telefono: 06499109761
edificio: CU027
stanza: T9

Alessandro Giuffrè, Director
Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR-IBPM), P.le Aldo Moro 5, 00185, Rome, Italy

Author identifiers:
Orcid ID: 0000-0001-5301-0681
Scopus Author ID: 7003270357
WoS Researcher ID: K-4341-2015
Loop: 184580
Research Gate: Alessandro_Giuffre
Google Scholar: yuiCJh8AAAAJ

-1993: University Degree cum laude in Biology, Sapienza University of Rome.
-1997: PhD in Biochemistry, Sapienza University of Rome.

-Apr 2020 to date: Director of CNR-IBPM, Rome
-Feb 2020/Apr 2020: Science Manager at CNR-IBPM, Rome
-Jul 2001/Feb 2020: Senior Research Fellow at CNR-IBPM, Rome
-Dec 1998/Jul 2001: Research Fellow at the CNR Center of Molecular Biology, Rome
-1997/1998: Post-doc Fellow at Accademia Nazionale dei Lincei, Rome

1) Hydrogen sulfide metabolism: biochemistry and impact on health and diseases
2) Gasotransmitters and cellular bioenergetics
3) Energy metabolism and antioxidant defence in microorganisms: looking for drug targets

Research activity in the following foreign laboratories:
▪ University of Lisbon, Lisbon - Oeiras, Portugal
(Lab prof. M. Teixeira e dr. J.B. Vicente, Instituto de Tecnologia Quimica e Biologica - Science Faculty / 7–17 May 1997; 29 Sep – 7 Oct 2002; 20–27 Jul 2003; 10–17 Apr 2005; 2–9 Jul 2005; 12–19 Feb 2006; 9-22 Sep 2007; 6-19 Jul 2008; 23 Nov - 3 Dic 2011; 12-19 Jul 2012; 18-29 Nov 2012; 23 Jun- 2 Jul 2013; 1-9 Nov 2013; 20-29 Oct 2014; 7-13 Jun 2015; 1-8 Nov 2015; 14-21 Jun 2016; 2-7 Dec 2016; 13-20 Oct 2019)
▪ University of Helsinki, Helsinki, Finland
(Lab prof. M. Wikström, Institute of Biotechnology / 25 Nov – 4 Dec 2002).
▪ University of Frankfurt, Frankfurt, Germany
(Laboratorio prof. B. Ludwig, Institute of Biochemistry / 5-23 Jul 1999; 9–22 Jul 2000).
▪ University of East Anglia, Norwich, UK
(Lab prof. C. Greenwood, School of Biological Sciences / 23–28 Jun 1996).
▪ NIH, Bethesda, MD, USA
(Lab prof. E. Henry, Dept. of Health and Human Services / 28 Jun – 7 Jul 1995; 12–22 Feb 1996).
▪ University of Groningen, Groningen, The Netherlands
(Lab prof. W.N. Konings, Dept. of Microbiology / 5–10 Dec 1994).
▪ Medical University of Luebeck, Luebeck, Germany
(Lab prof. G. Schaefer, Institute of Biochemistry / 10-23 Oct 1993; 4–11 Mar 1995)
▪ University of Essex, Colchester, UK
(Lab prof. M.T. Wilson, Dept. of Chemistry and Biological Chemistry / 24-30 Jun1991; 11–16 Sep 1994)
▪ European Laboratory of Molecular Biology (EMBL), Heidelberg, Germany
(Lab dr. M. Saraste / 18 Nov – 14 Dec 1991)

-João Vicente, Miguel Teixeira & Ligia Saraiva (University of Lisbon, P)

- Scopus (N. publications: 98; Citations: 4.343; H-index = 38)
- WoS (N. publications: 100; Citations: 4.004; H-index = 37)
- Google Scholar (N. publications: 132; Citations: 5.637; H-index = 44)

