ALESSANDRA BONAMORE

Associate professor


email: alessandra.bonamore@uniroma1.it
phone: 0692727649
building: CU027
room: 208

WORK EXPERIENCE
[ 2017 – Current ] Associate Professor, Biochemistry BIO/10
Sapienza, University of Rome
City: Rome
Country: Italy
Teaching and research activity
[ 2008 – 2017 ] Researcher, Molecular Biology BIO/11
Sapienza, University of Rome
City: Roma
Country: Italy
Research and teaching activity
Post-doctoral fellow
Sapienza, University of Rome
City: Rome
Country: Italy
Research activity
EDUCATION AND TRAINING
[ 2001 – 2004 ] PhD in Biochemistry
Sapienza, University of Rome https://www.uniroma1.it/it/
City: Rome
Country: Italy
[ 1994 – 2020 ] Degree in Biology
Sapienza, University of Rome https://www.uniroma1.it/it/
City: Rome
Country: Italy
SCIENTIFIC ACTIVITY
Protein engineering for biocatalysis. This research focuses on bacterial hemoglobins and enzymes specifically engineered for biocatalytic applications, with a keen emphasis on their industrial and biotechnological relevance. The investigation extends to the eco-sustainable production of pharmaceutical intermediates and biologically active substances utilizing recombinant enzymes, including allyl alcohol dehydrogenase, pictet-spenglerase, prenyltransferase, and cytochromes P450, or purified enzymes derived from plants, such as amino oxidases.
Protein engineering for drug delivery. This research centers on the development of innovative ferritin-based nanocarriers tailored for the targeted delivery of imaging agents and therapeutics to tumor cells. Particular attention is devoted to facilitating the targeted delivery of unconventional drugs, including therapeutic proteins, peptides, and small RNA molecules. The research activity was conducted in the frame of several projects, including two European projects (X-Probe (637295) and ProMeTeus (823780)), three PRIN projects (2004, 2008, and 2022), one FIRB project (2008).

TEACHING ACTIVITY
Current teaching activity
Teaching course, faculty, place.
Molecular Biology, Biochemistry Course, Degree in Medicine and Surgery E - Faculty of Pharmacy
and Medicine - Sapienza University of Rome - Polo Pontino.
Molecular Biology, Integrated Course in Biochemical Foundations of Diagnostic Sciences, Degree in Biomedical Laboratory Techniques – Faculty of Pharmacy and Medicine - Sapienza University of Rome - Polo Pontino.
Biochemistry, Integrated Course in Biochemical Foundations of Diagnostic Sciences, Degree in
Biomedical Laboratory Techniques – Faculty of Pharmacy and Medicine - Sapienza University of Rome - Polo Pontino.
Management and Innovation in Biotechnology, Degree in Biomedical Scientific Communication – Interfaculty Course (Pharmacy and Medicine, Political Science, Sociology, Communication) - Sapienza University of Rome – Rome.


Research products

11573/1700809 - 2024 - Design of protein-binding peptides with controlled binding affinity: the case of SARS-CoV-2 receptor binding domain and angiotensin-converting enzyme 2 derived peptides
Parisi, G.; Piacentini, R.; Incocciati, A.; Bonamore, A.; Macone, A.; Rupert, J.; Zacco, E.; Miotto, M.; Milanetti, E.; Tartaglia, G. G.; Ruocco, G.; Boffi, A.; Di Rienzo, L. - 01a Articolo in rivista
paper: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-889X - wos: WOS:001144542200001 (1) - scopus: 2-s2.0-85182672420 (1)

11573/1676431 - 2023 - Ferritin-coated SPIONs as new cancer cell targeted magnetic nanocarrier
Affatigato, L.; Licciardi, M.; Bonamore, A.; Martorana, A.; Incocciati, A.; Boffi, A.; Militello, V. - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1163- - issn: 1420-3049 - wos: WOS:000929543400001 (3) - scopus: 2-s2.0-85147895486 (4)

