ALESSANDRA BONAMORE

Professore associato


email: alessandra.bonamore@uniroma1.it
telefono: 0692727649
edificio: CU027
stanza: 208

ESPERIENZA LAVORATIVA
[ 2017 – oggi ] Professore Associato, Biochemica BIO/10
Sapienza, Università di Roma
Città: Rome
Paese: Italia
Attività didattica e di ricerca
[ 2008 – 2017 ] Ricercatore, Biologia Molecolare BIO/11
Sapienza, Università di Roma
Città: Rome
Paese: Italia
Attività didattica e di ricerca
Assegnista di Ricerca
Sapienza, Università di Roma
Città: Rome
Paese: Italia
Attività di ricerca

FORMAZIONE
[ 2001 – 2004 ] PhD in Biochemistry
Sapienza, Università di Roma
Città: Rome
Paese: Italia
[ 1994 – 2020 ] Laurea in Scienze Biologiche
Votazione 110/110 e lode
Sapienza, Università di Roma
Città: Rome
Paese: Italia

ATTIVITA’ SCIENTIFICA
Ingegnerizzazione di proteine per la biocatalisi. Questa linea di ricerca è principalmente focalizzata su emoglobine batteriche e su enzimi appositamente progettati per applicazioni biocatalitiche, con una particolare attenzione alla loro rilevanza industriale e biotecnologica. L’indagine si estende alla produzione ecosostenibile di intermedi farmaceutici e sostanze biologicamente attive utilizzando enzimi ricombinanti, tra cui l’alcool allilico deidrogenasi, pictet-spenglerasi, preniltransferasi e citocromo P450, ma anche enzimi purificati derivati da piante, come le amino ossidasi.
Ingegnerizzazione di protein per il drug delivery. Questa linea di ricerca è incentrata sullo sviluppo di nanovettori innovativi a base di ferritina per la somministrazione mirata di agenti terapeutici e di imaging e terapie rivolti contro cellule tumorali. Particolare attenzione è dedicata a facilitare la somministrazione mirata di farmaci non convenzionali, tra cui proteine terapeutiche, peptidi e piccole molecole di RNA. L'attività di ricerca è stata condotta nell'ambito di diversi progetti, tra cui due progetti europei (X-Probe (637295) e ProMeTeus (823780)), tre progetti PRIN (2004, 2008 e 2022), un progetto FIRB (2008).

TEACHING ACTIVITY
Attuale attività didattica
Corso, facoltà, luogo.
Biologia Molecolare, Corso di Biochimica, Laurea in Medicina e Chirurgia E – Facoltà di Farmacia e Medicina - Sapienza Università di Roma - Polo Pontino.
Biologia Molecolare, Corso integrato in Basi Biochimiche delle Scienze Diagnostiche, Laurea in Tecniche di Laboratorio Biomedico – Facoltà di Farmacia e Medicina - Sapienza Università di Roma - Polo Pontino.
Biochimica, Corso integrato in Basi Biochimiche delle Scienze Diagnostiche, Laurea in Tecniche di Laboratorio Biomedico – Facoltà di Farmacia e Medicina - Sapienza Università di Roma - Polo Pontino.
Gestione e Innovazione nelle Biotecnologie, Laurea in Comunicazione Scientifica Biomedica – Corso Interfacoltà (Farmacia e Medicina, Scienze Politiche, Sociologia, Comunicazione) - Sapienza Università di Roma – Roma.


Produzione scientifica

11573/1718036 - 2024 - Ferritin-based disruptor nanoparticles: A novel strategy to enhance LDL cholesterol clearance via multivalent inhibition of PCSK9–LDL receptor interaction
Incocciati, A.; Cappelletti, C.; Masciarelli, S.; Liccardo, F.; Piacentini, R.; Giorgi, A.; Bertuccini, L.; De Berardis, B.; Fazi, F.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Bognor Regis: Wiley Cambridge: Cambridge University Press) pp. 1-12 - issn: 1469-896X - wos: WOS:001292295000001 (0) - scopus: 2-s2.0-85201427486 (1)