- since 2005: Visiting Professor at ITQB, New University of Lisbon (P)
- since 2012: Teaching Board Member of the PhD in Biochemistry, Sapienza University of Rome
- 2018 to 2021: Lecturer in charge, Course of Pharmacy, Sapienza University of Rome
- since 2014: National Scientific Qualification (Abilitazione Scientifica Nazionale - ASN) to Full Professor (SSD E1/05 - Biochemistry)
- since 2007: Evaluator in PhD thesis defences or mid-term exams at Universities of Stockholm (Sweden), Lisbon (Portugal), Aarhus (Denmark) and Amsterdam (The Netherlands) (8 sessions)
- 2000 to 2017: Lecturer in charge, Course of Biomedical Laboratory Techniques, Sapienza University of Rome

- PRIN Project (MUR- 20224BYR59) - 'Hydrogen sulfide metabolism in Pseudomonas aeruginosa (patho)physiology' [28/09/2023 - 27/09/2025]
- PRIN Project (MIUR - 20158EB2CM_003) 'Hydrogen sulphide as a new player of Amyotrophic Lateral Sclerosis: focus on mitochondrial homeostasis' (05/02/2017 - 04/02/2020)
- PNR-CNR Ageing Project (MIUR) 'Role of redox mechanisms and protein accumulation in age-related diseases' (2012-2018).
- Bilateral CNR-FCT project (Portugal) 'Hydrogen sulfide metabolism in colon-cancer' (2015 – 2016).
- Bilateral CNR-FCT project (Portugal) 'Interaction between gasotransmitters (H2S, NO and CO) and metalloproteins: physiological relevance' (2013 – 2014).
- FIRB project (Futuro in Ricerca 2008, MIUR - RBFR08F41U). 'Novel mechanisms of the microbial stress response to oxidative and nitrosative stress' (Dec 2010 – Nov 2013).
- Bilateral CNR-FCT project (Portugal). 'Response to oxidative stress in the anaerobic protozoa Giardia intestinalis and Entamoeba histolytica' (2011 – 2012).
- Research grant 2009 of the European Society for Microbiology and Infectious Diseases (ESCMID). 'Response of the human parasite Giardia intestinalis to oxidative and nitrosative stress' (Mar 2009 – Feb 2011.
- Bilateral CNR-GRICES project (Portugal). 'Nitric oxide detoxification in pathogenic microorganisms: structure-function relationships in flavodiiron proteins' (2005 – 2008).
- CNR project (commessa a tema libero). 'Mechanisms of nitric oxide detoxification in pathogenic microrganisms: role of flavodiiron proteins' (2005)
- MIUR project (Giovani Ricercatori – Year 2002). 'Cytochrome c oxidase: role of proton transfer pathways in the intramolecolar electron transfer' (Oct 2002 –Oct 2003).

04/2020 – to date: Director of CNR Institute of Molecular Biology and Pathology
02/2010 – 2015: Scientific Director of the CNR project 'Structure, function and design of proteins, nucleic acids and supermolecular complexes'. CNR Department of Life Sciences.
2005-2009/2014-2018: Executive board member of the Italian Group of Bioenergetics and Biomembranes

Co-organizer of the following initiatives:
- Redox Webinar Series [2022 to date]
- International Workshop on Biochemistry, Physiology and Pharmacology of Oxidative Stress – Rome 2-4/07/2015 - 38° GIBB annual meeting. Rome 24-27/05/2011
- 32° GIBB annual meeting. Rome 13-15/06/2005
- 29° GIBB annual meeting. Rome 2-4/05/2002 - International meeting on 'Structure and Function of Terminal Oxidases'. Rome/Rieti - May 1994