11573/1676430 - 2023 - Engineered Ferritin with Eu3+ as a Bright Nanovector: A Photoluminescence Study
Affatigato, L.; Sciortino, A.; Sancataldo, G.; Incocciati, A.; Piacentini, R.; Bonamore, A.; Cannas, M.; Messina, F.; Licciardi, M.; Militello, V. - 01a Articolo in rivista
paper: PHOTOCHEMISTRY AND PHOTOBIOLOGY (American Society of Photobiology:1021 15th Street, Suite 9:Augusta, GA 30901:(706)722-7511, EMAIL: executive.office@asanet.org, INTERNET: http://www.asanet.org, Fax: (706)722-7515 Editore precedente:Pergamon Press.) pp. - - issn: 0031-8655 - wos: WOS:000907573000001 (0) - scopus: 2-s2.0-85145504623 (0)

11573/1688526 - 2023 - Harnessing buffer solutions to modify the association state of Ferritin nanoparticles
Incocciati, A.; Cappelletti, C.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
paper: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 414- - issn: 2297-8739 - wos: WOS:001039630400001 (0) - scopus: 2-s2.0-85166399696 (0)

11573/1692513 - 2023 - Hydrophobicity‐enhanced ferritin nanoparticles for efficient encapsulation and targeted delivery of hydrophobic drugs to tumor cells
Incocciati, Alessio; Kubeš, Jan; Piacentini, Roberta; Cappelletti, Chiara; Botta, Sofia; Bertuccini, Lucia; Šimůnek, Tomáš; Boffi, Alberto; Macone, Alberto; Bonamore, Alessandra - 01a Articolo in rivista
paper: PROTEIN SCIENCE (Bognor Regis: Wiley Cambridge: Cambridge University Press) pp. - - issn: 1469-896X - wos: WOS:001107660800001 (1) - scopus: 2-s2.0-85177462333 (3)

11573/1648657 - 2022 - Immobilization of Lathyrus cicera amine oxidase on magnetic microparticles for biocatalytic applications
Di Fabio, Elisa; Iazzetti, Antonia; Incocciati, Alessio; Caseli, Valentina; Fabrizi, Giancarlo; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 6529- - issn: 1422-0067 - wos: WOS:000818208500001 (2) - scopus: 2-s2.0-85131542371 (3)

11573/1615111 - 2022 - Rapid and simultaneous determination of free aromatic carboxylic acids and phenols in commercial juices by GC-MS after ethyl chloroformate derivatization
Incocciati, A.; Di Fabio, E.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
paper: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 9- - issn: 2297-8739 - wos: WOS:000758392000001 (1) - scopus: 2-s2.0-85123755357 (3)

11573/1660680 - 2022 - Unlocking the treasure box: the role of HEPES buffer in disassembling an uncommon ferritin nanoparticle
Incocciati, A; Bertuccini, L; Boffi, A; Macone, A; Bonamore, A - 01a Articolo in rivista
paper: SEPARATIONS (Basel : MDPI AG, 2016-) pp. 222- - issn: 2297-8739 - wos: WOS:000845227300001 (3) - scopus: 2-s2.0-85136693526 (3)

11573/1621727 - 2021 - Biocatalytic production of aldehydes: exploring the potential of lathyrus cicera amine oxidase
Di Fabio, E.; Incocciati, A.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
paper: BIOMOLECULES (Basel: MDPI) pp. 1540- - issn: 2218-273X - wos: WOS:000828673600001 (2) - scopus: 2-s2.0-85117071209 (4)

11573/1551118 - 2021 - Exciplex formation in lipid-bound Escherichia coli flavohemoglobin
Marcelli, A.; Patrizi, B.; Bonamore, A.; Boffi, A.; Becucci, M.; Foggi, P. - 01a Articolo in rivista
paper: CHEMPHYSCHEM (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1134-1140 - issn: 1439-4235 - wos: WOS:000644988900001 (0) - scopus: 2-s2.0-85105032084 (0)

11573/1554362 - 2021 - Self-assembling ferritin-dendrimer nanoparticles for targeted delivery of nucleic acids to myeloid leukemia cells
Palombarini, F.; Masciarelli, S.; Incocciati, A.; Liccardo, F.; Di Fabio, E.; Iazzetti, A.; Fabrizi, G.; Fazi, F.; Macone, A.; Bonamore, A.; Boffi, A. - 01a Articolo in rivista
paper: JOURNAL OF NANOBIOTECHNOLOGY (London : BioMed Central.) pp. 1-12 - issn: 1477-3155 - wos: WOS:000660095400001 (30) - scopus: 2-s2.0-85107462102 (33)