11573/1727178 - 2024 - Challenges in Exploiting Human H Ferritin Nanoparticles for Drug Delivery: Navigating Physiological Constraints
Macone, A.; Cappelletti, C.; Incocciati, A.; Piacentini, R.; Botta, S.; Boffi, A.; Bonamore, A. - 01g Articolo di rassegna (Review)
rivista: WILEY INTERDISCIPLINARY REVIEWS. NANOMEDICINE AND NANOBIOTECHNOLOGY (Hoboken, NJ : John Wiley & Sons) pp. 1-15 - issn: 1939-0041 - wos: (0) - scopus: 2-s2.0-85209123525 (0)

11573/1700809 - 2024 - Design of protein-binding peptides with controlled binding affinity: the case of SARS-CoV-2 receptor binding domain and angiotensin-converting enzyme 2 derived peptides
Parisi, G.; Piacentini, R.; Incocciati, A.; Bonamore, A.; Macone, A.; Rupert, J.; Zacco, E.; Miotto, M.; Milanetti, E.; Tartaglia, G. G.; Ruocco, G.; Boffi, A.; Di Rienzo, L. - 01a Articolo in rivista
rivista: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-889X - wos: WOS:001144542200001 (2) - scopus: 2-s2.0-85182672420 (2)

11573/1676431 - 2023 - Ferritin-coated SPIONs as new cancer cell targeted magnetic nanocarrier
Affatigato, L.; Licciardi, M.; Bonamore, A.; Martorana, A.; Incocciati, A.; Boffi, A.; Militello, V. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1163- - issn: 1420-3049 - wos: WOS:000929543400001 (5) - scopus: 2-s2.0-85147895486 (7)

11573/1676430 - 2023 - Engineered Ferritin with Eu3+ as a Bright Nanovector: A Photoluminescence Study
Affatigato, L.; Sciortino, A.; Sancataldo, G.; Incocciati, A.; Piacentini, R.; Bonamore, A.; Cannas, M.; Messina, F.; Licciardi, M.; Militello, V. - 01a Articolo in rivista
rivista: PHOTOCHEMISTRY AND PHOTOBIOLOGY (American Society of Photobiology:1021 15th Street, Suite 9:Augusta, GA 30901:(706)722-7511, EMAIL: executive.office@asanet.org, INTERNET: http://www.asanet.org, Fax: (706)722-7515 Editore precedente:Pergamon Press.) pp. 1218-1224 - issn: 0031-8655 - wos: WOS:000907573000001 (0) - scopus: 2-s2.0-85145504623 (0)

11573/1688526 - 2023 - Harnessing buffer solutions to modify the association state of Ferritin nanoparticles
Incocciati, A.; Cappelletti, C.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
rivista: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 414- - issn: 2297-8739 - wos: WOS:001039630400001 (0) - scopus: 2-s2.0-85166399696 (0)

11573/1692513 - 2023 - Hydrophobicity‐enhanced ferritin nanoparticles for efficient encapsulation and targeted delivery of hydrophobic drugs to tumor cells
Incocciati, Alessio; Kubeš, Jan; Piacentini, Roberta; Cappelletti, Chiara; Botta, Sofia; Bertuccini, Lucia; Šimůnek, Tomáš; Boffi, Alberto; Macone, Alberto; Bonamore, Alessandra - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Bognor Regis: Wiley Cambridge: Cambridge University Press) pp. - - issn: 1469-896X - wos: WOS:001107660800001 (7) - scopus: 2-s2.0-85177462333 (7)

11573/1648657 - 2022 - Immobilization of Lathyrus cicera amine oxidase on magnetic microparticles for biocatalytic applications
Di Fabio, Elisa; Iazzetti, Antonia; Incocciati, Alessio; Caseli, Valentina; Fabrizi, Giancarlo; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 6529- - issn: 1422-0067 - wos: WOS:000818208500001 (3) - scopus: 2-s2.0-85131542371 (4)

11573/1615111 - 2022 - Rapid and simultaneous determination of free aromatic carboxylic acids and phenols in commercial juices by GC-MS after ethyl chloroformate derivatization
Incocciati, A.; Di Fabio, E.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
rivista: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 9- - issn: 2297-8739 - wos: WOS:000758392000001 (2) - scopus: 2-s2.0-85123755357 (4)

11573/1660680 - 2022 - Unlocking the treasure box: the role of HEPES buffer in disassembling an uncommon ferritin nanoparticle
Incocciati, A; Bertuccini, L; Boffi, A; Macone, A; Bonamore, A - 01a Articolo in rivista
rivista: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 222- - issn: 2297-8739 - wos: WOS:000845227300001 (3) - scopus: 2-s2.0-85136693526 (3)

