1389775 - 2020 - From PARP1 to TNKS2 inhibition: A structure-based approach
Tomassi, Stefano; Pfahler, Julian; Mautone, Nicola; Rovere, Annarita; Esposito, Chiara; Passeri, Daniela; Pellicciari, Roberto; Novellino, Ettore; Pannek, Martin; Steegborn, Clemens; Paiardini, Alessandro; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:000535281200039 (11) - scopus: 2-s2.0-85087107488 (9)

11573/1343897 - 2019 - Custom scoring Aurora-A with SMINA
Esposito, Chiara; Grottesi, Alessandro; Janson, Giacomo; Paiardini, Alessandro - 04f Poster
conference: New Frontiers in Structure-Based Drug Discovery (Firenze)
book: New Frontiers in Structure-Based Drug Discovery - ()

11573/1244108 - 2019 - The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism
Guiducci, Giulia; Paone, Alessio; Tramonti, Angela; Giardina, Giorgio; Rinaldo, Serena; Bouzidi, Amani; Magnifico, Maria C; Marani, Marina; Menendez, Javier A; Fatica, Alessandro; Macone, Alberto; Armaos, Alexandros; Tartaglia, Gian G; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzolà, Francesca - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 1-16 - issn: 0305-1048 - wos: WOS:000473754300036 (29) - scopus: 2-s2.0-85067847112 (29)

11573/1263074 - 2019 - N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia
Ianniello, Zaira; Paiardini, Alessandro; Fatica, Alessandro - 01a Articolo in rivista
paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. - - issn: 2234-943X - wos: WOS:000463924400001 (58) - scopus: 2-s2.0-85067465851 (58)

11573/1625118 - 2019 - Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling
Janson, G.; Grottesi, A.; Pietrosanto, M.; Ausiello, G.; Guarguaglini, G.; Paiardini, A. - 01a Articolo in rivista
paper: PLOS COMPUTATIONAL BIOLOGY (San Francisco, CA : Public Library of Science, [2005]-) pp. e1007219- - issn: 1553-734X - wos: WOS:000507310800032 (8) - scopus: 2-s2.0-85077404153 (11)

11573/1270703 - 2019 - A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies
Montioli, Riccardo; Battini, Roberta; Paiardini, Alessandro; Tolve, Manuela; Bertoldi, Mariarita; Carducci, Carla; Leuzzi, Vincenzo; Borri Voltattorni, Carla - 01a Articolo in rivista
paper: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. - - issn: 1096-7192 - wos: WOS:000473555500004 (18) - scopus: 2-s2.0-85065612038 (18)

11573/1273070 - 2019 - R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features
Montioli, Riccardo; Paiardini, Alessandro; Giardina, Giorgio; Zanzoni, Serena; Cutruzzola, Francesca; Cellini, Barbara; Borri Voltattorni, Carla - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000476663500011 (8) - scopus: 2-s2.0-85064506502 (9)

11573/1349570 - 2019 - Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation.
Traversa, A; Bernardo, S; Paiardini, A; Giovannetti, A; Marchionni, E; Genovesi, Ml; Guadagnolo, D; Torres, B; Paolacci, S; Bernardini, L; Mazza, T; Carella, M; Caputo, V; Pizzuti, A - 01a Articolo in rivista
paper: MOLECULAR GENETICS & GENOMIC MEDICINE ([Hoboken, NJ] : John Wiley & Sons, [2013]-) pp. - - issn: 2324-9269 - wos: WOS:000497878100001 (5) - scopus: 2-s2.0-85075459805 (5)

11573/1176633 - 2018 - A novel germline mutation in CDK4 codon 24 associated to familial melanoma
Bottillo, I; La Starza, Sonia Roberta; Radio, F C; Molica, C; Pedace, L; Pierini, T; De Bernardo, C; Stingeni, L; Bargiacchi, Sara; Paiardini, A; Janson, G; Mecucci, C; Grammatico, P - 01f Lettera, Nota
paper: CLINICAL GENETICS (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 934-935 - issn: 0009-9163 - wos: WOS:000427471000027 (5) - scopus: 2-s2.0-85043995463 (5)

11573/1089335 - 2018 - Corrigendum to “Pyridoxine-5′-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g > A (P.·Arg116gln) mutation” [Mol. Genet. Metab. 122/1–2 (2017) 135–142]
Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01b Commento, Erratum, Replica e simili
paper: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 359-359 - issn: 1096-7192 - wos: WOS:000453637800007 (2) - scopus: 2-s2.0-85043513164 (2)

11573/1143149 - 2018 - The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells
Giardina, Giorgio; Paone, Alessio; Tramonti, Angela; Lucchi, Roberta; Marani, Marina; Magnifico, Maria Chiara; Bouzidi, Amani; Pontecorvi, Valentino; Guiducci, Giulia; Zamparelli, Carlotta; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3238-3253 - issn: 1742-464X - wos: WOS:000443814200008 (27) - scopus: 2-s2.0-85052452668 (29)

11573/1176648 - 2018 - Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: A case report
Lu, J; Zhao, X; Paiardini, A; Lang, Y; Bottillo, I; Shao, L - 01a Articolo in rivista
paper: BMC NEPHROLOGY (London: BioMed Central, 2000-) pp. 181- - issn: 1471-2369 - wos: WOS:000438997000005 (3) - scopus: 2-s2.0-85049898689 (4)

11573/1139413 - 2018 - Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa
Mantoni, Federico; Paiardini, Alessandro; Brunotti, Paolo; D'angelo, Cecilia; Cervoni, Laura; Paone, Alessio; Cappellacci, Loredana; Petrelli, Riccardo; Ricciutelli, Massimo; Leoni, Livia; Rampioni, Giordano; Arcovito, Alessandro; Rinaldo, Serena; Cutruzzolà, Francesca; Giardina, Giorgio - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3815-3834 - issn: 1742-464X - wos: WOS:000447880900011 (23) - scopus: 2-s2.0-85052825956 (26)