11573/1447230 - 2020 - Ethylchloroformate derivatization for GC-MS analysis of resveratrol isomers in red wine
Di Fabio, E.; Incocciati, A.; Palombarini, F.; Boffi, A.; Bonamore, A.; Macone, A. - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 4603- - issn: 1420-3049 - wos: WOS:000583012000001 (6) - scopus: 2-s2.0-85092519779 (6)

11573/1448485 - 2020 - Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice
Kiraga, L.; Cerutti, G.; Braniewska, A.; Strzemecki, D.; Sas, Z.; Boffi, A.; Savino, C.; Montemiglio, L. C.; Turnham, D.; Seaton, G.; Bonamore, A.; Clarkson, R.; Dabkowski, A. M.; Paisey, S. J.; Taciak, B.; Kucharzewska, P.; Rygiel, T. P.; Krol, M. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 1-15 - issn: 1661-6596 - wos: WOS:000554130900001 (1) - scopus: 2-s2.0-85087932608 (1)

11573/1448470 - 2020 - Ferritin nanocages for protein delivery to tumor cells
Palombarini, F.; Di Fabio, E.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 825- - issn: 1420-3049 - wos: WOS:000522454500061 (42) - scopus: 2-s2.0-85079643167 (46)

11573/1316071 - 2019 - A gas chromatographic–mass spectrometric method for the simultaneous determination of resveratrol isomers and 2,4,6-trihydroxyphenanthrene in red wines exposed to UV-light
Francioso, Antonio; Laštovičková, Lenka; Mosca, Luciana; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto - 01a Articolo in rivista
paper: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 11752-11757 - issn: 0021-8561 - wos: WOS:000492802400022 (10) - scopus: 2-s2.0-85073189936 (10)

11573/1313577 - 2019 - Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells
Macone, A.; Masciarelli, S.; Palombarini, Federica; Quaglio, D.; Boffi, A.; Trabuco, M. C.; Baiocco, P.; Fazi, F.; Bonamore, A. - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11749- - issn: 2045-2322 - wos: WOS:000480517100029 (43) - scopus: 2-s2.0-85070764634 (45)

11573/1316082 - 2019 - Application of crossflow ultrafiltration for scaling up the purification of a recombinant ferritin
Palombarini, F.; Ghirga, F.; Boffi, A.; Macone, A.; Bonamore, A. - 01a Articolo in rivista
paper: PROTEIN EXPRESSION AND PURIFICATION (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495) pp. - - issn: 1046-5928 - wos: WOS:000481561700007 (13) - scopus: 2-s2.0-85068569345 (15)

11573/1121880 - 2018 - Excimer based fluorescent pyrene-ferritin conjugate for protein oligomerization studies and imaging in living cells
Benni, Irene; Trabuco, Matilde Cardoso; Di Stasio, Enrico; Arcovito, Alessandro; Boffi, Alberto; Malatesta, Francesco; Bonamore, Alessandra; De Panfilis, Simone; De Turris, Valeria; Baiocco, Paola - 01a Articolo in rivista
paper: RSC ADVANCES (London: Royal Society of Chemistry) pp. 12815-12822 - issn: 2046-2069 - wos: WOS:000429450000038 (10) - scopus: 2-s2.0-85045180344 (11)

11573/1175774 - 2018 - Engineered ferritin for lanthanide binding
Calisti, Lorenzo; Cardoso Trabuco, Matilde; Boffi, Alberto; Testi, Claudia; Montemiglio, Linda Celeste; Des Georges, Amédée; Benni, Irene; Ilari, Andrea; Taciak, Bartłomiej; Białasek, Maciej; Rygiel, Tomasz; Krol, Magdalena; Baiocco, Paola; Bonamore, Alessandra - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000441452200019 (23) - scopus: 2-s2.0-85051486677 (23)

11573/928790 - 2017 - Humanized archaeal ferritin as a tool for cell targeted delivery
De Turris, Valeria; Cardoso Trabuco, Matilde; Peruzzi, Giovanna; Boffi, Alberto; Testi, Claudia; Vallone, Beatrice; Celeste Montemiglio, Linda; Georges, Amédée Des; Calisti, Lorenzo; Benni, Irene; Bonamore, Alessandra; Baiocco, Paola - 01a Articolo in rivista
paper: NANOSCALE (Cambridge,UK: RCS PUBLISHING -Royal Society of Chemistry) pp. 647-655 - issn: 2040-3364 - wos: WOS:000394780200022 (28) - scopus: 2-s2.0-85008894536 (30)