11573/1621727 - 2021 - Biocatalytic production of aldehydes: exploring the potential of lathyrus cicera amine oxidase
Di Fabio, E.; Incocciati, A.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 1540- - issn: 2218-273X - wos: WOS:000828673600001 (4) - scopus: 2-s2.0-85117071209 (5)

11573/1551118 - 2021 - Exciplex formation in lipid-bound Escherichia coli flavohemoglobin
Marcelli, A.; Patrizi, B.; Bonamore, A.; Boffi, A.; Becucci, M.; Foggi, P. - 01a Articolo in rivista
rivista: CHEMPHYSCHEM (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1134-1140 - issn: 1439-4235 - wos: WOS:000644988900001 (0) - scopus: 2-s2.0-85105032084 (0)

11573/1554362 - 2021 - Self-assembling ferritin-dendrimer nanoparticles for targeted delivery of nucleic acids to myeloid leukemia cells
Palombarini, F.; Masciarelli, S.; Incocciati, A.; Liccardo, F.; Di Fabio, E.; Iazzetti, A.; Fabrizi, G.; Fazi, F.; Macone, A.; Bonamore, A.; Boffi, A. - 01a Articolo in rivista
rivista: JOURNAL OF NANOBIOTECHNOLOGY (London : BioMed Central.) pp. 1-12 - issn: 1477-3155 - wos: WOS:000660095400001 (40) - scopus: 2-s2.0-85107462102 (44)

11573/1447230 - 2020 - Ethylchloroformate derivatization for GC-MS analysis of resveratrol isomers in red wine
Di Fabio, E.; Incocciati, A.; Palombarini, F.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 4603- - issn: 1420-3049 - wos: WOS:000583012000001 (6) - scopus: 2-s2.0-85092519779 (6)

11573/1448485 - 2020 - Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice
Kiraga, L.; Cerutti, G.; Braniewska, A.; Strzemecki, D.; Sas, Z.; Boffi, A.; Savino, C.; Montemiglio, L. C.; Turnham, D.; Seaton, G.; Bonamore, A.; Clarkson, R.; Dabkowski, A. M.; Paisey, S. J.; Taciak, B.; Kucharzewska, P.; Rygiel, T. P.; Krol, M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-15 - issn: 1661-6596 - wos: WOS:000554130900001 (1) - scopus: 2-s2.0-85087932608 (2)

11573/1448470 - 2020 - Ferritin nanocages for protein delivery to tumor cells
Palombarini, F.; Di Fabio, E.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 825- - issn: 1420-3049 - wos: WOS:000522454500061 (47) - scopus: 2-s2.0-85079643167 (50)

11573/1316071 - 2019 - A gas chromatographic–mass spectrometric method for the simultaneous determination of resveratrol isomers and 2,4,6-trihydroxyphenanthrene in red wines exposed to UV-light
Francioso, Antonio; Laštovičková, Lenka; Mosca, Luciana; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 11752-11757 - issn: 0021-8561 - wos: WOS:000492802400022 (12) - scopus: 2-s2.0-85073189936 (12)

11573/1313577 - 2019 - Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells
Macone, A.; Masciarelli, S.; Palombarini, Federica; Quaglio, D.; Boffi, A.; Trabuco, M. C.; Baiocco, P.; Fazi, F.; Bonamore, A. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11749- - issn: 2045-2322 - wos: WOS:000480517100029 (46) - scopus: 2-s2.0-85070764634 (51)

11573/1316082 - 2019 - Application of crossflow ultrafiltration for scaling up the purification of a recombinant ferritin
Palombarini, F.; Ghirga, F.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
rivista: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. - - issn: 1046-5928 - wos: WOS:000481561700007 (14) - scopus: 2-s2.0-85068569345 (16)

11573/1121880 - 2018 - Excimer based fluorescent pyrene-ferritin conjugate for protein oligomerization studies and imaging in living cells
Benni, Irene; Trabuco, Matilde Cardoso; Di Stasio, Enrico; Arcovito, Alessandro; Boffi, Alberto; Malatesta, Francesco; Bonamore, Alessandra; De Panfilis, Simone; De Turris, Valeria; Baiocco, Paola - 01a Articolo in rivista
rivista: RSC ADVANCES (London: Royal Society of Chemistry) pp. 12815-12822 - issn: 2046-2069 - wos: WOS:000429450000038 (12) - scopus: 2-s2.0-85045180344 (13)