11573/1176644 - 2018 - Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii
Maresi, E; Janson, G; Fruncillo, S; Paiardini, A; Vallone, Roberto; Dominici, P; Astegno, A. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 2111- - issn: 1661-6596 - wos: WOS:000442807400290 (10) - scopus: 2-s2.0-85050592702 (10)

11573/1115382 - 2018 - Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations
Montioli, Riccardo; Janson, Giacomo; Paiardini, Alessandro; Bertoldi, Mariarita; Borri Voltattorni, Carla - 01a Articolo in rivista
paper: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 215-223 - issn: 1521-6543 - wos: WOS:000426066800005 (9) - scopus: 2-s2.0-85042453702 (9)

11573/1151881 - 2018 - A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa
Paiardini, A.; Mantoni, F.; Giardina, G.; Paone, A.; Janson, G.; Leoni, L.; Rampioni, G.; Cutruzzolà, F.; Rinaldo, S. - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0887-3585 - wos: WOS:000450353600008 (26) - scopus: 2-s2.0-85052809619 (28)

11573/1176640 - 2018 - Cysteine 180 is a redox sensor modulating activity of human pyridoxal 5'-phosphate histidine decarboxylase
Rossignoli, G; Grottesi, A; Bisello, G; Montioli, R; Borri Voltattorni, C; Paiardini, A; Bertoldi, M. - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. - - issn: 0006-2960 - wos: WOS:000449722300009 (4) - scopus: 2-s2.0-85056239838 (4)

11573/1131469 - 2018 - Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes
Tramonti, Angela; Paiardini, Alessandro; Paone, Alessio; Bouzidi, Amani; Giardina, Giorgio; Guiducci, Giulia; Magnifico, Maria Chiara; Rinaldo, Serena; Mcdermott, Lee; Menendez, Javier A.; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
paper: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 71-79 - issn: 0003-9861 - wos: WOS:000442192500007 (14) - scopus: 2-s2.0-85049429016 (13)

11573/952945 - 2017 - Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii
Astegno, Alessandra; Maresi, Elena; Bertoldi, Mariarita; La Verde, Valentina; Paiardini, Alessandro; Dominici, Paola - 01a Articolo in rivista
paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 939-955 - issn: 0264-6021 - wos: WOS:000395819600006 (19) - scopus: 2-s2.0-85016139429 (19)

11573/952949 - 2017 - Identification of small molecule inhibitors of the aurora-A/TPX2 complex
Asteriti, Italia Anna; Daidone, F; Colotti, G; Rinaldo, Serena; Lavia, P; Guarguaglini, Giulia; Paiardini, Alessandro - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. - - issn: 1949-2553 - wos: WOS:000401003200118 (21) - scopus: 2-s2.0-85019153604 (22)

11573/1015066 - 2017 - Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis
Brusotti, Gloria; Montanari, Roberta; Capelli, Davide; Cattaneo, Giulia; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Peiretti, Franck; Bonardo, Bernadette; Paiardini, Alessandro; Calleri, Enrica; Pochetti, Giorgio - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 5777- - issn: 2045-2322 - wos: WOS:000405746500088 (58) - scopus: 2-s2.0-85024485998 (63)

11573/954375 - 2017 - Glucose metabolism in the progression of prostate cancer
Cutruzzola', Francesca; Giardina, Giorgio; Marani, Marina; Macone, Alberto; Paiardini, Alessandro; Rinaldo, Serena; Paone, Alessio - 01a Articolo in rivista
paper: FRONTIERS IN PHYSIOLOGY (Lausanne: Frontiers Research Foundation, 2010-) pp. 97- - issn: 1664-042X - wos: WOS:000394487500001 (97) - scopus: 2-s2.0-85014162527 (105)

11573/1023679 - 2017 - Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ
Di Matteo, A; Franceschini, M; Paiardini, A; Grottesi, A; Chiarella, S; Rocchio, S; Di Natale, C; Marasco, D; Vitagliano, L; Travaglini-Allocatelli, C; Federici, L. - 01a Articolo in rivista
paper: ONCOGENESIS (London Nature Publishing Group) pp. e379- - issn: 2157-9024 - wos: WOS:000415010100004 (14) - scopus: 2-s2.0-85032725431 (15)

11573/1014987 - 2017 - Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO)
Di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01a Articolo in rivista
paper: DATA IN BRIEF (New York : Elsevier Inc.) pp. 868-875 - issn: 2352-3409 - wos: WOS:000453415100125 (12) - scopus: 2-s2.0-85032823566 (12)

11573/1001903 - 2017 - Pyridoxine-5'-phosphate oxidase (pnpo) deficiency. clinical and biochemical alterations associated with the c.347g>a (pp. arg116gln) mutation
Di Salvo, Martino Luigi; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo - 01a Articolo in rivista
paper: MOLECULAR GENETICS AND METABOLISM (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 1-8 - issn: 1096-7192 - wos: WOS:000413134800019 (28) - scopus: 2-s2.0-85030540261 (29)

11573/1010852 - 2017 - Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis
Giardina, Giorgio; Paiardini, Alessandro; Montioli, Riccardo; Cellini, Barbara; Voltattorni, Carla Borri; Cutruzzola', Francesca - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11704- - issn: 2045-2322 - wos: WOS:000410859400036 (14) - scopus: 2-s2.0-85029469719 (14)

11573/932336 - 2017 - PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL
Janson, Giacomo; Zhang, Chengxin; Prado, Maria Giulia; Paiardini, Alessandro - 01a Articolo in rivista
paper: BIOINFORMATICS (-Oxford : Oxford University Press, 1998-) pp. 444-446- - issn: 1367-4803 - wos: WOS:000397260800021 (111) - scopus: 2-s2.0-85019233554 (117)