11573/1021474 - 2017 - Green routes for the production of enantiopure benzylisoquinoline alkaloids
Ghirga, Francesca; Bonamore, Alessandra; Calisti, Lorenzo; D'acquarica, Ilaria; Mori, Mattia; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000416811300234 (9) - scopus: 2-s2.0-85034960303 (10)

11573/867977 - 2016 - Mapping the amide I absorption in single bacteria and mammalian cells with resonant infrared nanospectroscopy
Baldassarre, Leonetta; Giliberti, Valeria; Rosa, Alessandro; Ortolani, Michele; Bonamore, Alessandra; Baiocco, Paola; Kjoller, K.; Calvani, Paolo; Nucara, Alessandro - 01a Articolo in rivista
paper: NANOTECHNOLOGY (Bristol, United Kingdom: IOP Publishing Limited) pp. 075101- - issn: 0957-4484 - wos: WOS:000368935000006 (51) - scopus: 2-s2.0-84955465361 (47)

11573/884656 - 2016 - A novel enzymatic strategy for the synthesis of substituted tetrahydroisoquinolines
Bonamore, Alessandra; Calisti, Lorenzo; Calcaterra, Andrea; Ismail, Omar Habib; Gargano, Maurizio; D'acquarica, Ilaria; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
paper: CHEMISTRYSELECT (John Wiley & Sons, Inc) pp. 1525-1528 - issn: 2365-6549 - wos: WOS:000395407100002 (18) - scopus: 2-s2.0-85029937881 (20)

11573/928785 - 2016 - Probing bulky ligand entry in engineered archaeal ferritins
Calisti, Lorenzo; Benni, Irene; Cardoso Trabuco, Matilde; Baiocco, Paola; Ruzicka, Barbara; Boffi, Alberto; Falvo, Elisabetta; Malatesta, Francesco; Bonamore, Alessandra - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 450-456 - issn: 0304-4165 - wos: WOS:000392680200042 (11) - scopus: 2-s2.0-85001820140 (11)

11573/821477 - 2015 - A Novel Direct Method for Determination of Riboflavin in Alcoholic Fermented Beverages
Bonamore, Alessandra; Gargano, Maurizio; Calisti, Lorenzo; Francioso, Antonio; Mosca, Luciana; Boffi, Alberto; Federico, Rodolfo - 01a Articolo in rivista
paper: FOOD ANALYTICAL METHODS (New York, NY : Springer Science and Business Media) pp. - - issn: 1936-9751 - wos: WOS:000371257000004 (6) - scopus: 2-s2.0-84959075759 (6)

11573/839384 - 2015 - Electrocatalytic interconversion of NADH and NAD+ by Escherichia coli flavohemoglobin
Shipovskov, S.; Bonamore, Alessandra; Boffi, Alberto; Ferapontova, E. E. - 01a Articolo in rivista
paper: CHEMICAL COMMUNICATIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 16096-16098 - issn: 1359-7345 - wos: WOS:000363666000018 (11) - scopus: 2-s2.0-84946041332 (13)

11573/675815 - 2014 - New Engineered Archaeoglobus fulgidus Ferritin as Supramolecular Biotransducer for SPR-based Biosensors
Boffi, Alberto; Bonamore, Alessandra; Sanzo', Gabriella; Tortolini, Cristina; Favero, Gabriele; Mazzei, Franco - 04a Atto di comunicazione a congresso
conference: BioSensors 2014 (Melbourne)
book: Proceedings of the 24th World Anniversary Congress on Biosensors - ()

11573/556311 - 2014 - Molecular basis of thermal stability in truncated (2/2) hemoglobins
Juan P., Bustamante; Bonamore, Alessandra; Alejandro D., Nadra; Natascia, Sciamanna; Boffi, Alberto; Darío A., Estrin; Leonardo, Boechi - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0304-4165 - wos: WOS:000338402400019 (9) - scopus: 2-s2.0-84899789832 (9)