11573/1175774 - 2018 - Engineered ferritin for lanthanide binding
Calisti, Lorenzo; Cardoso Trabuco, Matilde; Boffi, Alberto; Testi, Claudia; Montemiglio, Linda Celeste; Des Georges, Amédée; Benni, Irene; Ilari, Andrea; Taciak, Bartłomiej; Białasek, Maciej; Rygiel, Tomasz; Krol, Magdalena; Baiocco, Paola; Bonamore, Alessandra - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000441452200019 (25) - scopus: 2-s2.0-85051486677 (25)

11573/928790 - 2017 - Humanized archaeal ferritin as a tool for cell targeted delivery
De Turris, Valeria; Cardoso Trabuco, Matilde; Peruzzi, Giovanna; Boffi, Alberto; Testi, Claudia; Vallone, Beatrice; Celeste Montemiglio, Linda; Georges, Amédée Des; Calisti, Lorenzo; Benni, Irene; Bonamore, Alessandra; Baiocco, Paola - 01a Articolo in rivista
rivista: NANOSCALE (Cambridge,UK: RCS PUBLISHING -Royal Society of Chemistry) pp. 647-655 - issn: 2040-3364 - wos: WOS:000394780200022 (30) - scopus: 2-s2.0-85008894536 (31)

11573/1021474 - 2017 - Green routes for the production of enantiopure benzylisoquinoline alkaloids
Ghirga, Francesca; Bonamore, Alessandra; Calisti, Lorenzo; D'acquarica, Ilaria; Mori, Mattia; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000416811300234 (10) - scopus: 2-s2.0-85034960303 (11)

11573/867977 - 2016 - Mapping the amide I absorption in single bacteria and mammalian cells with resonant infrared nanospectroscopy
Baldassarre, Leonetta; Giliberti, Valeria; Rosa, Alessandro; Ortolani, Michele; Bonamore, Alessandra; Baiocco, Paola; Kjoller, K.; Calvani, Paolo; Nucara, Alessandro - 01a Articolo in rivista
rivista: NANOTECHNOLOGY (Bristol, United Kingdom: IOP Publishing Limited) pp. 075101- - issn: 0957-4484 - wos: WOS:000368935000006 (55) - scopus: 2-s2.0-84955465361 (52)

11573/884656 - 2016 - A novel enzymatic strategy for the synthesis of substituted tetrahydroisoquinolines
Bonamore, Alessandra; Calisti, Lorenzo; Calcaterra, Andrea; Ismail, Omar Habib; Gargano, Maurizio; D'acquarica, Ilaria; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
rivista: CHEMISTRYSELECT (John Wiley & Sons, Inc) pp. 1525-1528 - issn: 2365-6549 - wos: WOS:000395407100002 (19) - scopus: 2-s2.0-85029937881 (21)

11573/928785 - 2016 - Probing bulky ligand entry in engineered archaeal ferritins
Calisti, Lorenzo; Benni, Irene; Cardoso Trabuco, Matilde; Baiocco, Paola; Ruzicka, Barbara; Boffi, Alberto; Falvo, Elisabetta; Malatesta, Francesco; Bonamore, Alessandra - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 450-456 - issn: 0304-4165 - wos: WOS:000392680200042 (11) - scopus: 2-s2.0-85001820140 (11)

11573/821477 - 2015 - A Novel Direct Method for Determination of Riboflavin in Alcoholic Fermented Beverages
Bonamore, Alessandra; Gargano, Maurizio; Calisti, Lorenzo; Francioso, Antonio; Mosca, Luciana; Boffi, Alberto; Federico, Rodolfo - 01a Articolo in rivista
rivista: FOOD ANALYTICAL METHODS (New York, NY : Springer Science and Business Media) pp. - - issn: 1936-9751 - wos: WOS:000371257000004 (6) - scopus: 2-s2.0-84959075759 (6)

11573/839384 - 2015 - Electrocatalytic interconversion of NADH and NAD+ by Escherichia coli flavohemoglobin
Shipovskov, S.; Bonamore, Alessandra; Boffi, Alberto; Ferapontova, E. E. - 01a Articolo in rivista
rivista: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 16096-16098 - issn: 1359-7345 - wos: WOS:000363666000018 (11) - scopus: 2-s2.0-84946041332 (13)