11573/952944 - 2017 - New insights emerging from recent investigations on Human Group II pyridoxal 5'-phosphate decarboxylases
Paiardini, Alessandro; Giardina, Giorgio; Rossignoli, Giada; Voltattorni, Carla Borri; Bertoldi, Mariarita - 01a Articolo in rivista
paper: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 226-244 - issn: 0929-8673 - wos: WOS:000396017300001 (13) - scopus: 2-s2.0-85013635549 (12)

11573/1020398 - 2017 - Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases
Rinaldo, S.; Giardina, G.; Mantoni, F.; Paiardini, A.; Paone, Alessio; Cutruzzolã , Francesca - 02a Capitolo o Articolo
book: c-di-GMP signaling - (978-1-4939-7239-5; 978-1-4939-7240-1)

11573/931868 - 2016 - Prediction and visualization data for the interpretation of sarcomeric and non-sarcomeric DNA variants found in patients with hypertrophic cardiomyopathy
Bottillo, Irene; D'angelantonio, Daniela; Caputo, Viviana; Paiardini, Alessandro; Lipari, Martina; De Bernardo, Carmelilia; Majore, Silvia; Castori, Marco; Zachara, Elisabetta; Re, Federica; Grammatico, Paola - 01a Articolo in rivista
paper: DATA IN BRIEF (New York : Elsevier Inc.) pp. 607-613 - issn: 2352-3409 - wos: WOS:000453166200095 (0) - scopus: 2-s2.0-84962574347 (0)

11573/952939 - 2016 - Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions
Drinkwater, Nyssa; Vinh, Natalie B.; Mistry, Shailesh N.; Bamert, Rebecca S.; Ruggeri, Chiara; Holleran, John P.; Loganathan, Sasdekumar; Paiardini, Alessandro; Charman, Susan A.; Powell, Andrew K.; Avery, Vicky M.; Mcgowan, Sheena; Scammells, Peter J. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 43-64 - issn: 0223-5234 - wos: WOS:000371650900004 (42) - scopus: 2-s2.0-84955290142 (41)

11573/832010 - 2016 - In silico discovery and in vitro validation of catechol-containing sulfonohydrazide compounds as potent inhibitors of the diguanylate cyclase PleD
Fernicola, Silvia; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Leoni, Livia; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
paper: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 147-156 - issn: 0021-9193 - wos: WOS:000366587800006 (30) - scopus: 2-s2.0-84953898134 (41)

11573/845279 - 2016 - A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells
Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4570-4583 - issn: 1949-2553 - wos: WOS:000369952400069 (44) - scopus: 2-s2.0-84958012663 (44)

11573/1023676 - 2016 - The novel R347G pathogenic mutation of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency
Montioli, Riccardo; Paiardini, Alessandro; Kurian, Manju A.; Dindo, Mirco; Rossignoli, Giada; Heales, Simon J. R.; Pope, Simon; Voltattorni, Carla Borri; Bertoldi, Mariarita - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 676-682 - issn: 1570-9639 - wos: WOS:000374806200004 (17) - scopus: 2-s2.0-84962074484 (16)

11573/894263 - 2016 - Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming
Paiardini, Alessandro; Tramonti, Angela; Schirch, Doug; Guiducci, Giulia; Di Salvo, Martino Luigi; Fiascarelli, Alessio; Giorgi, Alessandra; Maras, Bruno; Cutruzzola', Francesca; Contestabile, Roberto - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1506-1517 - issn: 1570-9639 - wos: WOS:000383935100005 (37) - scopus: 2-s2.0-84982202451 (36)

11573/982304 - 2016 - Genotype-phenotype correlation study through protein model of 3- methylcrotonyl-CoA carboxylase
Tolve, Manuela; Paiardini, Alessandro; Janson, Giacomo; Artiola, Cristiana; Scarno, G; Giovanniello, Teresa; Pasquali, Amelia; Angeloni, Antonio; Carducci, Claudia; Leuzzi, Vincenzo; Carducci, Carla - 04c Atto di convegno in rivista
paper: JOURNAL OF INHERITED METABOLIC DISEASE (Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 79-79 - issn: 0141-8955 - wos: (0) - scopus: (0)

11573/845848 - 2015 - Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy.
Bottillo, Irene; D'angelantonio, Daniela; Caputo, Viviana; Paiardini, Alessandro; Lipari, Martina; De Bernardo, C; Giannarelli, D; Pizzuti, Antonio; Majore, S; Castori, M; Zachara, E; Re, F; Grammatico, Paola - 01a Articolo in rivista
paper: GENE (Amsterdam Netherlands: Elsevier BV) pp. 227-235 - issn: 0378-1119 - wos: WOS:000369191500017 (27) - scopus: 2-s2.0-84952864713 (31)

11573/808531 - 2015 - X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17
Drinkwater, Nyssa; Bamert, Rebecca S.; Sivaraman, Komagal Kannan; Paiardini, Alessandro; Mcgowan, Sheena - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 789-795 - issn: 0887-3585 - wos: WOS:000351520400018 (12) - scopus: 2-s2.0-84925332596 (12)

11573/832011 - 2015 - Synthesis of triazole-linked analogues of c-di-gmp and their interactions with diguanylate cyclase
Fernicola, Silvia; Torquati, Ilaria; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Messina, Marco; Leoni, Livia; Del Bello, Fabio; Petrelli, Riccardo; Rinaldo, Serena; Cappellacci, Loredana; Cutruzzola', Francesca - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8269-8284 - issn: 0022-2623 - wos: WOS:000363915600025 (30) - scopus: 2-s2.0-84945345287 (35)