11573/548142 - 2014 - Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins
Juan P., Bustamante; Stefania, Abbruzzetti; Agnese, Marcelli; Diego, Gauto; Leonardo, Boechi; Bonamore, Alessandra; Boffi, Alberto; Stefano, Bruno; Alessandro, Feis; Paolo, Foggi; Dario A., Estrin; Cristiano, Viappiani - 01a Articolo in rivista
paper: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. 1234-1245 - issn: 1520-6106 - wos: WOS:000331153800007 (19) - scopus: 2-s2.0-84893831206 (24)

11573/782766 - 2014 - Interplay of the H-bond donor-acceptor role of the distal residues in hydroxyl ligand stabilization of Thermobifida fusca truncated hemoglobin
Nicoletti, F. P.; Bustamante, J. P.; Droghetti, E.; Howes, B. D.; Fittipaldi, M.; Bonamore, Alessandra; Baiocco, P.; Feis, A.; Boffi, Alberto; Estrin, D.; Smulevich, G. - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 8021-8030 - issn: 0006-2960 - wos: WOS:000347437700004 (14) - scopus: 2-s2.0-84920094601 (14)

11573/782772 - 2014 - Role of local structure and dynamics of small ligand migration in proteins: A study of a mutated truncated hemoprotein from Thermobifida fusca by time resolved MIR spectroscopy
Patrizi, B.; Lapini, A.; Di Donato, M.; Marcelli, A.; Lima, M.; Righini, R.; Foggi, P.; Baiocco, P.; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
paper: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. 9209-9217 - issn: 1520-6106 - wos: WOS:000340223000009 (5) - scopus: 2-s2.0-84905731127 (5)

11573/508130 - 2013 - Direct electrochemistry and Os-polymer-mediated bioelectrocatalysis of NADH oxidation by Escherichia coli flavohemoglobin at graphite electrodes
Maciej, Sosna; Bonamore, Alessandra; Gorton, Lo; Boffi, Alberto; Elena E., Ferapontova - 01a Articolo in rivista
paper: BIOSENSORS & BIOELECTRONICS (Barking: Elsevier Science Publishers) pp. 219-224 - issn: 0956-5663 - wos: WOS:000309404100011 (19) - scopus: 2-s2.0-84871666727 (30)

11573/515797 - 2013 - H-bonding networks of the distal residues and water molecules in the active site of Thermobifida fusca hemoglobin
Nicoletti, Fp; Droghetti, E; Howes, Bd; Bustamante, Jp; Bonamore, Alessandra; Sciamanna, Natascia; Estrin, Da; Feis, A; Boffi, Alberto; Smulevich, G. - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0006-3002 - wos: WOS:000323191800025 (20) - scopus: 2-s2.0-84884641056 (21)

11573/468132 - 2012 - Enzymatic, stereoselective synthesis of (S)-norcoclaurine.
Bonamore, Alessandra; Macone, Alberto - 02a Capitolo o Articolo
book: Practical Methods for Biocatalysis and Biotransformations 2 - (9781119991397)

11573/508757 - 2012 - C–C Bond Formation and Decarboxylation
Bonamore, Alessandra; Macone, Alberto; Kroutil, Wolfgang; Seisser, Birgit; Lammens, Tijs M.; De Biase, Daniela; Franssen, Maurice C. R.; Scott, Elinor L.; Sanders, Johan P. M.; Miyamoto, Kenji; Kourist, Robert; Yoshida, Shosuke; Ohta, Hiromichi; Tian, Jie; Li, Heng; Gao, Wen-Yun; Shanmuganathan, Saravanakumar; Natalia, D.; Greiner, Lasse; Domínguez De Maria, Pablo; He, Yan-Hong; Guan, Zhi; Cai, Jian-Feng - 02a Capitolo o Articolo
book: Practical Methods for Biocatalysis and Biotransformations 2 - (9781119943426; 9781119991397)

11573/484812 - 2012 - Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca.
Marcelli, A; Abbruzzetti, S; Bustamante, Jp; Feis, A; Bonamore, Alessandra; Boffi, Alberto; Gellini, C; Salvi, Pr; Estrin, Da; Bruno, S; Viappiani, C; Foggi, P. - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. 1-12 - issn: 1932-6203 - wos: WOS:000306461800024 (20) - scopus: 2-s2.0-84863638846 (21)

11573/406737 - 2012 - Production of bioactive compounds: the importance of Pictet-Spengler reaction in the XXI century
P., Menendez; D'acquarica, Ilaria; G., Delle Monache; Ghirga, Francesca; Calcaterra, Andrea; Barba, Marco; Macone, Alberto; Boffi, Alberto; Bonamore, Alessandra; Botta, Bruno - 02a Capitolo o Articolo
book: Bioactive Principles from Plants and Drug Discovery: Practice and Perspectives - (9780470582268)

11573/390983 - 2011 - The optical spectra of fluoride complexes can effectively probe H-bonding interactions in the distal cavity of heme proteins
Enrica, Droghetti; Francesco P., Nicoletti; Bonamore, Alessandra; Sciamanna, Natascia; Boffi, Alberto; Alessandro, Feis; Giulietta, Smulevich - 01a Articolo in rivista
paper: JOURNAL OF INORGANIC BIOCHEMISTRY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. 1338-1343 - issn: 0162-0134 - wos: WOS:000295423700010 (23) - scopus: 2-s2.0-84860389795 (23)

11573/442627 - 2011 - Fluoride as a Probe for H-Bonding Interactions in the Active Site of Heme Proteins: The Case of Thermobifida fusca Hemoglobin
Francesco P., Nicoletti; Enrica, Droghetti; Leonardo, Boechi; Bonamore, Alessandra; Sciamanna, Natascia; Dario A., Estrin; Alessandro, Feis; Boffi, Alberto; Giulietta, Smulevich - 01a Articolo in rivista
paper: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 20970-20980 - issn: 0002-7863 - wos: WOS:000298571600049 (29) - scopus: 2-s2.0-84555177994 (29)

11573/226895 - 2010 - Unusual proximal heme pocket geometry in the deoxygenated Thermobifida fusca: A combined spectroscopic investigation
Alessandro, Arcovito; Bonamore, Alessandra; Jean Louis, Hazemann; Boffi, Alberto; D'angelo, Paola - 01a Articolo in rivista
paper: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1-7 - issn: 0301-4622 - wos: WOS:000274709900001 (4) - scopus: 2-s2.0-75549089304 (4)

11573/226629 - 2010 - Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme
Bonamore, Alessandra; Barba, Marco; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 2070-2078 - issn: 1420-3049 - wos: WOS:000277147400002 (34) - scopus: 2-s2.0-77951848665 (38)

11573/376102 - 2010 - An enzymatic, stereoselective synthesis of (S)-norcoclaurine
Bonamore, Alessandra; Rovardi, Irene; Gasparrini, Francesco; Baiocco, Paola; Barba, Marco; Molinaro, Carmela; Botta, Bruno; Boffi, Alberto; Macone, Alberto - 01a Articolo in rivista
paper: GREEN CHEMISTRY (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 1623-1627 - issn: 1463-9262 - wos: WOS:000281613900018 (50) - scopus: 2-s2.0-77956389962 (56)

11573/377080 - 2010 - Heme Pocket Structural Properties of a Bacterial Truncated Hemoglobin from Thermobifida fusca
Enrica, Droghetti; Francesco Paolo, Nicoletti; Bonamore, Alessandra; Leonardo, Boechi; Pau Arroyo, Manez; Dario A., Estrin; Boffi, Alberto; Giulietta, Smulevich; Alessandro, Feis - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 10394-10402 - issn: 0006-2960 - wos: WOS:000284975000006 (23) - scopus: 2-s2.0-78650113583 (24)

11573/228330 - 2010 - Sulfide Binding Properties of Truncated Hemoglobins
Francesco P., Nicoletti; Alessandra, Comandini; Bonamore, Alessandra; Leonardo, Boechi; Fernando Martin, Boubeta; Alessandro, Feis; Giulietta, Smulevich; Boffi, Alberto - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 2269-2278 - issn: 0006-2960 - wos: WOS:000275227000019 (55) - scopus: 2-s2.0-77949408968 (61)

11573/224347 - 2009 - (R)-1-Arylethanols from aryl iodides through a two-step one-pot enantioselective chemoenzymatic process
Cacchi, Sandro; Roberto, Cirilli; Fabrizi, Giancarlo; Simona, Sgalla; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 184-187 - issn: 1381-1177 - wos: WOS:000272064600012 (9) - scopus: 2-s2.0-72049130562 (10)

11573/229201 - 2009 - Structural basis of enzymatic (S)-norcoclaurine biosynthesis
Ilari, Andrea; Franceschini, S; Bonamore, Alessandra; Arenghi, F; Botta, Bruno; Macone, Alberto; Pasquo, A; Bellucci, L; Boffi, Alberto - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 897-904 - issn: 0021-9258 - wos: WOS:000262122900024 (94) - scopus: 2-s2.0-59449099013 (101)

11573/226721 - 2009 - Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WT
Macone, Alberto; Lendaro, Eugenio; Alessandra, Comandini; Rovardi, Irene; Matarese, Rosa Marina; Antonio, Carraturo; Bonamore, Alessandra - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 6003-6007 - issn: 0968-0896 - wos: WOS:000268762900027 (11) - scopus: 2-s2.0-68149144266 (11)

11573/360869 - 2009 - Peroxidase-like activity of Thermobifida fusca hemoglobin: The oxidation of dibenzylbutanolide
Torge, Roberta; Alessandra, Comandini; Bruno, Catacchio; Bonamore, Alessandra; Botta, Bruno; Boffi, Alberto - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 303-308 - issn: 1381-1177 - wos: WOS:000272064600031 (13) - scopus: 2-s2.0-72049095862 (14)

11573/229453 - 2008 - Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum
Alessandra, Pasquo; Bonamore, Alessandra; Stefano, Franceschini; Macone, Alberto; Boffi, Alberto; Ilari, Andrea - 01a Articolo in rivista
paper: ACTA CRYSTALLOGRAPHICA. SECTION F, STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS (Malden, MA : Published for International Union of Crystallography by Blackwell) pp. 281-283 - issn: 1744-3091 - wos: WOS:000254473200014 (21) - scopus: 2-s2.0-41949092539 (23)

11573/141021 - 2008 - Globin interactions with lipids and membranes
Antonio Di, Giulio; Bonamore, Alessandra - 01a Articolo in rivista
paper: METHODS IN ENZYMOLOGY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 239-253 - issn: 0076-6879 - wos: WOS:000253294600013 (9) - scopus: 2-s2.0-42949117860 (9)
book: Globins and Other Nitric Oxide-Reactive Proteins, Part A - (9780123742773)

11573/226948 - 2008 - Flavohemoglobin: structure and reactivity.
Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
paper: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 19-28 - issn: 1521-6543 - wos: WOS:000252522000004 (79) - scopus: 2-s2.0-42949138420 (85)

11573/360024 - 2008 - The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity
Ilari, Andrea; Bonamore, Alessandra; Stefano, Franceschini; Fiorillo, Annarita; Boffi, Alberto; Gianni, Colotti - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 2065-2075 - issn: 0887-3585 - wos: WOS:000255920600037 (21) - scopus: 2-s2.0-44349132154 (25)

11573/362080 - 2007 - A novel chimera: the "truncated hemoglobin-antibiotic monooxygenase" from Streptomyces avermitilis.
Bonamore, Alessandra; Attili, A; Arenghi, F; B., Catacchio; Chiancone, Emilia; Morea, V; Boffi, Alberto - 01a Articolo in rivista
paper: GENE (Amsterdam Netherlands: Elsevier BV) pp. 52-61 - issn: 0378-1119 - wos: WOS:000248784200007 (13) - scopus: 2-s2.0-34447537731 (14)

11573/239779 - 2007 - Folding propensity and biological activity of peptides: New insights from conformational properties of a novel peptide derived from Vitreoscilla haemoglobin.
Bozzi, A; Coccia, C; Di Giulio, A; Rinaldi A., C; Amadei, A; Mignogna, Giuseppina; Bonamore, Alessandra; Feis, A; Aschi, M. - 01a Articolo in rivista
paper: BIOPOLYMERS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 85-92 - issn: 0006-3525 - wos: WOS:000248993000008 (6) - scopus: 2-s2.0-34548615093 (6)