11573/675815 - 2014 - New Engineered Archaeoglobus fulgidus Ferritin as Supramolecular Biotransducer for SPR-based Biosensors
Boffi, Alberto; Bonamore, Alessandra; Sanzo', Gabriella; Tortolini, Cristina; Favero, Gabriele; Mazzei, Franco - 04a Atto di comunicazione a congresso
congresso: BioSensors 2014 (Melbourne)
libro: Proceedings of the 24th World Anniversary Congress on Biosensors - ()

11573/556311 - 2014 - Molecular basis of thermal stability in truncated (2/2) hemoglobins
Juan P., Bustamante; Bonamore, Alessandra; Alejandro D., Nadra; Natascia, Sciamanna; Boffi, Alberto; Darío A., Estrin; Leonardo, Boechi - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0304-4165 - wos: WOS:000338402400019 (9) - scopus: 2-s2.0-84899789832 (9)

11573/548142 - 2014 - Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins
Juan P., Bustamante; Stefania, Abbruzzetti; Agnese, Marcelli; Diego, Gauto; Leonardo, Boechi; Bonamore, Alessandra; Boffi, Alberto; Stefano, Bruno; Alessandro, Feis; Paolo, Foggi; Dario A., Estrin; Cristiano, Viappiani - 01a Articolo in rivista
rivista: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. 1234-1245 - issn: 1520-6106 - wos: WOS:000331153800007 (20) - scopus: 2-s2.0-84893831206 (24)

11573/782766 - 2014 - Interplay of the H-bond donor-acceptor role of the distal residues in hydroxyl ligand stabilization of Thermobifida fusca truncated hemoglobin
Nicoletti, F. P.; Bustamante, J. P.; Droghetti, E.; Howes, B. D.; Fittipaldi, M.; Bonamore, Alessandra; Baiocco, P.; Feis, A.; Boffi, Alberto; Estrin, D.; Smulevich, G. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 8021-8030 - issn: 0006-2960 - wos: WOS:000347437700004 (14) - scopus: 2-s2.0-84920094601 (14)

11573/782772 - 2014 - Role of local structure and dynamics of small ligand migration in proteins: A study of a mutated truncated hemoprotein from Thermobifida fusca by time resolved MIR spectroscopy
Patrizi, B.; Lapini, A.; Di Donato, M.; Marcelli, A.; Lima, M.; Righini, R.; Foggi, P.; Baiocco, P.; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. 9209-9217 - issn: 1520-6106 - wos: WOS:000340223000009 (5) - scopus: 2-s2.0-84905731127 (5)

11573/508130 - 2013 - Direct electrochemistry and Os-polymer-mediated bioelectrocatalysis of NADH oxidation by Escherichia coli flavohemoglobin at graphite electrodes
Maciej, Sosna; Bonamore, Alessandra; Gorton, Lo; Boffi, Alberto; Elena E., Ferapontova - 01a Articolo in rivista
rivista: BIOSENSORS & BIOELECTRONICS (Barking: Elsevier Science Publishers) pp. 219-224 - issn: 0956-5663 - wos: WOS:000309404100011 (20) - scopus: 2-s2.0-84871666727 (30)

11573/515797 - 2013 - H-bonding networks of the distal residues and water molecules in the active site of Thermobifida fusca hemoglobin
Nicoletti, Fp; Droghetti, E; Howes, Bd; Bustamante, Jp; Bonamore, Alessandra; Sciamanna, Natascia; Estrin, Da; Feis, A; Boffi, Alberto; Smulevich, G. - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0006-3002 - wos: WOS:000323191800025 (20) - scopus: 2-s2.0-84884641056 (21)

11573/468132 - 2012 - Enzymatic, stereoselective synthesis of (S)-norcoclaurine.
Bonamore, Alessandra; Macone, Alberto - 02a Capitolo o Articolo
libro: Practical Methods for Biocatalysis and Biotransformations 2 - (9781119991397)

11573/508757 - 2012 - C–C Bond Formation and Decarboxylation
Bonamore, Alessandra; Macone, Alberto; Kroutil, Wolfgang; Seisser, Birgit; Lammens, Tijs M.; De Biase, Daniela; Franssen, Maurice C. R.; Scott, Elinor L.; Sanders, Johan P. M.; Miyamoto, Kenji; Kourist, Robert; Yoshida, Shosuke; Ohta, Hiromichi; Tian, Jie; Li, Heng; Gao, Wen-Yun; Shanmuganathan, Saravanakumar; Natalia, D.; Greiner, Lasse; Domínguez De Maria, Pablo; He, Yan-Hong; Guan, Zhi; Cai, Jian-Feng - 02a Capitolo o Articolo
libro: Practical Methods for Biocatalysis and Biotransformations 2 - (9781119943426; 9781119991397)

11573/484812 - 2012 - Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca.
Marcelli, A; Abbruzzetti, S; Bustamante, Jp; Feis, A; Bonamore, Alessandra; Boffi, Alberto; Gellini, C; Salvi, Pr; Estrin, Da; Bruno, S; Viappiani, C; Foggi, P. - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. 1-12 - issn: 1932-6203 - wos: WOS:000306461800024 (21) - scopus: 2-s2.0-84863638846 (22)

11573/406737 - 2012 - Production of bioactive compounds: the importance of Pictet-Spengler reaction in the XXI century
P., Menendez; D'acquarica, Ilaria; G., Delle Monache; Ghirga, Francesca; Calcaterra, Andrea; Barba, Marco; Macone, Alberto; Boffi, Alberto; Bonamore, Alessandra; Botta, Bruno - 02a Capitolo o Articolo
libro: Bioactive Principles from Plants and Drug Discovery: Practice and Perspectives - (9780470582268)

11573/390983 - 2011 - The optical spectra of fluoride complexes can effectively probe H-bonding interactions in the distal cavity of heme proteins
Enrica, Droghetti; Francesco P., Nicoletti; Bonamore, Alessandra; Sciamanna, Natascia; Boffi, Alberto; Alessandro, Feis; Giulietta, Smulevich - 01a Articolo in rivista
rivista: JOURNAL OF INORGANIC BIOCHEMISTRY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 1338-1343 - issn: 0162-0134 - wos: WOS:000295423700010 (23) - scopus: 2-s2.0-84860389795 (23)

11573/442627 - 2011 - Fluoride as a Probe for H-Bonding Interactions in the Active Site of Heme Proteins: The Case of Thermobifida fusca Hemoglobin
Francesco P., Nicoletti; Enrica, Droghetti; Leonardo, Boechi; Bonamore, Alessandra; Sciamanna, Natascia; Dario A., Estrin; Alessandro, Feis; Boffi, Alberto; Giulietta, Smulevich - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 20970-20980 - issn: 0002-7863 - wos: WOS:000298571600049 (29) - scopus: 2-s2.0-84555177994 (29)

11573/226895 - 2010 - Unusual proximal heme pocket geometry in the deoxygenated Thermobifida fusca: A combined spectroscopic investigation
Alessandro, Arcovito; Bonamore, Alessandra; Jean Louis, Hazemann; Boffi, Alberto; D'angelo, Paola - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-7 - issn: 0301-4622 - wos: WOS:000274709900001 (4) - scopus: 2-s2.0-75549089304 (4)

11573/226629 - 2010 - Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme
Bonamore, Alessandra; Barba, Marco; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 2070-2078 - issn: 1420-3049 - wos: WOS:000277147400002 (34) - scopus: 2-s2.0-77951848665 (39)

11573/376102 - 2010 - An enzymatic, stereoselective synthesis of (S)-norcoclaurine
Bonamore, Alessandra; Rovardi, Irene; Gasparrini, Francesco; Baiocco, Paola; Barba, Marco; Molinaro, Carmela; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
rivista: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1623-1627 - issn: 1463-9262 - wos: WOS:000281613900018 (51) - scopus: 2-s2.0-77956389962 (57)

11573/377080 - 2010 - Heme Pocket Structural Properties of a Bacterial Truncated Hemoglobin from Thermobifida fusca
Enrica, Droghetti; Francesco Paolo, Nicoletti; Bonamore, Alessandra; Leonardo, Boechi; Pau Arroyo, Manez; Dario A., Estrin; Boffi, Alberto; Giulietta, Smulevich; Alessandro, Feis - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 10394-10402 - issn: 0006-2960 - wos: WOS:000284975000006 (24) - scopus: 2-s2.0-78650113583 (24)