11573/780499 - 2015 - How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; Di Salvo, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000352226400005 (74) - scopus: 2-s2.0-84964265516 (79)

11573/808565 - 2015 - Screening the medicines for malaria venture "malaria box" against the Pasmodium falciparum aminopeptidases, m1, m17 and m18
Paiardini, Alessandro; Bamert, Rebecca S.; Kannan Sivaraman, Komagal; Drinkwater, Nyssa; Mistry, Shailesh N.; Scammells, Peter J.; Mcgowan, Sheena - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0115859- - issn: 1932-6203 - wos: WOS:000349789800004 (34) - scopus: 2-s2.0-84923667053 (36)

11573/780502 - 2015 - Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase
Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 490-497 - issn: 1860-7179 - wos: WOS:000350456200006 (28) - scopus: 2-s2.0-84923349870 (29)

11573/781589 - 2015 - Structural basis of functional diversification of the HD-GYP domain revealed by the pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site
Rinaldo, Serena; Paiardini, Alessandro; Stelitano, Valentina; Brunotti, Paolo; Cervoni, Laura; Fernicola, Silvia; Protano, Carmela; Vitali, Matteo; Cutruzzola', Francesca; Giardina, Giorgio - 01a Articolo in rivista
paper: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1525-1535 - issn: 0021-9193 - wos: WOS:000351738600021 (28) - scopus: 2-s2.0-84930786571 (30)

11573/808580 - 2015 - Identification and validation of a potent dual Inhibitor of the P. falciparum M1 and M17 aminopeptidases using virtual screening
Ruggeri, Chiara; Drinkwater, Nyssa; Sivaraman, Komagal Kannan; Bamert, Rebecca S; Mcgowan, Sheena; Paiardini, Alessandro - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0138957- - issn: 1932-6203 - wos: WOS:000361800700129 (19) - scopus: 2-s2.0-84947227435 (19)

11573/557449 - 2014 - On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase
Di Salvo, Martino Luigi; Remesh, Sg; Vivoli, Mirella; Ghatge, Ms; Paiardini, Alessandro; D'aguanno, S; Safo, Mk; Contestabile, Roberto - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 129-145 - issn: 1742-464X - wos: WOS:000330591100011 (62) - scopus: 2-s2.0-84891832957 (62)

11573/556744 - 2014 - Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis
Itamar, Kass; David E., Hoke; M. G. S., Costa; Cyril F., Reboul; B. T., Porebski; N. P., Cowieson; Herve, Leh; Pennacchietti, Eugenia; J., Mccoey; Oded, Kleifeld; Carla Borri, Voltattorni; David, Langley; Brendan, Roome; Ian R., Mackay; Daniel, Christ; David, Perahia; M., Buckle; Paiardini, Alessandro; De Biase, Daniela; A. M., Buckle - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. E2524-E2529 - issn: 0027-8424 - wos: WOS:000337760600005 (33) - scopus: 2-s2.0-84903461226 (34)

11573/739204 - 2014 - Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors.
Mistry, Sn; Drinkwater, N; Ruggeri, Chiara; Sivaraman, Kk; Loganathan, S; Fletcher, S; Drag, M; Paiardini, Alessandro; Avery, Vm; Scammells, Pj; Mcgowan, S. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. - - issn: 0022-2623 - wos: WOS:000344977400035 (46) - scopus: 2-s2.0-84923775047 (47)

11573/1681788 - 2014 - PLP-dependent enzymes
Paiardini, A.; Contestabile, R.; Buckle, A. M.; Cellini, B. - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. - - issn: 2314-6133 - wos: WOS:000330527900001 (11) - scopus: 2-s2.0-84893776886 (11)

11573/557925 - 2014 - PLP-dependent enzymes.
Paiardini, Alessandro; Contestabile, Roberto; Buckle, Am; Cellini, B. - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL (London: Hindawi, [2001]-) pp. Article ID 856076-Article ID 856076 - issn: 2314-6141 - wos: WOS:000330527900001 (11) - scopus: 2-s2.0-84893776886 (11)

11573/542045 - 2014 - The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.
Paiardini, Alessandro; P., Aducci; Cervoni, Laura; Cutruzzola', Francesca; C. D., Lucente; Janson, Giacomo; Pascarella, Stefano; Rinaldo, Serena; S., Visconti; L., Camoni - 01a Articolo in rivista
paper: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 52-62 - issn: 1521-6543 - wos: WOS:000331299000008 (24) - scopus: 2-s2.0-84893774983 (24)

11573/618583 - 2014 - SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. e1525- - issn: 2041-4889 - wos: WOS:000345643900019 (90) - scopus: 2-s2.0-84923383679 (91)

11573/514722 - 2013 - The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
Davide, Antoniani; Elio, Rossi; Rinaldo, Serena; Paola, Bocci; Marco, Lolicato; Paiardini, Alessandro; Nadia, Raffaelli; Cutruzzola', Francesca; Paolo, Landini - 01a Articolo in rivista
paper: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (Germany: Springer Verlag Germany:Tiergartenstrasse) pp. 7325-7336 - issn: 0175-7598 - wos: WOS:000322408100024 (63) - scopus: 2-s2.0-84881232457 (71)

11573/513451 - 2013 - Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection
Di Salvo, Martino Luigi; Contestabile, Roberto; Paiardini, Alessandro; Maras, Bruno - 01a Articolo in rivista
paper: MEDICAL HYPOTHESES (-CHURCHILL LIVINGSTONE, JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH, SCOTLAND, MIDLOTHIAN, EH1 3AF -Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 633-636 - issn: 0306-9877 - wos: WOS:000317995000028 (53) - scopus: 2-s2.0-84875616592 (53)