- Reviewer of grant proposals and academic positions for the following Institutions:
MIUR - FIRB/SIR/Giovani Montalcini/VQR 2011-2014 (since 2013 to date)
NSERC - Canada (2023)
MRC - UK (2014, 2022)
Swiss National Foundation - CH (2019, 2021, 2022)
BBSRC – UK (2020)
National Science Foundation - USA (2019)
NWO - NL (2010)
Trent University - Canada (2017)
University of Padova (2016)
University of Bordeaux - F (2015)

- PloS ONE Academic Editor (2013-2022).
- Guest Editor for Antioxidants (2020-2021)

- Reviewer for the following journals:
Nature Communications, Nature Chemical Biology, Science Advances, The Journal of Biological Chemistry, Biochemistry, Antioxidants & Redox Signaling, Redox Biology, Free Radical in Biology & Medicine, Antioxidants, Scientific Reports, PLoS Pathogens, Biochimica et Biophysica Acta - Bioenergetics, FEBS Letters, FEBS OpenBio, Molecular Microbiology, Antimicrobial Agents and Chemotherapy, Microbiology, Journal of Bacteriology, Journal of Parasitology, Experimental Parasitology, Tropical Biomedicine, International Journal of Molecular Sciences, Parasitology Open, Biochimie, International Journal of Parasitology, Applied Microbiology and Biotechnology, Journal of Biological Inorganic Chemistry, Nitric Oxide, Current Opinion in Chemical Biology, Molecular Pharmacology, Trends in Parasitology.

-2005 to date: Visiting Professor at ITQB, New University of Lisbon, Portugal
-2015 to date: Academician of the Medical Academy of Medicine of Rome
-2014-2018: Vice-President of the Italian Group of Bioenergetics and Biomembranes GIBB)
-2004: ‘Maria Teresa Tessori Roncaglia e Eugenio Mari’ award – Accademia Nazionale dei Lincei
-2002: ‘Mc Graw Hill’ award – Italian Society of Biochemistry and Molecular Biology
-1997/1998: Fellowship in Biophysics from Centro Interdisciplinare Linceo - Accademia Nazionale dei Lincei
-1997: PhD thesis award – Fondazione Cenci Bolognetti
-1991: ‘Luca Barone’ award – Accademia Nazionale dei Lincei

-2018: Bacterial Electron Transfer Processes and their Regulation, Saint Tropez (F)
-2016: XIX International Conference on Oxygen Binding and Sensing Proteins, Hamburg (D)
-2016: XIV Congress of the Italian Federation of Life Sciences, Rome (I)
-2016: 19th European Bioenergetics Conference, Riva del Garda (I)
-2016: 4th International Conference on the Biology of Hydrogen Sulfide, Napoli (I)
-2015: Bacterial Electron Transfer Processes and their Regulation, Vimeiro (P)
-2015: Closing Action conference of the European Network on Gasotransmitters, Athens, (GRE)
-2014: 13th International Conference of Parasitology, Mexico City (MEX)
-2014: 18th European Bioenergetics Conference, Lisbon (P)
-2014: 18th International Conference on Oxygen-Binding and Sensing Proteins, Sheffield (UK)
-2012: Satellite Symposium on Microbes and NO of the 7th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide, Edinburgh (UK)
-2012: IV International Giardia and Cryptosporidium Conference, Wellington (NZ)
-2011: 9th Indo-Italian Workshop on Chemistry and Biology of Antioxidants, New Delhi (IND)
-2008: 19th Annual Molecular Parasitology Meeting, Woods Hole (USA)
-2007: 1st Summer School on Mitochondrial Respiratory Physiology, Schroecken (A)
-2006: Young Researchers Forum, 8th European Biological Inorganic Chemistry, Aveiro (P)
-2005: International Conference on Mitochondria, Bari (I)
-2004: 13th European Bioenergetics Conference, Pisa (I)
-2002: 4th Course of the Portuguese Biophysical Society, Santarem (P)
-2000: Villa Vigoni Conference, Loveno di Menaggio (I)
-2000: 18th Sigrid Juselius International Symposium, Helsinki (FIN)

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma