Phd in LIFE SCIENCE

email: alessandra.bonamore@uniroma1.it
phone: 0692727649
building: CU027
room: 208

WORK EXPERIENCE
[ 2017 – Current ] Associate Professor, Biochemistry BIO/10
Sapienza, University of Rome
City: Rome
Country: Italy
Teaching and research activity
[ 2008 – 2017 ] Researcher, Molecular Biology BIO/11
Sapienza, University of Rome
City: Roma
Country: Italy
Research and teaching activity
Post-doctoral fellow
Sapienza, University of Rome
City: Rome
Country: Italy
Research activity
EDUCATION AND TRAINING
[ 2001 – 2004 ] PhD in Biochemistry
Sapienza, University of Rome https://www.uniroma1.it/it/
City: Rome
Country: Italy
[ 1994 – 2020 ] Degree in Biology
Sapienza, University of Rome https://www.uniroma1.it/it/
City: Rome
Country: Italy
SCIENTIFIC ACTIVITY
Protein engineering for biocatalysis. This research focuses on bacterial hemoglobins and enzymes specifically engineered for biocatalytic applications, with a keen emphasis on their industrial and biotechnological relevance. The investigation extends to the eco-sustainable production of pharmaceutical intermediates and biologically active substances utilizing recombinant enzymes, including allyl alcohol dehydrogenase, pictet-spenglerase, prenyltransferase, and cytochromes P450, or purified enzymes derived from plants, such as amino oxidases.
Protein engineering for drug delivery. This research centers on the development of innovative ferritin-based nanocarriers tailored for the targeted delivery of imaging agents and therapeutics to tumor cells. Particular attention is devoted to facilitating the targeted delivery of unconventional drugs, including therapeutic proteins, peptides, and small RNA molecules. The research activity was conducted in the frame of several projects, including two European projects (X-Probe (637295) and ProMeTeus (823780)), three PRIN projects (2004, 2008, and 2022), one FIRB project (2008).

TEACHING ACTIVITY
Current teaching activity
Teaching course, faculty, place.
Molecular Biology, Biochemistry Course, Degree in Medicine and Surgery E - Faculty of Pharmacy
and Medicine - Sapienza University of Rome - Polo Pontino.
Molecular Biology, Integrated Course in Biochemical Foundations of Diagnostic Sciences, Degree in Biomedical Laboratory Techniques – Faculty of Pharmacy and Medicine - Sapienza University of Rome - Polo Pontino.
Biochemistry, Integrated Course in Biochemical Foundations of Diagnostic Sciences, Degree in
Biomedical Laboratory Techniques – Faculty of Pharmacy and Medicine - Sapienza University of Rome - Polo Pontino.
Management and Innovation in Biotechnology, Degree in Biomedical Scientific Communication – Interfaculty Course (Pharmacy and Medicine, Political Science, Sociology, Communication) - Sapienza University of Rome – Rome.