11573/501940 - 2013 - Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity
Di Salvo, Martino Luigi; Florio, Rita; Paiardini, Alessandro; Vivoli, Mirella; Simona, D'aguanno; Contestabile, Roberto - 01a Articolo in rivista
paper: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 55-65 - issn: 0003-9861 - wos: WOS:000314388900001 (33) - scopus: 2-s2.0-84871911425 (32)

11573/525771 - 2013 - Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications
E., Oppici; K., Fodor; Paiardini, Alessandro; C., Williams; C. B., Voltattorni; M., Wilmanns; B., Cellini - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1457-1465 - issn: 0887-3585 - wos: WOS:000329220400015 (22) - scopus: 2-s2.0-84880700894 (21)

11573/534127 - 2013 - Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: Clues from the structure of the catalytic domain
Giardina, Giorgio; Paiardini, Alessandro; Fernicola, Silvia; Stefano, Franceschini; Rinaldo, Serena; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e81324- - issn: 1932-6203 - wos: WOS:000327541700059 (36) - scopus: 2-s2.0-84896718101 (40)

11573/525772 - 2013 - Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum.
Kannan Sivaraman, K; Paiardini, Alessandro; Sieńczyk, M; Ruggeri, Chiara; Oellig, Ca; Dalton, Jp; Scammells, Pj; Drag, M; Mcgowan, S. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5213-5217 - issn: 0022-2623 - wos: WOS:000321237100032 (57) - scopus: 2-s2.0-84879558016 (56)

11573/528747 - 2013 - Type I pyridoxal 5'-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines.
Milano, Teresa; Paiardini, Alessandro; Grgurina, Ingeborg; Pascarella, Stefano - 01a Articolo in rivista
paper: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 1-31 - issn: 1472-6807 - wos: WOS:000329231800001 (17) - scopus: 2-s2.0-84885991881 (19)

11573/515471 - 2013 - Structural mimicry between SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: insights from an in silico study
Paiardini, Alessandro; Pascarella, Stefano - 01a Articolo in rivista
paper: THEORETICAL BIOLOGY AND MEDICAL MODELLING (London : BioMed Central, 2004-) pp. 25- - issn: 1742-4682 - wos: WOS:000318074400001 (12) - scopus: 2-s2.0-84875956630 (16)

11573/434272 - 2013 - Chemogenomics of pyridoxal 5'-phosphate dependent enzymes.
Singh, R; Spyrakis, F; Cozzini, P; Paiardini, Alessandro; Pascarella, Stefano; Mozzarelli, A. - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 183-194 - issn: 1475-6366 - wos: WOS:000313663400023 (12) - scopus: 2-s2.0-84874162455 (11)

11573/525774 - 2013 - C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG
Stelitano, Valentina; Giardina, Giorgio; Paiardini, Alessandro; Castiglione, Nicoletta; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e74920- - issn: 1932-6203 - wos: WOS:000324494000139 (46) - scopus: 2-s2.0-84884194723 (50)

11573/501033 - 2012 - Rapid profiling of disease alleles using a tunable reporter of protein misfolding
A. M. C., Pittman; M. D., Lage; V., Poltoratsky; J. D., Vrana; Paiardini, Alessandro; A., Roncador; B., Cellini; R. M., Hughes; C. L., Tucker - 01a Articolo in rivista
paper: GENETICS (Genetics Society of America:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7029, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728) pp. 831-842 - issn: 0016-6731 - wos: WOS:000310793900005 (17) - scopus: 2-s2.0-84869077214 (20)

11573/434078 - 2012 - Molecular insights into primary hyperoxaluria type i pathogenesis
Barbara, Cellini; E., Oppici; Paiardini, Alessandro; R., Montioli - 01a Articolo in rivista
paper: FRONTIERS IN BIOSCIENCE (Frontiers in Bioscience:PO Box 160:Albertson, NY 11507:(516)484-2831, (516)484-0813, EMAIL: fbsadmin@bioscience.org, INTERNET: http://www.bioscience.org, Fax: (516)484-2831) pp. 621-634 - issn: 1093-9946 - wos: WOS:000300049600015 (25) - scopus: 2-s2.0-84860351331 (29)

11573/446775 - 2012 - PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL
Bramucci, Emanuele; Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
paper: BMC BIOINFORMATICS ([London]: BioMed Central, [2000]-) pp. S2- - issn: 1471-2105 - wos: WOS:000303936400003 (144) - scopus: 2-s2.0-84864192056 (147)
conference: 8th Annual Meeting of the Italian-Society-of-Bioinformatics (BITS) (Pisa, ITALY)

11573/442251 - 2012 - Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors
Daidone, Frederick; Riccardo, Montioli; Paiardini, Alessandro; Barbara, Cellini; Antonio, Macchiarulo; Giardina, Giorgio; Bossa, Francesco; Carla Borri, Voltattorni - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e31610-e31610 - issn: 1932-6203 - wos: WOS:000302916100026 (54) - scopus: 2-s2.0-84857609756 (60)

11573/499750 - 2012 - Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine-Thr3 from Streptomyces sp OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR
Fullone, Maria Rosaria; Paiardini, Alessandro; Miele, Rossella; Marsango, Sara; Dennis C., Gross; Satoshi, Omura; Enric Ros, Herrera; Bonaccorsi Di Patti, Maria Carmela; Lagana', Aldo; Pascarella, Stefano; Grgurina, Ingeborg - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4269-4282 - issn: 1742-464X - wos: WOS:000311432900002 (14) - scopus: 2-s2.0-84870062977 (14)

11573/406527 - 2011 - PyMod: a tool for the analysis of protein structures and sequences in PyMOL
Bramucci, Emanuele; Paiardini, Alessandro; Pascarella, Stefano - 04d Abstract in atti di convegno
conference: BITS Annual meeting 2011 (Pisa)