11573/232776 - 2007 - Horseradish peroxidase in ionic liquids: Reactions with water insoluble phenolic substratesHorseradish peroxidase in ionic liquids
Sgalla, S; Fabrizi, Giancarlo; Cacchi, Sandro; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
paper: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 144-148 - issn: 1381-1177 - wos: WOS:000244382300009 (61) - scopus: 2-s2.0-33846528913 (75)

11573/234791 - 2007 - Chiral (R)- and (S)-allylic alcohols via a one-pot chemoenzymatic synthesis
Simona, Sgalla; Fabrizi, Giancarlo; Roberto, Cirilli; Macone, Alberto; Bonamore, Alessandra; Boffi, Alberto; Cacchi, Sandro - 01a Articolo in rivista
paper: TETRAHEDRON-ASYMMETRY (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB) pp. 2791-2796 - issn: 0957-4166 - wos: WOS:000252186200009 (23) - scopus: 2-s2.0-36649027299 (26)

11573/236913 - 2006 - The desaturase from Bacillus subtilis, a promising tool for the selective olefination of phospholipids
Bonamore, Alessandra; Macone, Alberto; Gianni, Colotti; Matarese, Rosa Marina; Boffi, Alberto - 01a Articolo in rivista
paper: JOURNAL OF BIOTECHNOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 49-53 - issn: 0168-1656 - wos: WOS:000234292000005 (7) - scopus: 2-s2.0-28444443442 (7)

11573/237953 - 2006 - Interaction of Vitreoscilla Hemoglobin with Membrane Lipids.
Rinaldi A., C; Bonamore, Alessandra; Macone, Alberto; Boffi, Alberto; Bozzi, A; Di Giulio, A. - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 4069-4076 - issn: 0006-2960 - wos: WOS:000236521300003 (31) - scopus: 2-s2.0-33645541767 (33)

11573/238376 - 2005 - A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca.
Bonamore, Alessandra; Ilari, Andrea; Giangiacomo, L; Bellelli, Andrea; Morea, V; Boffi, Alberto - 01a Articolo in rivista
paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4189-4201 - issn: 1742-464X - wos: WOS:000231021400016 (47) - scopus: 2-s2.0-23844469133 (48)

11573/232262 - 2004 - Unusual heme iron-lipid acyl chain coordination in Escherichia coli flavohemoglobin
D'angelo, Paola; Lucarelli, Debora; Della Longa, Stefano; Benfatto, Maurizio; Hazemann, Jean Louis; Feis, Alessandro; Smulevich, Giulietta; Ilari, Andrea; Bonamore, Alessandra; Boffi, Alberto - 01a Articolo in rivista
paper: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 3882-3892 - issn: 0006-3495 - wos: WOS:000222035200048 (40) - scopus: 2-s2.0-2942696586 (41)

11573/254162 - 2003 - Interaction with Membrane Lipids and Heme Ligand Binding Properties of Escherichia coli Flavohemoglobin.
Bonamore, Alessandra; Farina, A; Gattoni, Maurizio; Schinina', Maria Eugenia; Bellelli, Andrea; Boffi, Alberto - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 5792-5801 - issn: 0006-2960 - wos: WOS:000182934300028 (39) - scopus: 2-s2.0-0038629108 (42)

11573/250640 - 2003 - Escherichia coli flavohemoglobin is an efficient alkylhydroperoxide reductase
Bonamore, Alessandra; Gentili, Patrizia; Ilari, Andrea; Schininà, M. Eugenia; Boffi, Alberto - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 22272-22277 - issn: 0021-9258 - wos: WOS:000183503900014 (42) - scopus: 2-s2.0-0037929111 (41)

11573/140737 - 2002 - The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unexpected geometry of the distal heme pocket
Ilari, Andrea; Bonamore, Alessandra; Farina, A; Johnson K., A; Boffi, Alberto - 01a Articolo in rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 23725-23732 - issn: 0021-9258 - wos: WOS:000176475700082 (117) - scopus: 2-s2.0-0037189541 (121)

11573/140736 - 2001 - The distal heme pocket of Escherichia coli flavohemoglobin probed by infrared spectroscopy
Bonamore, Alessandra; Chiancone, Emilia; Boffi, Alberto - 01a Articolo in rivista
paper: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 174-178 - issn: 0005-2728 - wos: WOS:000172091400006 (22) - scopus: (0)

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