11573/228330 - 2010 - Sulfide Binding Properties of Truncated Hemoglobins
Francesco P., Nicoletti; Alessandra, Comandini; Bonamore, Alessandra; Leonardo, Boechi; Fernando Martin, Boubeta; Alessandro, Feis; Giulietta, Smulevich; Boffi, Alberto - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 2269-2278 - issn: 0006-2960 - wos: WOS:000275227000019 (55) - scopus: 2-s2.0-77949408968 (61)

11573/224347 - 2009 - (R)-1-Arylethanols from aryl iodides through a two-step one-pot enantioselective chemoenzymatic process
Cacchi, Sandro; Roberto, Cirilli; Fabrizi, Giancarlo; Simona, Sgalla; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 184-187 - issn: 1381-1177 - wos: WOS:000272064600012 (9) - scopus: 2-s2.0-72049130562 (10)

11573/229201 - 2009 - Structural basis of enzymatic (S)-norcoclaurine biosynthesis
Ilari, Andrea; Franceschini, S; Bonamore, Alessandra; Arenghi, F; Botta, Bruno; Macone, Alberto; Pasquo, A; Bellucci, L; Boffi, Alberto - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 897-904 - issn: 0021-9258 - wos: WOS:000262122900024 (97) - scopus: 2-s2.0-59449099013 (104)

11573/226721 - 2009 - Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WT
Macone, Alberto; Lendaro, Eugenio; Alessandra, Comandini; Rovardi, Irene; Matarese, Rosa Marina; Antonio, Carraturo; Bonamore, Alessandra - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 6003-6007 - issn: 0968-0896 - wos: WOS:000268762900027 (13) - scopus: 2-s2.0-68149144266 (13)

11573/360869 - 2009 - Peroxidase-like activity of Thermobifida fusca hemoglobin: The oxidation of dibenzylbutanolide
Torge, Roberta; Alessandra, Comandini; Bruno, Catacchio; Bonamore, Alessandra; Botta, Bruno; Boffi, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 303-308 - issn: 1381-1177 - wos: WOS:000272064600031 (13) - scopus: 2-s2.0-72049095862 (15)

11573/229453 - 2008 - Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum
Alessandra, Pasquo; Bonamore, Alessandra; Stefano, Franceschini; Macone, Alberto; Boffi, Alberto; Ilari, Andrea - 01a Articolo in rivista
rivista: ACTA CRYSTALLOGRAPHICA. SECTION F, STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS (Malden, MA : Published for International Union of Crystallography by Blackwell) pp. 281-283 - issn: 1744-3091 - wos: WOS:000254473200014 (21) - scopus: 2-s2.0-41949092539 (24)

11573/141021 - 2008 - Globin interactions with lipids and membranes
Antonio Di, Giulio; Bonamore, Alessandra - 01a Articolo in rivista
rivista: METHODS IN ENZYMOLOGY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 239-253 - issn: 0076-6879 - wos: WOS:000253294600013 (10) - scopus: 2-s2.0-42949117860 (10)
libro: Globins and Other Nitric Oxide-Reactive Proteins, Part A - (9780123742773)

11573/226948 - 2008 - Flavohemoglobin: structure and reactivity.
Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 19-28 - issn: 1521-6543 - wos: WOS:000252522000004 (83) - scopus: 2-s2.0-42949138420 (89)

11573/360024 - 2008 - The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity
Ilari, Andrea; Bonamore, Alessandra; Stefano, Franceschini; Fiorillo, Annarita; Boffi, Alberto; Gianni, Colotti - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 2065-2075 - issn: 0887-3585 - wos: WOS:000255920600037 (23) - scopus: 2-s2.0-44349132154 (26)

11573/362080 - 2007 - A novel chimera: the "truncated hemoglobin-antibiotic monooxygenase" from Streptomyces avermitilis.
Bonamore, Alessandra; Attili, A; Arenghi, F; B., Catacchio; Chiancone, Emilia; Morea, V; Boffi, Alberto - 01a Articolo in rivista
rivista: GENE (Amsterdam Netherlands: Elsevier BV) pp. 52-61 - issn: 0378-1119 - wos: WOS:000248784200007 (13) - scopus: 2-s2.0-34447537731 (14)

11573/239779 - 2007 - Folding propensity and biological activity of peptides: New insights from conformational properties of a novel peptide derived from Vitreoscilla haemoglobin.
Bozzi, A; Coccia, C; Di Giulio, A; Rinaldi A., C; Amadei, A; Mignogna, Giuseppina; Bonamore, Alessandra; Feis, A; Aschi, M. - 01a Articolo in rivista
rivista: BIOPOLYMERS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 85-92 - issn: 0006-3525 - wos: WOS:000248993000008 (6) - scopus: 2-s2.0-34548615093 (6)