11573/377566 - 2011 - In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Daidone, Frederick; Florio, Rita; Rinaldo, Serena; Contestabile, Roberto; Di Salvo, Martino Luigi; Cutruzzola', Francesca; Bossa, Francesco; Paiardini, Alessandro - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1616-1621 - issn: 0223-5234 - wos: WOS:000289655100017 (51) - scopus: 2-s2.0-79953228534 (53)

11573/389297 - 2011 - IDENTIFICATION BY VIRTUAL SCREENING AND IN VITRO TESTING OF NOVEL HUMAN DOPA DECARBOXYLASE INHIBITORS
F., Daidone; R., Montioli; Paiardini, Alessandro; B., Cellini; A., Macchiarulo; Giardina, Giorgio; Bossa, Francesco; C., Borri Voltattorni - 04d Abstract in atti di convegno
conference: FEBS Congress 2011 (Torino)

11573/409570 - 2011 - Molecular cloning of the biosynthetic cluster involved in the production of 4-chlorothreonine in Streptomyces sp. OH-5093: insight into the structure-activity relationship of a new nonheme Fe(II) halogenase
Fullone, Maria Rosaria; Miele, Rossella; Bonaccorsi Di Patti, Maria Carmela; E., Ros Herrera; L., Pirone; L., Cattaneo; Marsango, Sara; Paiardini, Alessandro; Grgurina, Ingeborg - 04a Atto di comunicazione a congresso
conference: Nature Aided Drug Discovery (NADD) (Napoli)

11573/410615 - 2011 - Crystal structure of the apo form of human aromatic L-amino acid decarboxylase: an open conformation unveils novel insights into the mechanism of PLP addition to the apoenzymes of group II decarboxylases
Giardina, Giorgio; Montioli, R.; Gianni, Stefano; Cellini, B.; Paiardini, Alessandro; Voltattorni, Cb; Cutruzzola', Francesca - 04d Abstract in atti di convegno
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 263-263 - issn: 1742-464X - wos: WOS:000292333102058 (0) - scopus: (0)
conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/426205 - 2011 - Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
Giardina, Giorgio; R., Montioli; Gianni, Stefano; B., Cellini; Paiardini, Alessandro; C., Borri Voltattorni; Cutruzzola', Francesca - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 20514-20519 - issn: 0027-8424 - wos: WOS:000298289400055 (88) - scopus: 2-s2.0-84855517335 (86)

11573/389117 - 2011 - IN SILICO AND IN VITRO VALIDATION OF SERINE HYDROXYMETHYLTRANSFERASE AS A CHEMOTHERAPEUTIC TARGET OF THE ANTIFOLATE DRUG PEMETREXED.
Paiardini, Alessandro - 04d Abstract in atti di convegno
conference: Febs Congress 2011 (Torino)

11573/224845 - 2011 - Bioinformatica: dalla sequenza alla struttura delle proteine
Pascarella, Stefano; Paiardini, Alessandro - 03a Saggio, Trattato Scientifico

11573/406542 - 2011 - Structural adaptation of enzymes from halophilic organisms
Siglioccolo, Alessandro; Paiardini, Alessandro; M., Piscitelli; Pascarella, Stefano - 04d Abstract in atti di convegno
conference: BITS annual meeting 2011 (Pisa)

11573/433699 - 2011 - Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface
Siglioccolo, Alessandro; Paiardini, Alessandro; Maria, Piscitelli; Pascarella, Stefano - 01a Articolo in rivista
paper: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 50- - issn: 1472-6807 - wos: WOS:000301202900001 (113) - scopus: 2-s2.0-84055213697 (125)

11573/389443 - 2010 - MOLECULAR DEFECTS OF THE GLYCINE 41 VARIANTS OF ALANINE:GLYOXYLATE AMINOTRANSFERASE ASSOCIATED WITH PRIMARY HYPEROXALURIA TYPE I
B., Cellini; R., Montioli; Paiardini, Alessandro; A., Lorenzetto; F., Maset; T., Bellini; E., Oppici; C., Borri Voltattorni - 04d Abstract in atti di convegno
conference: Congresso Proteine 2010 (Parma)

11573/131782 - 2010 - Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I.
Cellini, B; Montioli, R; Paiardini, Alessandro; Lorenzetto, A; Maset, F; Bellini, T; Oppici, E; Voltattorni, Cb - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 2896-2901 - issn: 0027-8424 - wos: WOS:000274599500036 (62) - scopus: 2-s2.0-77649267180 (61)

11573/389445 - 2010 - COMPUTER-AIDED DRUG DESIGN OF COMPETITIVE INHIBITORS OF L-DOPA-DECARBOXYLASE, A TARGET FOR THE TREATMENT OF PARKINSON'S DISEASE
F., Daidone; R., Montioli; Paiardini, Alessandro; A., Macchiarulo; Pascarella, Stefano; R., Pellicciari; C., Voltattorni; F., Bossa - 04d Abstract in atti di convegno
conference: Congresso Proteine 2010 (Parma)

11573/228709 - 2010 - Expression of Bv8 in pichia pastoris to identify structural features for receptor binding
Miele, Rossella; Lattanzi, Roberta; Bonaccorsi Di Patti, Maria Carmela; Paiardini, Alessandro; Negri, Lucia; Barra, Donatella - 01a Articolo in rivista
paper: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. 10-14 - issn: 1046-5928 - wos: WOS:000279312700002 (15) - scopus: 2-s2.0-77955428111 (15)

11573/389648 - 2010 - A CHEMOGENOMIC APPROACH TO THE DEVELOPMENT OF SPECIFIC LIGANDS FOR PLP-DEPENDENT ENZYMES
R., Singh; Paiardini, Alessandro; B., Campanini; F., Spyrakis; P., Cozzini; C., Giunta; A., Mozzarelli - 04d Abstract in atti di convegno
conference: Congresso Proteine 2010 (Parma)

11573/145268 - 2009 - Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation.
Cellini, B; Montioli, R; Paiardini, Alessandro; Lorenzetto, A; Borri Voltattorni, C. - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 8349-8358 - issn: 0021-9258 - wos: WOS:000264397800019 (51) - scopus: 2-s2.0-67649732393 (52)

11573/362128 - 2009 - Structural stability of the cofactor binding site in Escherichia coli serine hydroxymethyltransferase--the role of evolutionarily conserved hydrophobic contacts.
Florio, Rita; Chiaraluce, Roberta; Consalvi, Valerio; Paiardini, Alessandro; Catacchio, B; Bossa, Francesco; Contestabile, Roberto - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 7319-7328 - issn: 1742-464X - wos: WOS:000272172600011 (3) - scopus: 2-s2.0-71949091428 (3)

11573/362968 - 2009 - The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
Florio, Rita; Chiaraluce, Roberta; Consalvi, Valerio; Paiardini, Alessandro; Catacchio, B; Bossa, Francesco; Contestabile, Roberto - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 132-143 - issn: 1742-464X - wos: WOS:000261683900012 (13) - scopus: 2-s2.0-57649153157 (13)

11573/145270 - 2009 - An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme.
Montioli, R; Cellini, B; Bertoldi, M; Paiardini, Alessandro; Voltattorni, Cb - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 301-317 - issn: 0887-3585 - wos: WOS:000262100800003 (9) - scopus: 2-s2.0-59449102837 (8)

11573/230259 - 2009 - Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): Molecular modeling and surface analysis by computational methods and limited proteolysis
V., Severino; Paiardini, Alessandro; Pascarella, Stefano; A., Parente; A., Chambery - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (-Attuale :ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE -Butterworth Heinemann Publishers:Linacre House Jordan Hill, Oxford OX2 8DP United Kingdom:011 44 1865 314569, EMAIL: bhmarketing@repp.co.uk, INTERNET: http://www.laxtonsprices.co.uk, Fax: 011 44 1865 314569) pp. 407-413 - issn: 0141-8130 - wos: WOS:000271052400014 (3) - scopus: 2-s2.0-70149106350 (3)

11573/145267 - 2008 - Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: Spectroscopic and kinetic analysis
Bertoldi, M; Cellini, B; Paiardini, Alessandro; Montioli, R; Borri Voltattorni, C. - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1356-1362 - issn: 1570-9639 - wos: WOS:000259388800029 (4) - scopus: 2-s2.0-53149086699 (4)

11573/145265 - 2008 - Insights into the interaction of sortilin with proneurotrophins: A computational approach
Paiardini, Alessandro; Caputo, Viviana - 01a Articolo in rivista
paper: NEUROPEPTIDES (Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 205-214 - issn: 0143-4179 - wos: WOS:000254779400009 (17) - scopus: 2-s2.0-39849110118 (20)

11573/227624 - 2008 - "Hot cores" in proteins: Comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms
Paiardini, Alessandro; Riccardo, Sali; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
paper: BMC STRUCTURAL BIOLOGY (London: BioMed Central.) pp. 14-31 - issn: 1472-6807 - wos: WOS:000255177300002 (18) - scopus: 2-s2.0-42149186292 (18)

11573/145263 - 2007 - Human wild-type alanine : glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications
Barbara, Cellini; Mariarita, Bertoldi; Riccardo, Montioli; Paiardini, Alessandro; Carla, Borri Voltattorni - 01a Articolo in rivista
paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 39-50 - issn: 0264-6021 - wos: WOS:000250951800005 (89) - scopus: 2-s2.0-36349021899 (92)

11573/235513 - 2007 - Mutational analysis and homology modelling of SyrC, the aminoacyltransferase in the biosynthesis of syringomycin
Fullone, Maria Rosaria; Paiardini, Alessandro; Dennis C., Gross; Shi En, Lu; Alberto, Fiore; Grgurina, Ingeborg - 01a Articolo in rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 201-207 - issn: 0006-291X - wos: WOS:000251021100002 (3) - scopus: 2-s2.0-35448942727 (3)

11573/145262 - 2006 - Dimerization and folding processes of Treponema denticola cystalysin: the role of pyridoxal 5'-phosphate.
Cellini, B; Bertoldi, M; Montioli, R; Laurents D., V; Paiardini, Alessandro; Voltattorni, Cb - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 14140-14154 - issn: 0006-2960 - wos: WOS:000242179100022 (18) - scopus: 2-s2.0-33751560419 (20)

11573/389114 - 2006 - PLP-dependent enzymes: new answers to old questions
Paiardini, Alessandro - 04a Atto di comunicazione a congresso
conference: Proteins in Rome (Roma)

11573/1314736 - 2006 - "Hot cores": comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms
Paiardini, Alessandro; Sali, Riccardo; Pascarella, Stefano - 04d Abstract in atti di convegno
conference: Proteine 2006 (Novara)
book: Protyeine 2006: ATTI - ()

11573/145261 - 2006 - A 3D model of Reelin subrepeat regions predicts Reelin binding to carbohydrates
Roger, Panteri; Paiardini, Alessandro; Flavio, Keller - 01a Articolo in rivista
paper: BRAIN RESEARCH (Amsterdam; Lausanne; New York; Oxford; Shannon; Tokyo: Elsevier) pp. 222-230 - issn: 0006-8993 - wos: WOS:000241793900027 (10) - scopus: 2-s2.0-33749347872 (10)

11573/235852 - 2005 - CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
paper: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 50-55 - issn: 0305-1048 - wos: WOS:000230271400008 (22) - scopus: 2-s2.0-23144434732 (22)