11573/232776 - 2007 - Horseradish peroxidase in ionic liquids: Reactions with water insoluble phenolic substratesHorseradish peroxidase in ionic liquids
Sgalla, S; Fabrizi, Giancarlo; Cacchi, Sandro; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 144-148 - issn: 1381-1177 - wos: WOS:000244382300009 (61) - scopus: 2-s2.0-33846528913 (76)

11573/234791 - 2007 - Chiral (R)- and (S)-allylic alcohols via a one-pot chemoenzymatic synthesis
Simona, Sgalla; Fabrizi, Giancarlo; Roberto, Cirilli; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto; Cacchi, Sandro - 01a Articolo in rivista
rivista: TETRAHEDRON-ASYMMETRY (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB) pp. 2791-2796 - issn: 0957-4166 - wos: WOS:000252186200009 (24) - scopus: 2-s2.0-36649027299 (27)

11573/236913 - 2006 - The desaturase from Bacillus subtilis, a promising tool for the selective olefination of phospholipids
Bonamore, Alessandra; Macone, Alberto; Gianni, Colotti; Matarese, Rosa Marina; Boffi, Alberto - 01a Articolo in rivista
rivista: JOURNAL OF BIOTECHNOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 49-53 - issn: 0168-1656 - wos: WOS:000234292000005 (7) - scopus: 2-s2.0-28444443442 (7)

11573/237953 - 2006 - Interaction of Vitreoscilla Hemoglobin with Membrane Lipids.
Rinaldi A., C; Bonamore, Alessandra; Macone, Alberto; Boffi, Alberto; Bozzi, A; Di Giulio, A. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 4069-4076 - issn: 0006-2960 - wos: WOS:000236521300003 (31) - scopus: 2-s2.0-33645541767 (33)

11573/238376 - 2005 - A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca.
Bonamore, Alessandra; Ilari, Andrea; Giangiacomo, L; Bellelli, Andrea; Morea, V; Boffi, Alberto - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4189-4201 - issn: 1742-464X - wos: WOS:000231021400016 (47) - scopus: 2-s2.0-23844469133 (48)

11573/232262 - 2004 - Unusual heme iron-lipid acyl chain coordination in Escherichia coli flavohemoglobin
D'angelo, Paola; Lucarelli, Debora; Della Longa, Stefano; Benfatto, Maurizio; Hazemann, Jean Louis; Feis, Alessandro; Smulevich, Giulietta; Ilari, Andrea; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 3882-3892 - issn: 0006-3495 - wos: WOS:000222035200048 (41) - scopus: 2-s2.0-2942696586 (42)

11573/254162 - 2003 - Interaction with Membrane Lipids and Heme Ligand Binding Properties of Escherichia coli Flavohemoglobin.
Bonamore, Alessandra; Farina, A; Gattoni, Maurizio; Schinina', Maria Eugenia; Bellelli, Andrea; Boffi, Alberto - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 5792-5801 - issn: 0006-2960 - wos: WOS:000182934300028 (40) - scopus: 2-s2.0-0038629108 (43)

11573/250640 - 2003 - Escherichia coli flavohemoglobin is an efficient alkylhydroperoxide reductase
Bonamore, Alessandra; Gentili, Patrizia; Ilari, Andrea; Schininà, M. Eugenia; Boffi, Alberto - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 22272-22277 - issn: 0021-9258 - wos: WOS:000183503900014 (43) - scopus: 2-s2.0-0037929111 (43)

11573/140737 - 2002 - The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unexpected geometry of the distal heme pocket
Ilari, Andrea; Bonamore, Alessandra; Farina, A; Johnson K., A; Boffi, Alberto - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 23725-23732 - issn: 0021-9258 - wos: WOS:000176475700082 (120) - scopus: 2-s2.0-0037189541 (125)

11573/140736 - 2001 - The distal heme pocket of Escherichia coli flavohemoglobin probed by infrared spectroscopy
Bonamore, Alessandra; Chiancone, Emilia; Boffi, Alberto - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 174-178 - issn: 0005-2728 - wos: WOS:000172091400006 (22) - scopus: (0)

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