11573/144415 - 2004 - Site-directed mutagenesis provides insight into racemization and transamination of alanine catalyzed by Treponema denticola cystalysin
B., Cellini; M., Bertoldi; Paiardini, Alessandro; S., D'aguanno; C. B., Voltattorni - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 36898-36905 - issn: 0021-9258 - wos: WOS:000223453600092 (11) - scopus: 2-s2.0-4344706396 (12)

11573/389112 - 2004 - ENZIMI PIRIDOSSAL-5’-DIPENDENTI: UN PARADIGMA DI VERSATILITA’ STRUTTURALE
Paiardini, Alessandro - 04a Atto di comunicazione a congresso
conference: Seminari Centro di Eccellenza di Biologia e Medicina Sperimentale (BEMM) (Roma)

11573/236607 - 2004 - Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5'-phosphate-dependent enzymes
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
paper: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 2992-3005 - issn: 0961-8368 - wos: WOS:000224762800016 (34) - scopus: 2-s2.0-7244238406 (33)

11573/389987 - 2004 - Structurally conserved regions and hydrophobic contacts in the fold type I, PLP-dependent enzymes
Paiardini, Alessandro; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
paper: ITALIAN JOURNAL OF BIOCHEMISTRY (Il Pensiero Scientifico) pp. 18-18 - issn: 0021-2938 - wos: (0) - scopus: (0)
conference: Proteine 2004 (Viterbo)

11573/254540 - 2003 - Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications
Mariarita, Bertoldi; Barbara, Cellini; Paiardini, Alessandro; Di Salvo, Martino Luigi; Carla Borri, Voltattorni - 01a Articolo in rivista
paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 473-483 - issn: 0264-6021 - wos: WOS:000182437200026 (18) - scopus: 2-s2.0-0038302704 (19)

11573/251097 - 2003 - Threonine aldolase and alanine racemase: novel examples of convergent evolution in the superfamily of vitamin B6-dependent enzymes
Paiardini, Alessandro; Contestabile, Roberto; D'aguanno, Simona; Pascarella, Stefano; Bossa, Francesco - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214-219 - issn: 0006-3002 - wos: WOS:000182549400037 (27) - scopus: 2-s2.0-0037974655 (32)

11573/406700 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferase
Paiardini, Alessandro; Gianese, G.; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
paper: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 105-105 - issn: 0961-8368 - wos: (0) - scopus: (0)
conference: Fifth European Symposium of the Protein Society (Firenze)

11573/1307047 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferases
Paiardini, Alessandro; Gianese, Giulio; Bossa, Francesco; Pascarella, Stefano - 04c Atto di convegno in rivista
paper: ITALIAN JOURNAL OF BIOCHEMISTRY (Il Pensiero Scientifico) pp. 55-55 - issn: 0021-2938 - wos: (0) - scopus: 2-s2.0-0041733553 (3)
conference: SIB-BIB 2003 (Milano)

11573/254004 - 2003 - Structural plasticity of thermophilic serine hydroxymethyltransferase
Paiardini, Alessandro; Gianese, Giulio; Bossa, Francesco; Pascarella, Stefano - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 122-134 - issn: 0887-3585 - wos: WOS:000180131100012 (26) - scopus: 2-s2.0-0037236096 (32)

11573/399901 - 2003 - A strategy for detection of structural conserved regions and contacts in protein superfamilies: application to the PLP-dependent enzymes
Paiardini, Alessandro; L., Di Vincenzo; Bossa, Francesco; Pascarella, Stefano - 04d Abstract in atti di convegno
conference: European Conference on Computational Biology (Parigi)
book: Proceeding of the European Conference on Computation Biology in conjunction with the French National Conference on Bioinformatics (JOBIM 2003) - ()

11573/410068 - 2002 - “L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functions”, in the 3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins, Southampton, United Kingdom, 14-19 April 2002.
Contestabile, Roberto; Paiardini, Alessandro; Pascarella, Stefano; Di Salvo, Martino Luigi; D'aguanno, S; Bossa, Francesco - 04a Atto di comunicazione a congresso
conference: 3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins (Southampton, United Kingdom)

11573/1306916 - 2001 - L-threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase: structural diversity and uniformity in a subgroup of closely related enzymes catalysing different reactions
Contestabile, R.; Paiardini, A.; Pascarella, S.; Bossa, F. - 04c Atto di convegno in rivista
paper: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 145-145 - issn: 0961-8368 - wos: (0) - scopus: (0)
conference: Fourth European Symposium of the Protein society (Parigi)

11573/410266 - 2001 - COMUNICAZIONE ORALE A CONGRESSO SU INVITO “Studies on the evolutionary origins of pyridoxal-phosphate-dependent enzymes: catalytic promiscuity and reaction specificity”, in “Quo Vadis Proteomics”, Napoli, 26 Marzo 2001.
Contestabile, Roberto; Paiardini, Alessandro; Bossa, Francesco - 04a Atto di comunicazione a congresso

11573/248895 - 2001 - L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subsgroup of strictly related enzymes specialized for different functions
Contestabile, Roberto; Paiardini, Alessandro; Pascarella, Stefano; Di Salvo, Martino Luigi; D'aguanno, Simona; Bossa, Francesco - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 6508-6525 - issn: 0014-2956 - wos: WOS:000172788400020 (79) - scopus: 2-s2.0-0035666383 (85)

11573/399998 - 2001 - Structural adaptation of serine hydroxymethyltransferase to extreme environments
Paiardini, Alessandro; Pascarella, Stefano; Bossa, Francesco - 04d Abstract in atti di convegno
conference: 4th International Conference on Molecular Structural Biology (Vienna)
book: Proceeding of the 4th International Conference on Molecular Structural Biology - (9783900554323)

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma